{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T04:39:59Z","timestamp":1750307999864,"version":"3.41.0"},"reference-count":14,"publisher":"Association for Computing Machinery (ACM)","issue":"4","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":["SIGSAM Bull."],"published-print":{"date-parts":[[2005,12]]},"abstract":"<jats:p>Visual inspection can help reveal patterns that would be computationally rather difficult to reveal. We consider three different algorithms for visualizations of a DNA sequence and its nucleotide content: random walk, fractal and visualization based on the entropy-like parameters calculated using a sliding window. We present a program that uses these three methods and visualizes either the whole of a given sequence, or specified fragments. It also provides facilities to compare visualizations obtained for different sequences\/fragments. Random walk visualization considers the sequence symbol-by-symbol; the other two methods also take into account how well nucleotides are \"mixed\" in the sequence. It allows an easy visualization of repeated patterns, segments with a high\/low content of some nucleotides, such as CG-islands, etc. The program also helps to identify regions of interest for further study.<\/jats:p>","DOI":"10.1145\/1140378.1140385","type":"journal-article","created":{"date-parts":[[2007,1,17]],"date-time":"2007-01-17T18:32:02Z","timestamp":1169058722000},"page":"131-135","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["On the visualization of the DNA sequence and its nucleotide content"],"prefix":"10.1145","volume":"39","author":[{"given":"Aleksandr","family":"Myll\u00e4ri","sequence":"first","affiliation":[{"name":"University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tapio","family":"Salakoski","sequence":"additional","affiliation":[{"name":"University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexey","family":"Pasechnik","sequence":"additional","affiliation":[{"name":"University of Turku, Turku, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"320","published-online":{"date-parts":[[2005,12]]},"reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1109\/MC.2002.1016904"},{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/18.8.2163"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-0779(98)00182-9"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","unstructured":"Dan Ashlock and Jim Golden \"Evolutionary computation and fractal visualization of sequence data \" in Evolutionary Computation in Bioinformatics Gary B. Fogel and David W. Corne Eds. 2003 Morgan Kaufmann Publishers.  Dan Ashlock and Jim Golden \"Evolutionary computation and fractal visualization of sequence data \" in Evolutionary Computation in Bioinformatics Gary B. Fogel and David W. Corne Eds. 2003 Morgan Kaufmann Publishers.","DOI":"10.1016\/B978-155860797-2\/50013-5"},{"volume-title":"Springer-Verlag","year":"1992","author":"Peitgen Heinz-Otto","key":"e_1_2_1_5_1"},{"key":"e_1_2_1_6_1","unstructured":"Michael Barnsley Fractals Everywhere Morgan Kaufmann 2000.   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