{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T03:25:25Z","timestamp":1767842725392,"version":"3.49.0"},"publisher-location":"New York, NY, USA","reference-count":70,"publisher":"ACM","license":[{"start":{"date-parts":[[2016,11,15]],"date-time":"2016-11-15T00:00:00Z","timestamp":1479168000000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"funder":[{"DOI":"10.13039\/100000015","name":"U.S. Department of Energy","doi-asserted-by":"publisher","award":["DE- AC05-00OR22725"],"award-info":[{"award-number":["DE- AC05-00OR22725"]}],"id":[{"id":"10.13039\/100000015","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["ERC-2013-ADG"],"award-info":[{"award-number":["ERC-2013-ADG"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5U01HL114476-02"],"award-info":[{"award-number":["5U01HL114476-02"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,11,15]]},"DOI":"10.1145\/2807591.2807677","type":"proceedings-article","created":{"date-parts":[[2015,10,27]],"date-time":"2015-10-27T09:07:31Z","timestamp":1445936851000},"page":"1-12","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":16,"title":["The in-silico lab-on-a-chip"],"prefix":"10.1145","author":[{"given":"Diego","family":"Rossinelli","sequence":"first","affiliation":[{"name":"ETH Z\u00fcrich, Switzerland"}]},{"given":"Yu-Hang","family":"Tang","sequence":"additional","affiliation":[{"name":"Brown University"}]},{"given":"Kirill","family":"Lykov","sequence":"additional","affiliation":[{"name":"University of Lugano"}]},{"given":"Dmitry","family":"Alexeev","sequence":"additional","affiliation":[{"name":"ETH Z\u00fcrich, Switzerland"}]},{"given":"Massimo","family":"Bernaschi","sequence":"additional","affiliation":[{"name":"CNR, Italy"}]},{"given":"Panagiotis","family":"Hadjidoukas","sequence":"additional","affiliation":[{"name":"ETH Z\u00fcrich, Switzerland"}]},{"given":"Mauro","family":"Bisson","sequence":"additional","affiliation":[{"name":"NVIDIA Corporation"}]},{"given":"Wayne","family":"Joubert","sequence":"additional","affiliation":[{"name":"Oak Ridge National Laboratory (ORNL)"}]},{"given":"Christian","family":"Conti","sequence":"additional","affiliation":[{"name":"ETH Z\u00fcrich, Switzerland"}]},{"given":"George","family":"Karniadakis","sequence":"additional","affiliation":[{"name":"Brown University"}]},{"given":"Massimiliano","family":"Fatica","sequence":"additional","affiliation":[{"name":"NVIDIA Corporation"}]},{"given":"Igor","family":"Pivkin","sequence":"additional","affiliation":[{"name":"University of Lugano"}]},{"given":"Petros","family":"Koumoutsakos","sequence":"additional","affiliation":[{"name":"ETH Z\u00fcrich, Switzerland"}]}],"member":"320","published-online":{"date-parts":[[2015,11,15]]},"reference":[{"key":"e_1_3_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpc.2012.12.003"},{"key":"e_1_3_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3820"},{"key":"e_1_3_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcp.2008.01.047"},{"key":"e_1_3_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.5555\/2789330"},{"key":"e_1_3_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.5555\/318762"},{"key":"e_1_3_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1145\/2063384.2063389"},{"key":"e_1_3_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1145\/2503210.2504563"},{"key":"e_1_3_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpc.2012.09.016"},{"key":"e_1_3_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.fluid.30.1.329"},{"key":"e_1_3_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-anchem-062011-143028"},{"key":"e_1_3_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10404-012-1073-9"},{"key":"e_1_3_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4539"},{"key":"e_1_3_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.52.1734"},{"key":"e_1_3_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2011.03.027"},{"key":"e_1_3_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/C3SM52860J"},{"key":"e_1_3_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1101210108"},{"key":"e_1_3_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcp.2007.11.009"},{"key":"e_1_3_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-fluid-010313-141349"},{"key":"e_1_3_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpc.2015.02.028"},{"key":"e_1_3_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.matsci.32.010802.112213"},{"key":"e_1_3_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-4655(99)00233-7"},{"key":"e_1_3_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.474784"},{"key":"e_1_3_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2lc40205j"},{"key":"e_1_3_2_1_24_1","volume-title":"Manag. Sci.","author":"Gusenbauer M.","year":"2011","unstructured":"M. Gusenbauer, I. Cimrak, S. Bance, L. Exl, F. Reichel, H. Oezelt, and T. Schrefl. A tunable cancer cell filter using magnetic beads: cellular and fluid dynamic simulations. Manag. Sci., 2011."},{"key":"e_1_3_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1039\/B902479B"},{"key":"e_1_3_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4SM01562B"},{"issue":"3","key":"e_1_3_2_1_27_1","first-page":"155","article-title":"Simulating microscopic hydrodynamic phenomena with dissipative particle dynamics. EPL (Europhys","volume":"19","author":"Hoogerbrugge P.","year":"1992","unstructured":"P. Hoogerbrugge and J. Koelman. Simulating microscopic hydrodynamic phenomena with dissipative particle dynamics. EPL (Europhys. Lett.), 19(3):155, 1992.","journal-title":"Lett.)"},{"key":"e_1_3_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1094567"},{"key":"e_1_3_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1039\/c0lc00595a"},{"key":"e_1_3_2_1_30_1","volume-title":"Mitsuba renderer","author":"Jakob W.","year":"2010","unstructured":"W. Jakob. Mitsuba renderer, 2010. http:\/\/www.mitsuba-renderer.org."},{"key":"e_1_3_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/mats.201100013"},{"key":"e_1_3_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2014.044"},{"key":"e_1_3_2_1_33_1","volume-title":"Microflows and nanoflows: fundamentals and simulation","author":"Karniadakis G.","year":"2005","unstructured":"G. Karniadakis, A. Beskok, and N. Aluru. Microflows and nanoflows: fundamentals and simulation, volume 29. Springer Science & Business Media, 2005."},{"key":"e_1_3_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.fluid.37.061903.175753"},{"key":"e_1_3_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-fluid-120710-101102"},{"key":"e_1_3_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1145\/1268776.1268777"},{"key":"e_1_3_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1017\/jfm.2013.91"},{"key":"e_1_3_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2011.12.006"},{"key":"e_1_3_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.104.047332"},{"key":"e_1_3_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12013-013-9702-9"},{"key":"e_1_3_2_1_41_1","volume-title":"Dept. of Statistics","author":"Marsaglia G.","year":"1993","unstructured":"G. Marsaglia and A. Zaman. The KISS generator. Technical report, Dept. of Statistics, University of Florida, 1993."},{"key":"e_1_3_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2lc21045b"},{"key":"e_1_3_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2014.82"},{"key":"e_1_3_2_1_44_1","first-page":"4","article-title":"Margination of micro- and nano-particles in blood flow and its effect on drug delivery","author":"Muller K.","year":"2014","unstructured":"K. Muller, D. Fedosov, and G. Gompper. Margination of micro- and nano-particles in blood flow and its effect on drug delivery. Sci. Rep., 4, 2014.","journal-title":"Sci. Rep."},{"key":"e_1_3_2_1_45_1","volume-title":"Emerging microfluidic devices for cell lysis: a review. Lab on a Chip, 14:1060--1073","author":"Nan L.","year":"2014","unstructured":"L. Nan, Z. Jiang, and X. Wei. Emerging microfluidic devices for cell lysis: a review. Lab on a Chip, 14:1060--1073, 2014."},{"key":"e_1_3_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-010510-103409"},{"key":"e_1_3_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.commatsci.2014.10.068"},{"issue":"1","key":"e_1_3_2_1_48_1","first-page":"10012","article-title":"Single-particle hydrodynamics in dpd: A new formulation. EPL (Europhys","volume":"84","author":"Pan W.","year":"2008","unstructured":"W. Pan, I. V. Pivkin, and G. E. Karniadakis. Single-particle hydrodynamics in dpd: A new formulation. EPL (Europhys. Lett.), 84(1):10012, 2008.","journal-title":"Lett.)"},{"key":"e_1_3_2_1_49_1","first-page":"06","volume-title":"Oncogene","author":"Pantel K.","year":"2015","unstructured":"K. Pantel and M. R. Speicher. The biology of circulating tumor cells. Oncogene, pages --, 06 2015."},{"key":"e_1_3_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1311827110"},{"key":"e_1_3_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcp.2011.05.021"},{"key":"e_1_3_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13206-013-7408-0"},{"key":"e_1_3_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.101.118105"},{"key":"e_1_3_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1006\/jcph.1995.1039"},{"key":"e_1_3_2_1_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-010-0232-y"},{"key":"e_1_3_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1109\/SC.2010.42"},{"key":"e_1_3_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3681"},{"key":"e_1_3_2_1_58_1","volume-title":"splitting force updates to reduce computational work. Structure, 9(4)","author":"Schlick T.","year":"2001","unstructured":"T. Schlick. Time-trimming tricks for dynamic simulations: splitting force updates to reduce computational work. Structure, 9(4), 2001."},{"key":"e_1_3_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1103\/RevModPhys.77.977"},{"key":"e_1_3_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10404-008-0375-4"},{"key":"e_1_3_2_1_61_1","volume-title":"Chip in a lab: Microfluidics for next generation life science research. Biomicrofluidics, 7(1)","author":"Streets A.","year":"2013","unstructured":"A. Streets and Y. Huang. Chip in a lab: Microfluidics for next generation life science research. Biomicrofluidics, 7(1), 2013."},{"key":"e_1_3_2_1_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpc.2014.06.015"},{"key":"e_1_3_2_1_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcp.2004.11.020"},{"key":"e_1_3_2_1_64_1","first-page":"922","volume-title":"Proc. of the Annual Conf. on Communication Control and Computing","volume":"30","author":"Wagner N.","year":"1992","unstructured":"N. Wagner. The logistic lattice in random number generation. In Proc. of the Annual Conf. on Communication Control and Computing, volume 30, pages 922--922. University of Illinois, 1992."},{"key":"e_1_3_2_1_65_1","doi-asserted-by":"publisher","DOI":"10.3233\/BME-130833"},{"key":"e_1_3_2_1_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-60590-8_29"},{"key":"e_1_3_2_1_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05058"},{"key":"e_1_3_2_1_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2013.05.010"},{"key":"e_1_3_2_1_69_1","volume-title":"Micromagnetic-microfluidic blood cleansing device. Lab on a Chip, 9:1171--1177","author":"Yung C.","year":"2009","unstructured":"C. Yung, J. Fiering, A. Mueller, and D. Ingber. Micromagnetic-microfluidic blood cleansing device. Lab on a Chip, 9:1171--1177, 2009."},{"key":"e_1_3_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcp.2015.01.004"}],"event":{"name":"SC15: The International Conference for High Performance Computing, Networking, Storage and Analysis","location":"Austin Texas","acronym":"SC15","sponsor":["SIGHPC ACM Special Interest Group on High Performance Computing, Special Interest Group on High Performance Computing","SIGARCH ACM Special Interest Group on Computer Architecture","IEEE-CS Computer Society"]},"container-title":["Proceedings of the International Conference for High Performance Computing, Networking, Storage and Analysis"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/2807591.2807677","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/2807591.2807677","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/2807591.2807677","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T09:44:11Z","timestamp":1763459051000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/2807591.2807677"}},"subtitle":["petascale and high-throughput simulations of microfluidics at cell resolution"],"short-title":[],"issued":{"date-parts":[[2015,11,15]]},"references-count":70,"alternative-id":["10.1145\/2807591.2807677","10.1145\/2807591"],"URL":"https:\/\/doi.org\/10.1145\/2807591.2807677","relation":{},"subject":[],"published":{"date-parts":[[2015,11,15]]},"assertion":[{"value":"2015-11-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}