{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T04:31:05Z","timestamp":1750307465782,"version":"3.41.0"},"reference-count":12,"publisher":"Association for Computing Machinery (ACM)","issue":"2","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":["SIGBED Rev."],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:p>This paper describes the design and initial implementation of a modular framework for Clinical Decision Support Systems and highlights the need for medical device plug-and-play standards. The software handles the tasks of data acquisition and validation, visualization, and treatment management in order to enable the development of protocol guideline modules as \"plug-ins\" to the framework. The system utilizes an asynchronous data-driven design to support real-time information flow and user interaction. All components of the framework are modular and easily extendible, allowing for new data sources, visualization methods, and protocols to be inserted. The system is configured by assigning each protocol a manager that handles decision communication with the rest of the framework. A set of classes has been created to allow communication between the different modules along with persistence of all data, decisions, and treatments to a database. The initial prototype is a Clinical Decision Support System focusing on the treatment of Traumatic Brain Injury.<\/jats:p>","DOI":"10.1145\/1859823.1859831","type":"journal-article","created":{"date-parts":[[2010,9,22]],"date-time":"2010-09-22T11:55:58Z","timestamp":1285156558000},"page":"1-11","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["A modular framework for clinical decision support systems"],"prefix":"10.1145","volume":"6","author":[{"given":"M.","family":"Williams","sequence":"first","affiliation":[{"name":"Johns Hopkins University, Baltimore MD"}]},{"given":"F.","family":"Wu","sequence":"additional","affiliation":[{"name":"Johns Hopkins University, Baltimore MD"}]},{"given":"P.","family":"Kazanzides","sequence":"additional","affiliation":[{"name":"Johns Hopkins University, Baltimore MD"}]},{"given":"K.","family":"Brady","sequence":"additional","affiliation":[{"name":"Johns Hopkins University, Baltimore MD"}]},{"given":"J.","family":"Fackler","sequence":"additional","affiliation":[{"name":"Johns Hopkins University, Baltimore MD"}]}],"member":"320","published-online":{"date-parts":[[2009,7]]},"reference":[{"key":"e_1_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1136\/jamia.2001.0080351"},{"key":"e_1_2_1_2_1","first-page":"S1","article-title":"Guidelines for the management of severe traumatic brain injury","volume":"24","author":"Foundation Brain Trauma","journal-title":"Journal of neurotrauma"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.10.1223"},{"issue":"23","key":"e_1_2_1_4_1","first-page":"624","article-title":"The robot anaesthetist; an introduction to the automatic control of anaesthesia by means of an electro-encephalographic intermediary","volume":"76","author":"L R","year":"1952","journal-title":"Medical world"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38398.500764.8F"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","unstructured":"}}Ledley R and L Lusted. \"The Use of Electronic Computers to Aid in Medical Diagnosis.\" Proceedings of the IRE Dec 1959.  }}Ledley R and L Lusted. \"The Use of Electronic Computers to Aid in Medical Diagnosis.\" Proceedings of the IRE Dec 1959.","DOI":"10.1109\/JRPROC.1959.287213"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1950.02920130033008"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199209000-00024"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1197\/jamia.M1264"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.artmed.2008.07.006"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2008.05.003"},{"key":"e_1_2_1_12_1","doi-asserted-by":"crossref","unstructured":"}}Wu F M Kazanzides P Williams K Brady and J Fackler. \"A Modular Clinical Decision Support System: Clinical Prototype Extensible into Multiple Clinical Settings .\" Pervasive Health. London 2009.  }}Wu F M Kazanzides P Williams K Brady and J Fackler. \"A Modular Clinical Decision Support System: Clinical Prototype Extensible into Multiple Clinical Settings .\" Pervasive Health. London 2009.","DOI":"10.4108\/ICST.PERVASIVEHEALTH2009.6078"}],"container-title":["ACM SIGBED Review"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/1859823.1859831","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/1859823.1859831","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T12:08:32Z","timestamp":1750248512000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/1859823.1859831"}},"subtitle":["medical device plug-and-play is critical"],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["10.1145\/1859823.1859831"],"URL":"https:\/\/doi.org\/10.1145\/1859823.1859831","relation":{},"ISSN":["1551-3688"],"issn-type":[{"type":"electronic","value":"1551-3688"}],"subject":[],"published":{"date-parts":[[2009,7]]},"assertion":[{"value":"2009-07-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}