{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:14:26Z","timestamp":1788200066656,"version":"build-2803163510"},"reference-count":26,"publisher":"World Scientific Pub Co Pte Ltd","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hand Surg Asian-Pac Vol"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:p> Background: This study aimed to investigate the relationship between postoperative clinical results and long-term morphological changes in patients with carpal tunnel syndrome (CTS) as observed on magnetic resonance imaging (MRI) before and after open carpal tunnel release (OCTR). <\/jats:p><jats:p> Methods: We retrospectively analysed data for 28 hands that had undergone OCTR with at least 24 months of follow-up data. Two-point discrimination (2PD) test results were examined for the first three fingers, as were the distal motor latency (DML) and sensory conduction velocity (SCV) of the median nerve. We also calculated the cross-sectional area (CSA) of the carpal tunnel and the distance from the median nerve to the volar carpal bone at the hamate and the pisiform levels using MRI images. Variables were compared before and 24 months after OCTR. <\/jats:p><jats:p> Results: Significant improvements in all variables were observed, including average 2PD scores (Finger I: 13.1 \u00b1 6.2 vs. 7.7 \u00b1 4.3, p &lt; 0.01, Finger II: 11.9 \u00b1 6.6 vs. 7.0 \u00b1 3.5, p &lt; 0.01, Finger III: 13.6 \u00b1 6.1 vs. 7.8 \u00b1 4.5, p &lt; 0.01), average DML (8.3 \u00b1 3.3 vs. 4.3 \u00b1 0.6 m\/s, p &lt; 0.01), average SCV (30.8 \u00b1 11.0 vs. 41.3 \u00b1 5.3 m\/s, p &lt; 0.01), CSA of the carpal tunnel (hamate level: 194.9 \u00b1 30.6 vs. 254.2 \u00b1 47.6 mm<jats:sup>2<\/jats:sup>, p &lt; 0.01, pisiform level: 244.2 \u00b1 46.5 vs. 274.7 \u00b1 75.1 mm<jats:sup>2<\/jats:sup>, p = 0.01) and the distance between the median nerve and volar carpal bone (hamate level: 8.7 \u00b1 1.4 vs. 11.2 \u00b1 1.6 mm, p &lt; 0.01, pisiform level: 11.8 \u00b1 1.7 vs. 13.8 \u00b1 2.5 mm, p &lt; 0.01). <\/jats:p><jats:p> Conclusions: Our results demonstrate that OCTR is successful in achieving long-term decompression and recovery of the median nerve in patients with CTS. <\/jats:p><jats:p> Level of Evidence: Level III (Therapeutic) <\/jats:p>","DOI":"10.1142\/s2424835523500212","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T10:32:17Z","timestamp":1682505137000},"page":"197-204","source":"Crossref","is-referenced-by-count":5,"title":["Median Nerve Recovery and Morphological Change on MRI at 24 Months after Open Carpal Tunnel Release"],"prefix":"10.1142","volume":"28","author":[{"given":"Yusuke","family":"HATTORI","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"},{"name":"Department of Orthopaedic Surgery, Nagoya City University East Medical Center, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"KAWAGUCHI","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"USAMI","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan"},{"name":"Department of Orthopaedic Surgery, Nagoya City University East Medical Center, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"WAGURI-NAGAYA","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya City University East Medical Center, Nagoya, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"MURAKAMI","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, 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