{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T20:23:32Z","timestamp":1773779012194,"version":"3.50.1"},"publisher-location":"New York, NY, USA","reference-count":44,"publisher":"ACM","license":[{"start":{"date-parts":[[2011,8,21]],"date-time":"2011-08-21T00:00:00Z","timestamp":1313884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,8,21]]},"DOI":"10.1145\/2020408.2020562","type":"proceedings-article","created":{"date-parts":[[2011,8,31]],"date-time":"2011-08-31T15:22:45Z","timestamp":1314804165000},"page":"931-939","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":19,"title":["Brain effective connectivity modeling for alzheimer's disease by sparse gaussian bayesian network"],"prefix":"10.1145","author":[{"given":"Shuai","family":"Huang","sequence":"first","affiliation":[{"name":"Arizona State University, Tempe, AZ, USA"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Arizona State University, Tempe, AZ, USA"}]},{"given":"Jieping","family":"Ye","sequence":"additional","affiliation":[{"name":"Arizona State University, Tempe, AZ, USA"}]},{"given":"Adam","family":"Fleisher","sequence":"additional","affiliation":[{"name":"Banner Alzheimer's Institute, Banner Good Samaritan Medical Center, Phoenix, AZ, USA"}]},{"given":"Kewei","family":"Chen","sequence":"additional","affiliation":[{"name":"Banner Alzheimer's Institute, Banner Good Samaritan Medical Center, Phoenix, AZ, USA"}]},{"given":"Teresa","family":"Wu","sequence":"additional","affiliation":[{"name":"Arizona State University, Tempe, AZ, USA"}]},{"given":"Eric","family":"Reiman","sequence":"additional","affiliation":[{"name":"Banner Alzheimer's Institute, Banner Good Samaritan Medical Center, Phoenix, AZ, USA"}]}],"member":"320","published-online":{"date-parts":[[2011,8,21]]},"reference":[{"key":"e_1_3_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-8119(03)00112-5"},{"key":"e_1_3_2_1_2_1","first-page":"101","article-title":"Patterns of Interregional Correlations of Cerebral Glucose Metabolic Rates in Patients with Dementia of the Alzheimer Type","volume":"1","author":"Azari N.","year":"1992","unstructured":"Azari , N. , Rapoport , S. 1992 . Patterns of Interregional Correlations of Cerebral Glucose Metabolic Rates in Patients with Dementia of the Alzheimer Type . Neurodegeneration 1 : 101 -- 111 . Azari, N., Rapoport, S. 1992. Patterns of Interregional Correlations of Cerebral Glucose Metabolic Rates in Patients with Dementia of the Alzheimer Type. Neurodegeneration 1: 101--111.","journal-title":"Neurodegeneration"},{"key":"e_1_3_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.460020107"},{"key":"e_1_3_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.460020108"},{"key":"e_1_3_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.1024"},{"key":"e_1_3_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.1996.0016"},{"key":"e_1_3_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1109\/ICASSP.2009.4959619"},{"key":"e_1_3_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.12.120"},{"key":"e_1_3_2_1_9_1","volume-title":"In: Ascoli","author":"Hilgetag C.","year":"2002","unstructured":"Hilgetag , C. , Kotter , R. , Stephan , K.E. and Sporns , O . 2002 . Computational Methods for the Analysis of Brain Connectivity. In: Ascoli , G.A. (Ed.), Computational Neuroanatomy. Humana Press , Totowa, NJ. Hilgetag, C., Kotter, R., Stephan, K.E. and Sporns, O. 2002. Computational Methods for the Analysis of Brain Connectivity. In: Ascoli, G.A. (Ed.), Computational Neuroanatomy. Humana Press, Totowa, NJ."},{"key":"e_1_3_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2000.0544"},{"key":"e_1_3_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-8119(03)00202-7"},{"key":"e_1_3_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-8640.1994.tb00166.x"},{"key":"e_1_3_2_1_13_1","volume-title":"UAI","author":"Friedman N.","year":"1999","unstructured":"Friedman , N. , Nachman , I. and Pe'er , D. 1999 . Learning Bayesian Network Structure from Massive Datasets: The \"Sparse Candidate\" Algorithm , UAI 1999. Friedman, N., Nachman, I. and Pe'er, D. 1999. Learning Bayesian Network Structure from Massive Datasets: The \"Sparse Candidate\" Algorithm, UAI 1999."},{"key":"e_1_3_2_1_14_1","volume-title":"AAAI","author":"Schmidt M.","year":"2007","unstructured":"Schmidt , M. , Niculescu-Mizil , A. and Murphy , K . 2007. A. Learning Graphical Model Structures using L1-Regularization Paths , AAAI 2007 . Schmidt, M., Niculescu-Mizil, A. and Murphy, K. 2007. A. Learning Graphical Model Structures using L1-Regularization Paths, AAAI 2007."},{"key":"e_1_3_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1996.tb02080.x"},{"key":"e_1_3_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10994-006-6889-7"},{"key":"e_1_3_2_1_17_1","volume-title":"NIPS","author":"Margaritis D.","year":"1999","unstructured":"Margaritis , D. and Thrun , S . 1999. Bayesian Network induction via local neighborhoods . NIPS 1999 . Margaritis, D. and Thrun, S. 1999. Bayesian Network induction via local neighborhoods. NIPS 1999."},{"key":"e_1_3_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.5555\/1390681.1442776"},{"key":"e_1_3_2_1_19_1","volume-title":"UAI","author":"Meek C.","year":"1995","unstructured":"Meek , C. 1995 . Causal inference and causal explanation with background knowledge . UAI 1995. Meek, C. 1995. Causal inference and causal explanation with background knowledge. UAI 1995."},{"key":"e_1_3_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.77.036111"},{"key":"e_1_3_2_1_21_1","unstructured":"Gill P.E. Class Notes for Math 271ABC: Numerical Optimization. Department of Mathematics UCSD. Gill P.E. Class Notes for Math 271ABC: Numerical Optimization. Department of Mathematics UCSD."},{"key":"e_1_3_2_1_22_1","volume-title":"Nonlinear Programming","unstructured":"BERTSEKAS, D. 1999. Nonlinear Programming , 2 nd Edition, Athena Scientific , Belmont . BERTSEKAS, D. 1999. Nonlinear Programming, 2nd Edition, Athena Scientific, Belmont.","edition":"2"},{"issue":"3","key":"e_1_3_2_1_23_1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1080\/10618600.1998.10474784","article-title":"Penalized Regressions: the Bridge versus the Lasso","volume":"7","author":"Fu W.","year":"1998","unstructured":"Fu , W. 1998 . Penalized Regressions: the Bridge versus the Lasso , Computational and Graphical Statistics , 7 ( 3 ), 397 -- 416 . Fu, W. 1998. Penalized Regressions: the Bridge versus the Lasso, Computational and Graphical Statistics, 7 (3), 397--416.","journal-title":"Computational and Graphical Statistics"},{"key":"e_1_3_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1214\/07-AOAS131"},{"key":"e_1_3_2_1_25_1","volume-title":"AMIA","author":"Aliferis C.","year":"2003","unstructured":"Aliferis , C. , Tsamardinos , I. and Statnikov , A . 2003. HITON, a Novel Markov Blanket Algorithm for Optimal Variable Selection . AMIA 2003 , 21--25. Aliferis, C., Tsamardinos, I. and Statnikov, A. 2003. HITON, a Novel Markov Blanket Algorithm for Optimal Variable Selection. AMIA 2003, 21--25."},{"key":"e_1_3_2_1_26_1","volume-title":"Filters and Wrappers. AISTAT","author":"Tsamardinos I.","year":"2003","unstructured":"Tsamardinos , I. and Aliferis , C . 2003. Towards Principled Feature Selection: Relevancy , Filters and Wrappers. AISTAT 2003 . Tsamardinos, I. and Aliferis, C. 2003. Towards Principled Feature Selection: Relevancy, Filters and Wrappers. AISTAT 2003."},{"key":"e_1_3_2_1_27_1","unstructured":"http:\/\/www.cs.huji.ac.il\/labs\/compbio\/Repository. http:\/\/www.cs.huji.ac.il\/labs\/compbio\/Repository."},{"key":"e_1_3_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2001.0978"},{"key":"e_1_3_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000100"},{"key":"e_1_3_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20324"},{"key":"e_1_3_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000237534.31734.1b"},{"key":"e_1_3_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002093-200607001-00010"},{"key":"e_1_3_2_1_33_1","doi-asserted-by":"crossref","unstructured":"Korb K.B. and Nicholson A.E. 2003. Bayesian Artificial Intelligence. Chapman & Hall\/CRC London UK. Korb K.B. and Nicholson A.E. 2003. Bayesian Artificial Intelligence. Chapman & Hall\/CRC London UK.","DOI":"10.1201\/9780203491294"},{"key":"e_1_3_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0308627101"},{"key":"e_1_3_2_1_35_1","first-page":"738","article-title":"Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia","volume":"159","author":"Alexander G.E.","year":"2002","unstructured":"Alexander , G.E. , Chen , K. , Pietrini , P. , Rapoport S. and Reiman , E. 2002 . Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia : A Potential Outcome Measure in AD Treatment Studies. Am.J.Psychiatry 159 , 738 -- 745 . Alexander, G.E., Chen, K., Pietrini, P., Rapoport S. and Reiman, E. 2002. Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in AD Treatment Studies. Am.J.Psychiatry 159, 738--745.","journal-title":"A Potential Outcome Measure in AD Treatment Studies. Am.J.Psychiatry"},{"key":"e_1_3_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1996.tb05866.x"},{"key":"e_1_3_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1159\/000116984"},{"key":"e_1_3_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3189-09.2009"},{"key":"e_1_3_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2007.10.038"},{"key":"e_1_3_2_1_40_1","doi-asserted-by":"crossref","unstructured":"Wu X. Li R. Fleisher A.S. Reiman E. Guan X. Zhang Y. Chen K. and Yao L. 2011. Altered Default Mode Network Connectivity in Alzheimer's Disease - A Resting Functional MRI and BN Study Human Brain Mapping in press. Wu X. Li R. Fleisher A.S. Reiman E. Guan X. Zhang Y. Chen K. and Yao L. 2011. Altered Default Mode Network Connectivity in Alzheimer's Disease - A Resting Functional MRI and BN Study Human Brain Mapping in press.","DOI":"10.1002\/hbm.21153"},{"key":"e_1_3_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn016"},{"key":"e_1_3_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20009"},{"key":"e_1_3_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2004.12.007"},{"key":"e_1_3_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1159\/000077164"}],"event":{"name":"KDD '11: The 17th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining","location":"San Diego California USA","acronym":"KDD '11","sponsor":["SIGMOD ACM Special Interest Group on Management of Data","SIGKDD ACM Special Interest Group on Knowledge Discovery in Data"]},"container-title":["Proceedings of the 17th ACM SIGKDD international conference on Knowledge discovery and data mining"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/2020408.2020562","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/2020408.2020562","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T09:48:21Z","timestamp":1750240101000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/2020408.2020562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,21]]},"references-count":44,"alternative-id":["10.1145\/2020408.2020562","10.1145\/2020408"],"URL":"https:\/\/doi.org\/10.1145\/2020408.2020562","relation":{},"subject":[],"published":{"date-parts":[[2011,8,21]]},"assertion":[{"value":"2011-08-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}