{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T23:26:44Z","timestamp":1779233204842,"version":"3.51.4"},"reference-count":11,"publisher":"World Scientific Pub Co Pte Ltd","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hand Surg Asian-Pac Vol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p> Background: The authors conducted a prospective, multi-centre study to assess the impact of carpal tunnel release (CTR) on Two-Point Discrimination (2-PD), Quick Disabilities of Arm, Shoulder and Hand Score (Q-DASH), and Distal Motor Latency (DL). The primary aim was to determine the change in outcome measurements (2-PD, Q-DASH and DL) preoperatively and postoperatively at 6 months and 1 year. The secondary aims of the study were to determine whether the postoperative outcomes were different at the 6-month and 1-year follow-up and if there was difference in outcomes based on the preoperative severity of carpal tunnel syndrome (CTS). <\/jats:p><jats:p> Methods: A total of 205 hands in 171 patients underwent CTR at five hospitals over a 2-year period. A total of 110 hands in 94 patients were followed-up and analysed. The 2-PD, Q-DASH and DL were measured for all patients preoperatively and at 6 months and 1 year postoperatively. Patients were divided into two groups \u2018mild\u2019 and \u2018severe\u2019 based on pre-operative DL score (mild \u2264 8.1 msec). The change in preoperative and postoperative 2-PD, Q-DASH and DL values were compared. The change in pre-operative and post-operative 2-PD and Q-DASH values were also compared between the \u2018mild\u2019 and \u2018severe\u2019 groups. <\/jats:p><jats:p> Results: The 2-PD, Q-DASH and DL showed significant improvement at 6-month and 1-year follow-ups compared to pre-operative values. However, there were no significant differences in all three parameters between the 6-month and 1-year measurements. There was significant improvement in preoperative and postoperative 2-PD and Q-DASH scores between the mild and severe groups. <\/jats:p><jats:p> Conclusions: CTR is an effective treatment for patients with CTS with significant improvement in all three outcome parameters (2-PD, Q-DASH and DL). The improvement in outcome plateaus at 6 months and additional follow-up may not be useful. <\/jats:p><jats:p> Level of Evidence: Level II (Therapeutic) <\/jats:p>","DOI":"10.1142\/s2424835522500941","type":"journal-article","created":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T03:22:49Z","timestamp":1671765769000},"page":"991-999","source":"Crossref","is-referenced-by-count":1,"title":["The Impact of Carpal Tunnel Release on Two-Point Discrimination, Quick Disabilities of Arm, Shoulder and Hand Score and Distal Motor Latency \u2013 A Multi-centre Prospective Study"],"prefix":"10.1142","volume":"27","author":[{"given":"Yukinobu","family":"KAMIYA","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Hokkaido Spinal Cord Injury Center, Bibai, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"MINAMI","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Hokkaido Spinal Cord Injury Center, Bibai, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuaki","family":"TOJO","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Hokkaido Spinal Cord Injury Center, Bibai, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoji","family":"MIKAMI","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yokohama Rosai Hospital, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norimasa","family":"IWASAKI","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Graduate School of Medicine, Hokkaido University, Sapporo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akinori","family":"SAKAI","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Occupational and Environmental Health, Kitakyusyu, 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