{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:26:09Z","timestamp":1762867569716},"reference-count":8,"publisher":"World Scientific Pub Co Pte Lt","issue":"03","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hand Surg Asian-Pac Vol"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p> Background: Dupuytren\u2019s disease results in contracted cords in the hand that lead to deformity and disability. Current treatment options include fasciectomy and an injectable, collagenase clostridium histolyticum. No cost comparison studies have been published within the Australian health care environment. <\/jats:p><jats:p> Methods: A retrospective review of all patients treated for Dupuytren\u2019s disease in a major teaching hospital was undertaken to compare the costs of treatment by fasciectomy or collagenase injection. <\/jats:p><jats:p> Results: Eighteen patients underwent fasciectomy and 21 collagenase clostridium histolyticum injections were performed during the study period and were eligible for inclusion under the review criteria. Of the 39 patients, 36 were male and 3 were female with an average age 66.4 years (50\u201385). Twenty-five digits were treated by fasciectomy in 18 patients, and 23 digits were treated by collagenase in 21 patients. The fasciectomy group attended an average 9.2 visits (5\u201322), incurring an average costing of US$5738.12 per patient ($3181.18\u2013$9618.10). The collagenase group attended an average 3.8 visits (3\u20138), incurring an average costing of US$2076.83 per patient ($1842.24\u2013$3929.57). <\/jats:p><jats:p> Conclusions: Collagenase treatment of Dupuytren\u2019s contracture represents a significant reduction in cost relative to fasciectomy, with 64% savings, length of follow up and number of visits. This is a similar finding to studies in other countries. <\/jats:p>","DOI":"10.1142\/s2424835518500327","type":"journal-article","created":{"date-parts":[[2018,10,4]],"date-time":"2018-10-04T02:25:04Z","timestamp":1538619904000},"page":"336-341","source":"Crossref","is-referenced-by-count":16,"title":["Cost Comparison of Collagenase Clostridium Histolyticum and Fasciectomy for Treatment of Dupuytren\u2019s Contracture in the Australian Health System"],"prefix":"10.1142","volume":"23","author":[{"given":"Andrew K.","family":"Sefton","sequence":"first","affiliation":[{"name":"Department of Hand Surgery and Peripheral Nerve Surgery, Royal North Shore Hospital, Sydney Medical School, University of Sydney, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Belinda J.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Hand Surgery and Peripheral Nerve Surgery, Royal North Shore Hospital, Sydney Medical School, University of Sydney, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Stewart","sequence":"additional","affiliation":[{"name":"Department of Hand Surgery and Peripheral Nerve Surgery, Royal North Shore Hospital, Sydney Medical School, University of Sydney, Sydney, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2018,10,3]]},"reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12306-013-0304-x"},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-14-293"},{"key":"p_4","doi-asserted-by":"publisher","DOI":"10.1016\/j.main.2013.02.012"},{"key":"p_6","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-12-73"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-004166"},{"key":"p_8","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2013.12.030"},{"key":"p_10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0810866"},{"key":"p_11","doi-asserted-by":"publisher","DOI":"10.1007\/s12570-013-0237-8"}],"container-title":["The Journal of Hand Surgery (Asian-Pacific Volume)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S2424835518500327","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:29:25Z","timestamp":1565137765000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S2424835518500327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":8,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2018,10,3]]},"published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1142\/S2424835518500327"],"URL":"https:\/\/doi.org\/10.1142\/s2424835518500327","relation":{},"ISSN":["2424-8355","2424-8363"],"issn-type":[{"value":"2424-8355","type":"print"},{"value":"2424-8363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9]]}}}