{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:50:06Z","timestamp":1789707006180,"version":"4.0.1"},"reference-count":21,"publisher":"World Scientific Pub Co Pte Ltd","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Hand Surg Asian-Pac Vol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p> Background: De Quervain (DQ) tenosynovitis is a frequent source of wrist pain amongst middle-aged adults. Steroid injections are recommended after conservative methods fail, despite unclear mechanisms. The effectiveness of platelet-rich plasma (PRP) for DQ is not well-studied. To address this gap, we conducted a randomised controlled trial comparing the efficacy of PRP and corticosteroid (CS) injections for treating DQ. <\/jats:p><jats:p> Methods: This prospective, randomised and open-label trial was conducted at a tertiary care hospital in India. Adult patients aged 18\u201360 were randomly assigned to receive either ultrasound-guided triamcinolone acetonide injections or autologous PRP in the first extensor compartment. Outcomes were measured at baseline and at 1, 4 and 12 weeks using the VAS and quick disabilities of arm, shoulder and hand (QuickDASH) questionnaires. <\/jats:p><jats:p> Results: Eighty-six age- and sex-matched patients, with an average disease duration of 14 weeks in both groups, were enrolled. Both the CS and PRP groups demonstrated a significant reduction in pain scores and improvement in functions at 1, 4 and 12 weeks. However, between the groups, the degree of improvement in pain was more in CS group at 1 week and similar improvements between the groups at 4 and 12 weeks. Regarding hand function, the CS group exhibited notable at 1 and 4 weeks based on the QuickDASH scale. Yet, by the 12th week, hand function improvements were comparable between both groups. <\/jats:p><jats:p> Conclusions: This study suggests that PRP is equivalent to CS in reducing pain in DQ tenosynovitis. Hand function improved more significantly in the CS group at 1 and 4 weeks post-injection. Both PRP and CS are safe and equally effective treatments for DQ. <\/jats:p><jats:p> Level of Evidence: Level I (Therapeutic) <\/jats:p>","DOI":"10.1142\/s2424835525500249","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T08:57:54Z","timestamp":1736326674000},"page":"196-204","source":"Crossref","is-referenced-by-count":3,"title":["Platelet-Rich Plasma versus Corticosteroid Injection for the Treatment of de Quervain Tenosynovitis: A Randomised Control Open Label Equivalence Trial"],"prefix":"10.1142","volume":"30","author":[{"given":"Prasenjit","family":"CHOWLEY","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, R. G. Kar Medical College and Hospital, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harajit","family":"BISWAS","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, R. G. Kar Medical College and Hospital, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keshab","family":"MONDAL","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, R. G. Kar Medical College and Hospital, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shrabasti","family":"HAZRA","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, R. G. Kar Medical College and Hospital, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandipan","family":"HAZRA","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, R. G. Kar Medical College and Hospital, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pallab","family":"DAS","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, R. G. 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