{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T18:11:06Z","timestamp":1770315066116,"version":"3.49.0"},"reference-count":41,"publisher":"World Scientific Pub Co Pte Ltd","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Mech. Med. Biol."],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>\n                    Pelvic organ prolapse (POP) is a condition that progressively affects women, leading to an increased demand for new treatment techniques. The current standard treatment is surgical correction, often highly invasive with associated risks and a relatively high failure rate. This study proposes an alternative approach using injectable biodegradable cog threads, commonly used in facial lifting. The 360\n                    <jats:sup>\u2218<\/jats:sup>\n                    4D barb threads, made of polycaprolactone (PCL), were tested to reinforce vaginal wall defects. Degradation and mechanical properties were evaluated after exposure to phosphate buffer solution (PBS) and potassium hydrogen phthalate (KHP) for 90 days and 180 days compared with a control group. Fourier transform infrared spectroscopy (FTIR) spectroscopy showed slight to moderate degradation over time in both media. Mechanical tensile tests revealed a reduction in maximum tensile strength by 13% to 19%, especially in PBS. However, cyclic tests indicated that the threads maintained significant mechanical strength, even after 100 load cycles, suggesting their potential for POP correction. The preliminary results from degradation and mechanical tests suggest that biodegradable PCL cog threads could serve as a promising new approach to prolapse correction, warranting further investigation.\n                  <\/jats:p>","DOI":"10.1142\/s0219519425500174","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T03:59:52Z","timestamp":1755143992000},"source":"Crossref","is-referenced-by-count":0,"title":["MECHANICAL CHARACTERIZATION AND DEGRADATION OF BIODEGRADABLE PCL COG THREADS FOR PELVIC ORGAN PROLAPSE TREATMENT"],"prefix":"10.1142","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0569-995X","authenticated-orcid":false,"given":"F\u00c1BIO","family":"PINHEIRO","sequence":"first","affiliation":[{"name":"LAETA, INEGI, Instituto Ci\u00eancias Biom\u00e9dicas Abel Salazar, Universidade do Porto, Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7146-9944","authenticated-orcid":false,"given":"ANT\u00d3NIO AUGUSTO","family":"FERNANDES","sequence":"additional","affiliation":[{"name":"LAETA, INEGI, Faculdade de Engenharia, Universidade do Porto, Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1059-715X","authenticated-orcid":false,"given":"AB\u00cdLIO","family":"JESUS","sequence":"additional","affiliation":[{"name":"LAETA, INEGI, Faculdade de Engenharia, Universidade do Porto, Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0018-9363","authenticated-orcid":false,"given":"ANA COLETTE","family":"MAUR\u00cdCIO","sequence":"additional","affiliation":[{"name":"Departamento de Cl\u00ednicas Veterin\u00e1rias, Instituto de Ci\u00eancias Biom\u00e9dicas de Abel Salazar (ICBAS), Universidade do Porto (UP), Rua de Jorge Viterbo Ferreira, no 228, 4050-313 Porto, Portugal"},{"name":"Centro de Estudos de Ci\u00eancia Animal (CECA), Instituto de Ci\u00eancias, Tecnologias e Agroambiente da Universidade do Porto (ICETA), Rua D. Manuel II, Apartado 55142, 4051-401 Porto, Portugal"},{"name":"Associate Laboratory for Animal and Veterinary Science (AL4AnimalS), 1300-477 Lisboa, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5016-0868","authenticated-orcid":false,"given":"NUNO","family":"ALVES","sequence":"additional","affiliation":[{"name":"CDRSP Instituto Polit\u00e9cnico de Leiria, Marinha Grande, Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2889-4969","authenticated-orcid":false,"given":"MARIA ELISABETE","family":"SILVA","sequence":"additional","affiliation":[{"name":"LAETA, INEGI, Campus da FEUP, R. 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