{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:30:23Z","timestamp":1761766223752},"reference-count":36,"publisher":"World Scientific Pub Co Pte Lt","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Mech. Med. Biol."],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p> The biomechanical properties of the female pelvic floor tissues, such as muscles, fascia or ligaments are relevant when explaining pelvic disorders, since these may result from changes in the properties of those tissues. The aim of this study is to understand the influence of pelvic organ prolapse (POP) on the passive biomechanical properties of the pelvic floor muscles. For this purpose, magnetic resonance images at Valsalva maneuver were used, and an inverse finite element analysis technique was applied. The numerical models of the pubovisceralis muscle and pelvic bones were built from axial magnetic resonance images acquired at rest. The numerical simulation was based on the finite element method (FEM), by which the material constants were determined for three different constitutive models (Neo-Hookean, Mooney\u2013Rivlin and Yeoh). The ratio between the values of the material constants for women with and without prolapse was approximately 43% for the parameter [Formula: see text] in the Neo-Hookean constitutive model, 57% and 24% for [Formula: see text] and [Formula: see text] in the Mooney\u2013Rivlin constitutive model, and 35%, 21% and 14% for [Formula: see text], [Formula: see text] and [Formula: see text] in the Yeoh constitutive model. For the three constitutive models, the mean values of the material properties related with stiffness were higher for the muscles of women with POP. These increases in stiffness are in line with other experimental works involving vaginal tissue, which showing that the elasticity module is significantly higher in the prolapsed tissue when compared with normal tissue. <\/jats:p><jats:p> The present work presents a noninvasive methodology based on the application of the FEM, which allows the establishment of a relationship between the stiffness of the pelvic floor muscles of women with POP and without this pathology. <\/jats:p>","DOI":"10.1142\/s0219519417500907","type":"journal-article","created":{"date-parts":[[2017,7,5]],"date-time":"2017-07-05T03:43:19Z","timestamp":1499226199000},"page":"1750090","source":"Crossref","is-referenced-by-count":8,"title":["THE INFLUENCE OF PELVIC ORGAN PROLAPSE ON THE PASSIVE BIOMECHANICAL PROPERTIES OF PELVIC FLOOR MUSCLES"],"prefix":"10.1142","volume":"17","author":[{"given":"M. E. T.","family":"SILVA","sequence":"first","affiliation":[{"name":"LAETA, INEGI, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"given":"S.","family":"BRAND\u00c3O","sequence":"additional","affiliation":[{"name":"LAETA, INEGI, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"},{"name":"Department of Radiology, Centro Hospitalar de S\u00e3o Jo\u00e3o-EPE, Faculty of Medicine, University of Porto, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"}]},{"given":"M. P. L.","family":"PARENTE","sequence":"additional","affiliation":[{"name":"LAETA, INEGI, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]},{"given":"T.","family":"MASCARENHAS","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Centro Hospitalar de S\u00e3o Jo\u00e3o-EPE, Faculty of Medicine, University of Porto, Alameda Prof. Hern\u00e2ni Monteiro, 4200-319 Porto, Portugal"}]},{"given":"R. M.","family":"NATAL JORGE","sequence":"additional","affiliation":[{"name":"LAETA, INEGI, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal"}]}],"member":"219","published-online":{"date-parts":[[2017,9,28]]},"reference":[{"key":"S0219519417500907BIB001","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11080"},{"key":"S0219519417500907BIB002","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2006.01.055"},{"key":"S0219519417500907BIB003","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.124844"},{"key":"S0219519417500907BIB004","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1899"},{"key":"S0219519417500907BIB005","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2012.03219.x"},{"key":"S0219519417500907BIB006","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.123819"},{"key":"S0219519417500907BIB007","first-page":"1111","volume":"81","author":"Kuncharapu I","year":"2010","journal-title":"Am Fam Physician"},{"key":"S0219519417500907BIB008","doi-asserted-by":"publisher","DOI":"10.1148\/rg.284075139"},{"key":"S0219519417500907BIB009","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-010-1208-z"},{"key":"S0219519417500907BIB010","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-007-0533-3"},{"key":"S0219519417500907BIB011","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-006-0214-7"},{"key":"S0219519417500907BIB014","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(03)00008-3"},{"key":"S0219519417500907BIB015","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-007-0388-7"},{"key":"S0219519417500907BIB016","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2009.03.011"},{"key":"S0219519417500907BIB017","doi-asserted-by":"publisher","DOI":"10.1080\/10255842.2010.482045"},{"key":"S0219519417500907BIB018","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2008.06.037"},{"key":"S0219519417500907BIB019","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000250901.57095.ba"},{"key":"S0219519417500907BIB020","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4082"},{"key":"S0219519417500907BIB021","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2014.11.045"},{"key":"S0219519417500907BIB022","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-010-1178-1"},{"key":"S0219519417500907BIB023","doi-asserted-by":"publisher","DOI":"10.1177\/0954411916630571"},{"key":"S0219519417500907BIB024","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2011.11.010"},{"key":"S0219519417500907BIB025","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.02.033"},{"key":"S0219519417500907BIB026","doi-asserted-by":"publisher","DOI":"10.1016\/j.asoc.2013.05.012"},{"key":"S0219519417500907BIB027","doi-asserted-by":"publisher","DOI":"10.1007\/BF01593790"},{"key":"S0219519417500907BIB028","first-page":"360","volume":"3749","author":"Lee S","year":"2005","journal-title":"Medical Image Comput Comput Assist Intervention"},{"key":"S0219519417500907BIB029","first-page":"750","volume":"11","author":"Li X","year":"2008","journal-title":"Med Image Comput Comput - Assist Interv"},{"key":"S0219519417500907BIB030","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-012-2564-3"},{"key":"S0219519417500907BIB031","doi-asserted-by":"publisher","DOI":"10.1080\/10255840500405378"},{"key":"S0219519417500907BIB032","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-1305.2006.00257.x"},{"key":"S0219519417500907BIB033","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-008-0737-1"},{"key":"S0219519417500907BIB034","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-008-0695-7"},{"key":"S0219519417500907BIB035","doi-asserted-by":"publisher","DOI":"10.1159\/000343230"},{"key":"S0219519417500907BIB036","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.07.044"},{"key":"S0219519417500907BIB037","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.4829"},{"key":"S0219519417500907BIB038","doi-asserted-by":"publisher","DOI":"10.1016\/S0045-7825(97)00162-X"}],"container-title":["Journal of Mechanics in Medicine and Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S0219519417500907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T18:07:59Z","timestamp":1565114879000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S0219519417500907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":36,"journal-issue":{"issue":"06","published-online":{"date-parts":[[2017,9,28]]},"published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1142\/S0219519417500907"],"URL":"https:\/\/doi.org\/10.1142\/s0219519417500907","relation":{},"ISSN":["0219-5194","1793-6810"],"issn-type":[{"value":"0219-5194","type":"print"},{"value":"1793-6810","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9]]}}}