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On the other hand, because of the explosive growth of information, it is difficult to manually extract the relations. In this paper we present techniques to automatically discover relations between biomedical resources from the Web. For this purpose we retrieve relevant information from Web Search engines and Pubmed database using various lexico-syntactic patterns as queries over SOAP web services. The patterns are initially handcrafted but can be progressively learnt. The extracted relations can be used to construct and augment ontologies and knowledge bases. Experiments are presented for general biomedical relation discovery and domain specific search to show the usefulness of our technique.<\/jats:p>","DOI":"10.1145\/1342320.1342323","type":"journal-article","created":{"date-parts":[[2008,4,8]],"date-time":"2008-04-08T15:40:00Z","timestamp":1207669200000},"page":"1-15","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["Discovering semantic biomedical relations utilizing the Web"],"prefix":"10.1145","volume":"2","author":[{"given":"Saurav","family":"Sahay","sequence":"first","affiliation":[{"name":"Georgia Institute of Technology, Atlanta, GA"}]},{"given":"Sougata","family":"Mukherjea","sequence":"additional","affiliation":[{"name":"IBM India Research Lab"}]},{"given":"Eugene","family":"Agichtein","sequence":"additional","affiliation":[{"name":"Emory University"}]},{"given":"Ernest V.","family":"Garcia","sequence":"additional","affiliation":[{"name":"Emory University"}]},{"given":"Shamkant B.","family":"Navathe","sequence":"additional","affiliation":[{"name":"Georgia Institute of Technology, Atlanta, GA"}]},{"given":"Ashwin","family":"Ram","sequence":"additional","affiliation":[{"name":"Georgia Institute of Technology, Atlanta, GA"}]}],"member":"320","published-online":{"date-parts":[[2008,4,3]]},"reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1145\/336597.336644"},{"volume-title":"Proceedings of the International Conference on Data Engineering (ICDE), U. 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Extracting patterns and relations from the World Wide Web . Lecture Notes in Computer Science . vol. 1590 , 172. Brin, S. 1999. Extracting patterns and relations from the World Wide Web. Lecture Notes in Computer Science. vol. 1590, 172."},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1145\/988672.988735"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1145\/1060745.1060796"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.3115\/990820.990850"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1145\/775152.775178"},{"volume-title":"Proceedings of the National Conference on Artificial Intellegence, D. L. McGuinness and G. Ferguson, Eds. The MIT Press, 391--398","author":"Etzioni O.","key":"e_1_2_1_9_1","unstructured":"Etzioni , O. , Cafarella , M. J. , Downey , D. , Popescu , A.-M. , Shaked , T. , Soderland , S. , Weld , D. S. , and Yates , A . 2004. Methods for domain-independent information extraction from the web: An experimental comparison . In Proceedings of the National Conference on Artificial Intellegence, D. L. McGuinness and G. Ferguson, Eds. The MIT Press, 391--398 . Etzioni, O., Cafarella, M. J., Downey, D., Popescu, A.-M., Shaked, T., Soderland, S., Weld, D. S., and Yates, A. 2004. Methods for domain-independent information extraction from the web: An experimental comparison. In Proceedings of the National Conference on Artificial Intellegence, D. L. McGuinness and G. Ferguson, Eds. The MIT Press, 391--398."},{"volume-title":"Proceedings of the Pacific Symposium on Biocomputing (PBS'98)","author":"Fukuda K.","key":"e_1_2_1_10_1","unstructured":"Fukuda , K. , Tsunoda , T. , Tamura , A. , and Takagi , T . 1998. Toward information extraction: Identifying protein names from biological papers . In Proceedings of the Pacific Symposium on Biocomputing (PBS'98) . Fukuda, K., Tsunoda, T., Tamura, A., and Takagi, T. 1998. Toward information extraction: Identifying protein names from biological papers. In Proceedings of the Pacific Symposium on Biocomputing (PBS'98)."},{"volume-title":"Proceedings of the FLAIRS Conference, S. M. Haller and G. Simmons, Eds. AAAI Press, 360--364","author":"Girju R.","key":"e_1_2_1_11_1","unstructured":"Girju , R. and Moldovan , D. I . 2002. Text mining for causal relations . In Proceedings of the FLAIRS Conference, S. M. Haller and G. Simmons, Eds. AAAI Press, 360--364 . Girju, R. and Moldovan, D. I. 2002. Text mining for causal relations. In Proceedings of the FLAIRS Conference, S. M. Haller and G. Simmons, Eds. AAAI Press, 360--364."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-1286(03)00225-1"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.3115\/992133.992154"},{"key":"e_1_2_1_14_1","unstructured":"Lee B. Hendler T. and Lassila J. 2001. The semantic web. Scientific Amer.  Lee B. Hendler T. and Lassila J. 2001. The semantic web. Scientific Amer."},{"volume-title":"Department of Computer and Information Science","author":"McDonald R.","key":"e_1_2_1_15_1","unstructured":"McDonald , R. 2005. Extracting relations from unstructured text. Tech. rep ., Department of Computer and Information Science , University of Pennsylvania . McDonald, R. 2005. Extracting relations from unstructured text. Tech. rep., Department of Computer and Information Science, University of Pennsylvania."},{"volume-title":"Proceedings of the Pacific Symposium on Biocomputing, R. B. Altman, T. Murray, T. E. Klein, A. K. Dunker, and L. Hunter, Eds. World Scientific, 164--175","author":"Mukherjea S.","key":"e_1_2_1_16_1","unstructured":"Mukherjea , S. and Sahay , S . 2006. Discovering biomedical relations utilizing the World Wide Web . In Proceedings of the Pacific Symposium on Biocomputing, R. B. Altman, T. Murray, T. E. Klein, A. K. Dunker, and L. Hunter, Eds. World Scientific, 164--175 . Mukherjea, S. and Sahay, S. 2006. Discovering biomedical relations utilizing the World Wide Web. In Proceedings of the Pacific Symposium on Biocomputing, R. B. Altman, T. Murray, T. E. Klein, A. K. Dunker, and L. Hunter, Eds. World Scientific, 164--175."},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1145\/956863.956941"},{"key":"e_1_2_1_18_1","volume-title":"Proceedings of the Pacific Symposium on Biocomputing, R. B. Altman, A. K. Dunker, L. Hunter, and T. E. Klein, Eds.","volume":"6","author":"Wong L.","year":"2001","unstructured":"Wong , L. 2001 . Pies, a protein interaction extraction system . In Proceedings of the Pacific Symposium on Biocomputing, R. B. Altman, A. K. Dunker, L. Hunter, and T. E. Klein, Eds. Vol. 6 . World Scientific, 520--531. Wong, L. 2001. Pies, a protein interaction extraction system. In Proceedings of the Pacific Symposium on Biocomputing, R. B. Altman, A. K. Dunker, L. Hunter, and T. E. Klein, Eds. Vol. 6. 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