{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T04:30:54Z","timestamp":1750307454675,"version":"3.41.0"},"publisher-location":"New York, NY, USA","reference-count":57,"publisher":"ACM","license":[{"start":{"date-parts":[[2010,8,2]],"date-time":"2010-08-02T00:00:00Z","timestamp":1280707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"funder":[{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["1 R01 DE17734"],"award-info":[{"award-number":["1 R01 DE17734"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2010,8,2]]},"DOI":"10.1145\/1854776.1854786","type":"proceedings-article","created":{"date-parts":[[2010,9,7]],"date-time":"2010-09-07T15:48:28Z","timestamp":1283874508000},"page":"25-34","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Relational operators for prioritizing candidate biomarkers in high-throughput differential expression data"],"prefix":"10.1145","author":[{"given":"Getiria","family":"Onsongo","sequence":"first","affiliation":[{"name":"SE, Minneapolis, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongwei","family":"Xie","sequence":"additional","affiliation":[{"name":"Mol Biology and Biophysics, Minneapolis, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Griffin","sequence":"additional","affiliation":[{"name":"Mol Biology, Minneapolis, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John V.","family":"Carlis","sequence":"additional","affiliation":[{"name":"SE, Minneapolis, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"320","published-online":{"date-parts":[[2010,8,2]]},"reference":[{"key":"e_1_3_2_1_1_1","first-page":"15","volume-title":"FQAS'2000","author":"Andreasen T.","year":"2000","unstructured":"T. Andreasen , H. Bulskov , and R. Knappe . On ontology-based querying. In Flexible query answering systems: recent advances: proceedings of the Fourth International Conference on Flexible Query Answering Systems , FQAS'2000 , October 25 --28 , 2000 , Warsaw, Poland, page 15 . Physica Verlag, 2000. T. Andreasen, H. Bulskov, and R. Knappe. On ontology-based querying. In Flexible query answering systems: recent advances: proceedings of the Fourth International Conference on Flexible Query Answering Systems, FQAS'2000, October 25--28, 2000, Warsaw, Poland, page 15. Physica Verlag, 2000."},{"key":"e_1_3_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-8-335"},{"key":"e_1_3_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04296"},{"key":"e_1_3_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-02279-1_29"},{"key":"e_1_3_2_1_5_1","volume-title":"The development of bucketing operators and a supporting operator framework for relational database management systems","author":"Bruso K.","year":"2009","unstructured":"K. Bruso . The development of bucketing operators and a supporting operator framework for relational database management systems . 2009 . K. Bruso. The development of bucketing operators and a supporting operator framework for relational database management systems. 2009."},{"key":"e_1_3_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp661"},{"key":"e_1_3_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI38079"},{"key":"e_1_3_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0900105"},{"key":"e_1_3_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1147\/rd.506.0545"},{"key":"e_1_3_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1109\/ICDE.2008.4497631"},{"key":"e_1_3_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2664"},{"key":"e_1_3_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl707"},{"key":"e_1_3_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2006-7-11-120"},{"key":"e_1_3_2_1_14_1","volume-title":"Proteomics in biomarker discovery and drug development. Journal of cellular biochemistry, 89(5):868--886","author":"He Q.","year":"2003","unstructured":"Q. He and J. Chiu . Proteomics in biomarker discovery and drug development. Journal of cellular biochemistry, 89(5):868--886 , 2003 . Q. He and J. Chiu. Proteomics in biomarker discovery and drug development. Journal of cellular biochemistry, 89(5):868--886, 2003."},{"key":"e_1_3_2_1_15_1","volume-title":"SEER cancer statistics review","author":"Horner M.","year":"1975","unstructured":"M. Horner , L. Ries , M. Krapcho , N. Neyman , R. Aminou , N. Howlader , S. Altekruse , E. Feuer , L. Huang , A. Mariotto , SEER cancer statistics review , 1975 --2006. Bethesda, MD : National Cancer Institute . (Accessed June 22, 2009, at http:\/\/seer.cancer.gov\/csr\/1975_2006.), 2009. M. Horner, L. Ries, M. Krapcho, N. Neyman, R. Aminou, N. Howlader, S. Altekruse, E. Feuer, L. Huang, A. Mariotto, et al. SEER cancer statistics review, 1975--2006. Bethesda, MD: National Cancer Institute. (Accessed June 22, 2009, at http:\/\/seer.cancer.gov\/csr\/1975_2006.), 2009."},{"key":"e_1_3_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.071852.107"},{"key":"e_1_3_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbm031"},{"key":"e_1_3_2_1_18_1","unstructured":"Keydata. Sql rank. http:\/\/www.1keydata.com\/sql\/sql-rank.html.  Keydata. Sql rank. http:\/\/www.1keydata.com\/sql\/sql-rank.html."},{"key":"e_1_3_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2008.02.013"},{"key":"e_1_3_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btg113"},{"issue":"1","key":"e_1_3_2_1_21_1","first-page":"159","article-title":"Activation of mTOR in renal cell carcinoma is due to increased phosphorylation rather than protein overexpression","volume":"23","author":"Kruck S.","year":"2010","unstructured":"S. Kruck , J. Bedke , J. Hennenlotter , P. A. Ohneseit , U. Kuehs , E. Senger , K.-D. Sievert , and A. Stenzl . Activation of mTOR in renal cell carcinoma is due to increased phosphorylation rather than protein overexpression . Oncol Rep , 23 ( 1 ): 159 -- 163 , 2010 . S. Kruck, J. Bedke, J. Hennenlotter, P. A. Ohneseit, U. Kuehs, E. Senger, K.-D. Sievert, and A. Stenzl. Activation of mTOR in renal cell carcinoma is due to increased phosphorylation rather than protein overexpression. Oncol Rep, 23(1):159--63, 2010.","journal-title":"Oncol Rep"},{"key":"e_1_3_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2907"},{"key":"e_1_3_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti1105"},{"key":"e_1_3_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568009043332709"},{"key":"e_1_3_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1109\/69.60798"},{"key":"e_1_3_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0609139104"},{"key":"e_1_3_2_1_27_1","volume-title":"An Integrative-omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer","author":"Nibbe R.","year":"2010","unstructured":"R. Nibbe , M. Koyuturk , and M. Chance . An Integrative-omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer . 2010 . R. Nibbe, M. Koyuturk, and M. Chance. An Integrative-omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer. 2010."},{"key":"e_1_3_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M800428-MCP200"},{"key":"e_1_3_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1089\/153623103322006652"},{"key":"e_1_3_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1109\/CBMS.2008.77"},{"key":"e_1_3_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2006.00708.x"},{"key":"e_1_3_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/93.14.1054"},{"key":"e_1_3_2_1_33_1","volume-title":"G2D: a tool for mining genes associated with disease. BMC Genet, 6(NIL):45","author":"Perez-Iratxeta C.","year":"2005","unstructured":"C. Perez-Iratxeta , M. Wjst , P. Bork , and M. A. Andrade . G2D: a tool for mining genes associated with disease. BMC Genet, 6(NIL):45 , 2005 . C. Perez-Iratxeta, M. Wjst, P. Bork, and M. A. Andrade. G2D: a tool for mining genes associated with disease. BMC Genet, 6(NIL):45, 2005."},{"key":"e_1_3_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2003.007641"},{"key":"e_1_3_2_1_35_1","volume-title":"Human Protein Reference Database-2009 update. Nucleic acids research","author":"Prasad T.","year":"2008","unstructured":"T. Prasad , R. Goel , K. Kandasamy , S. Keerthikumar , S. Kumar , S. Mathivanan , D. Telikicherla , R. Raju , B. Shafreen , A. Venugopal , Human Protein Reference Database-2009 update. Nucleic acids research , 2008 . T. Prasad, R. Goel, K. Kandasamy, S. Keerthikumar, S. Kumar, S. Mathivanan, D. Telikicherla, R. Raju, B. Shafreen, A. Venugopal, et al. Human Protein Reference Database-2009 update. Nucleic acids research, 2008."},{"key":"e_1_3_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-9-S9-S8"},{"key":"e_1_3_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2008.05.025"},{"key":"e_1_3_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1235"},{"key":"e_1_3_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0702507104"},{"key":"e_1_3_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature06913"},{"key":"e_1_3_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1503"},{"key":"e_1_3_2_1_42_1","first-page":"94","volume-title":"Materialization trade-offs in hierarchical shortest path algorithms. Lecture notes in computer science","author":"Shekhar S.","year":"1997","unstructured":"S. Shekhar , A. Fetterer , and B. Goyal . Materialization trade-offs in hierarchical shortest path algorithms. Lecture notes in computer science , pages 94 -- 114 , 1997 . S. Shekhar, A. Fetterer, and B. Goyal. Materialization trade-offs in hierarchical shortest path algorithms. Lecture notes in computer science, pages 94--114, 1997."},{"key":"e_1_3_2_1_43_1","volume-title":"Enabling more sophisticated gene expression analysis for understanding diseases and optimizing treatments","author":"Soh D.","year":"2007","unstructured":"D. Soh , D. Dong , Y. Guo , and L. Wong . Enabling more sophisticated gene expression analysis for understanding diseases and optimizing treatments . 2007 . D. Soh, D. Dong, Y. Guo, and L. Wong. Enabling more sophisticated gene expression analysis for understanding diseases and optimizing treatments. 2007."},{"key":"e_1_3_2_1_44_1","first-page":"1406","volume-title":"Proceedings of the 33rd international conference on Very large data bases","author":"Tata S.","year":"2007","unstructured":"S. Tata , W. Lang , and J. Patel . Periscope\/SQ: interactive exploration of biological sequence databases . In Proceedings of the 33rd international conference on Very large data bases , pages 1406 -- 1409 . VLDB Endowment , 2007 . S. Tata, W. Lang, and J. Patel. Periscope\/SQ: interactive exploration of biological sequence databases. In Proceedings of the 33rd international conference on Very large data bases, pages 1406--1409. VLDB Endowment, 2007."},{"key":"e_1_3_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1109\/SSDM.2003.1214975"},{"key":"e_1_3_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1186\/gm77"},{"key":"e_1_3_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.6.9.773"},{"key":"e_1_3_2_1_48_1","volume-title":"ENDEAVOUR update: a web resource for gene prioritization in multiple species. Nucleic Acids Res, 36(Web Server issue):W377--84","author":"Tranchevent L.-C.","year":"2008","unstructured":"L.-C. Tranchevent , R. Barriot , S. Yu , S. V. Vooren , P. V. Loo , B. Coessens , B. D. Moor , S. Aerts , and Y. Moreau . ENDEAVOUR update: a web resource for gene prioritization in multiple species. Nucleic Acids Res, 36(Web Server issue):W377--84 , 2008 . L.-C. Tranchevent, R. Barriot, S. Yu, S. V. Vooren, P. V. Loo, B. Coessens, B. D. Moor, S. Aerts, and Y. Moreau. ENDEAVOUR update: a web resource for gene prioritization in multiple species. Nucleic Acids Res, 36(Web Server issue):W377--84, 2008."},{"key":"e_1_3_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-7-31"},{"key":"e_1_3_2_1_50_1","volume-title":"GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases. Nucleic Acids Res, 33(Web Server issue):W758--61","author":"van Driel M. A.","year":"2005","unstructured":"M. A. van Driel , K. Cuelenaere , P. P. C. W. Kemmeren , J. A. M. Leunissen , H. G. Brunner , and G. Vriend . GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases. Nucleic Acids Res, 33(Web Server issue):W758--61 , 2005 . M. A. van Driel, K. Cuelenaere, P. P. C. W. Kemmeren, J. A. M. Leunissen, H. G. Brunner, and G. Vriend. GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases. Nucleic Acids Res, 33(Web Server issue):W758--61, 2005."},{"key":"e_1_3_2_1_51_1","volume-title":"Associating Genes and Protein Complexes with Disease via Network Propagation","author":"Vanunu O.","year":"2010","unstructured":"O. Vanunu , O. Magger , E. Ruppin , T. Shlomi , and R. Sharan . Associating Genes and Protein Complexes with Disease via Network Propagation . 2010 . O. Vanunu, O. Magger, E. Ruppin, T. Shlomi, and R. Sharan. Associating Genes and Protein Complexes with Disease via Network Propagation. 2010."},{"key":"e_1_3_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2007-8-3-r39"},{"key":"e_1_3_2_1_53_1","volume-title":"Network-based global inference of human disease genes. Mol Syst Biol, 4(NIL):189","author":"Wu X.","year":"2008","unstructured":"X. Wu , R. Jiang , M. Q. Zhang , and S. Li . Network-based global inference of human disease genes. Mol Syst Biol, 4(NIL):189 , 2008 . X. Wu, R. Jiang, M. Q. Zhang, and S. Li. Network-based global inference of human disease genes. Mol Syst Biol, 4(NIL):189, 2008."},{"key":"e_1_3_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.1.289"},{"key":"e_1_3_2_1_55_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M700146-MCP200"},{"key":"e_1_3_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btl467"},{"key":"e_1_3_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.010249"}],"event":{"name":"BCB'10: ACM International Conference on Bioinformatics and Computational Biology","sponsor":["SIGBio ACM Special Interest Group on Bioinformatics"],"location":"Niagara Falls New York","acronym":"BCB'10"},"container-title":["Proceedings of the First ACM International Conference on Bioinformatics and Computational Biology"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/1854776.1854786","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/1854776.1854786","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T12:08:12Z","timestamp":1750248492000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/1854776.1854786"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8,2]]},"references-count":57,"alternative-id":["10.1145\/1854776.1854786","10.1145\/1854776"],"URL":"https:\/\/doi.org\/10.1145\/1854776.1854786","relation":{},"subject":[],"published":{"date-parts":[[2010,8,2]]},"assertion":[{"value":"2010-08-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}