{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T21:48:16Z","timestamp":1776462496575,"version":"3.51.2"},"reference-count":6,"publisher":"World Scientific Pub Co Pte Lt","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hand Surg Asian-Pac Vol"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:p>Background: In a small series, it has been postulated that delayed release of complex syndactyly of the 3rd web in Apert syndrome patients causes compression on epiphyses, with early epiphyseal closure, leading to symphalangism and reduced capitate ossification. We wished to see whether this remains true in a larger series.<\/jats:p><jats:p>Methods: We reviewed radiographs of 48 patients (86 hands) with Apert syndrome seen in the department of Plastic and Reconstructive Surgery, Great Ormond Street Hospital, between the years 2001\u20132012. Patients underwent surgical release of syndactyly in a staged fashion with the 3rd web release left until last. We measured the size of the capitate ossification center relative to that of the hamate and determined the relative position of the middle finger metacarpal relative to the ring finger metacarpal.<\/jats:p><jats:p>Results: We found agreement with many findings, however we weren\u2019t able to demonstrate the catch-up growth of the capitate after release of the third web. The failure of normal distal migration of the 3rd metacarpal appeared to occur until the 3rd web release is performed.<\/jats:p><jats:p>Conclusions: Consistent findings of delayed ossification of the capitate and failure of normal distal migration of the third metacarpal add support to the initial hypothesis, however, we cannot fully conclude that an earlier release of the third web is recommended, further research is still needed.<\/jats:p>","DOI":"10.1142\/s2424835520500113","type":"journal-article","created":{"date-parts":[[2020,1,31]],"date-time":"2020-01-31T09:16:56Z","timestamp":1580462216000},"page":"82-86","source":"Crossref","is-referenced-by-count":3,"title":["Radiographic Characteristics of the Hand in Apert Syndrome"],"prefix":"10.1142","volume":"25","author":[{"given":"Sharon Leigh","family":"Kracoff","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Kaplan Medical Center, Rehovot, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2020,1,31]]},"reference":[{"issue":"2","key":"p_1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0094-1298(20)30826-9","volume":"18","author":"Upton J","year":"1991","journal-title":"Clin Plast Surg."},{"key":"p_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199705010-00031"},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197052050-00003"},{"key":"p_4","doi-asserted-by":"publisher","DOI":"10.1097\/01.bth.0000185378.87246.61"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-195638050-00009"},{"key":"p_8","doi-asserted-by":"publisher","DOI":"10.1016\/j.hcl.2008.12.004"}],"container-title":["The Journal of Hand Surgery (Asian-Pacific Volume)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S2424835520500113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T02:46:04Z","timestamp":1614221164000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S2424835520500113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,31]]},"references-count":6,"journal-issue":{"issue":"01","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1142\/S2424835520500113"],"URL":"https:\/\/doi.org\/10.1142\/s2424835520500113","relation":{},"ISSN":["2424-8355","2424-8363"],"issn-type":[{"value":"2424-8355","type":"print"},{"value":"2424-8363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,31]]}}}