{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T04:28:39Z","timestamp":1750220919608,"version":"3.41.0"},"publisher-location":"New York, NY, USA","reference-count":34,"publisher":"ACM","license":[{"start":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T00:00:00Z","timestamp":1571788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,10,23]]},"DOI":"10.1145\/3369166.3369169","type":"proceedings-article","created":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T04:20:27Z","timestamp":1578975627000},"page":"73-79","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Genome-wide Association of APOE and FOXO3A for human longevity"],"prefix":"10.1145","author":[{"given":"Birga Anteneh","family":"Mengesha","sequence":"first","affiliation":[{"name":"University of Electronics Science and Technology, Qingshuihe Campus, Chengdu"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huang","family":"Jian","sequence":"additional","affiliation":[{"name":"University of Electronics Science and Technology, Qingshuihe Campus, Chengdu"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"320","published-online":{"date-parts":[[2020,1,13]]},"reference":[{"key":"e_1_3_2_1_1_1","doi-asserted-by":"crossref","unstructured":"Aladdin H. Shadyab Charles Kooperberg. 2016. Replication of Genome-Wide Association Study Findings of Longevity in White African American and Hispanic women. Journals of Gerontology. Doi: 10.1093\/gerona\/glw198.  Aladdin H. Shadyab Charles Kooperberg. 2016. Replication of Genome-Wide Association Study Findings of Longevity in White African American and Hispanic women. Journals of Gerontology. Doi: 10.1093\/gerona\/glw198.","DOI":"10.1093\/gerona\/glw198"},{"key":"e_1_3_2_1_2_1","doi-asserted-by":"crossref","unstructured":"Alberto Montesanto. 2012. Epidemiological genetic and epigenetic aspects of the research on healthy ageing and longevity. Biomedical center.  Alberto Montesanto. 2012. Epidemiological genetic and epigenetic aspects of the research on healthy ageing and longevity. Biomedical center.","DOI":"10.1186\/1742-4933-9-6"},{"key":"e_1_3_2_1_3_1","doi-asserted-by":"crossref","unstructured":"Almut Nebel Rabea Kleindorp Make Caliebe. 2011. A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals. Doi: 10.1016\/j.mad.2011.06.008.  Almut Nebel Rabea Kleindorp Make Caliebe. 2011. A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals. Doi: 10.1016\/j.mad.2011.06.008.","DOI":"10.1016\/j.mad.2011.06.008"},{"key":"e_1_3_2_1_4_1","volume-title":"et al","author":"Capurso C.","year":"2004","unstructured":"Capurso , C. et al . 2004 . Interleukin 6-174G\/C promoter gene polymorphism in centenarians: no evidence of association with human longevity or interaction with apolipoprotein E alleles. 39, 1109--1114. Doi :10.1016\/j.exger.2004.03.037 Capurso, C. et al. 2004. Interleukin 6-174G\/C promoter gene polymorphism in centenarians: no evidence of association with human longevity or interaction with apolipoprotein E alleles. 39, 1109--1114. Doi:10.1016\/j.exger.2004.03.037"},{"key":"e_1_3_2_1_5_1","doi-asserted-by":"crossref","unstructured":"Chiara Viviani Anselmi Alberto Malovini Roberta Roncarati 2009. Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study. Doi: 10.1089\/rej.2008.0827.  Chiara Viviani Anselmi Alberto Malovini Roberta Roncarati 2009. Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study. Doi: 10.1089\/rej.2008.0827.","DOI":"10.1089\/rej.2008.0827"},{"key":"e_1_3_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1871"},{"key":"e_1_3_2_1_7_1","doi-asserted-by":"crossref","unstructured":"Deelen J Beekman M Uh HW etal 2011. Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited. Aging Cell. 2011; 10(4):686--698. Doi: 10.1111\/j.1474-9726.2011.00705.x  Deelen J Beekman M Uh HW et al. 2011. Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited. Aging Cell. 2011; 10(4):686--698. Doi: 10.1111\/j.1474-9726.2011.00705.x","DOI":"10.1111\/j.1474-9726.2011.00705.x"},{"key":"e_1_3_2_1_8_1","volume-title":"Complex Diseases: Analysis of Single-Nucleotide Polymorphisms around APOE in Alzheimer Disease. Spring er 383--394. https:\/\/doi.org\/10.1086\/303003","author":"Eden R.","year":"2000","unstructured":"Eden R. Martin et al. 2000 . Away at Complex Diseases: Analysis of Single-Nucleotide Polymorphisms around APOE in Alzheimer Disease. Spring er 383--394. https:\/\/doi.org\/10.1086\/303003 10.1086\/303003 Eden R.Martin et al. 2000. Away at Complex Diseases: Analysis of Single-Nucleotide Polymorphisms around APOE in Alzheimer Disease. Spring er 383--394. https:\/\/doi.org\/10.1086\/303003"},{"key":"e_1_3_2_1_9_1","volume-title":"Genetic variation in insulin\/IGF-1 signaling pathways and longevity","author":"Elad Ziv Donglei Hu","year":"2010","unstructured":"Elad Ziv Donglei Hu . 2011. Genetic variation in insulin\/IGF-1 signaling pathways and longevity . Elsevier . https:\/\/doi.org\/10.1016\/j.arr. 2010 .09.002 10.1016\/j.arr.2010.09.002 Elad Ziv Donglei Hu. 2011. Genetic variation in insulin\/IGF-1 signaling pathways and longevity. Elsevier. https:\/\/doi.org\/10.1016\/j.arr.2010.09.002"},{"key":"e_1_3_2_1_10_1","first-page":"343","article-title":"Is APOE &epsiv;3 a favourable factor for the longevity: an association study in Chinese population J","volume":"90","author":"Feng J.","year":"2011","unstructured":"Feng , J. 2011 . Is APOE &epsiv;3 a favourable factor for the longevity: an association study in Chinese population J . Genet. 90 , 343 -- 347 . Doi: 10.1007\/s12041-011-0075-9 Feng, J. et al. 2011. Is APOE &epsiv;3 a favourable factor for the longevity: an association study in Chinese population J. Genet. 90, 343--347. Doi: 10.1007\/s12041-011-0075-9","journal-title":"Genet."},{"key":"e_1_3_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0809594106"},{"key":"e_1_3_2_1_12_1","volume-title":"Xiang Liu et al","author":"Guodong Liu","year":"2017","unstructured":"Guodong Liu , Xiang Liu et al . 2017 . APOE gene polymorphism in long-lived individuals from a central China population. https:\/\/doi.org\/10.1038\/s41598-017-03227-5 10.1038\/s41598-017-03227-5 Guodong Liu, Xiang Liu et al. 2017. APOE gene polymorphism in long-lived individuals from a central China population. https:\/\/doi.org\/10.1038\/s41598-017-03227-5"},{"volume-title":"1996","author":"Herskind","key":"e_1_3_2_1_13_1","unstructured":"Herskind et al. 1996 . Springer . The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900;97: 319--323 Herskind et al.1996. Springer. The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900;97: 319--323"},{"key":"e_1_3_2_1_14_1","volume-title":"Ivan Iachine et al","author":"Jacob B.","year":"2006","unstructured":"Jacob v B. Hjelmborg , Ivan Iachine et al . 2006 . Genetic influence on human lifespan and longevity. DOI 10.1007\/s00439-006-0144-y Jacob vB. Hjelmborg, Ivan Iachine et al. 2006. Genetic influence on human lifespan and longevity. DOI 10.1007\/s00439-006-0144-y"},{"volume-title":"Biodemography of human ageing. Nature 25","author":"James W.","key":"e_1_3_2_1_15_1","unstructured":"James W. Vaupel . 201 0. Biodemography of human ageing. Nature 25 ; 464 (7288): 536--44. Doi : 10.1038\/nature08984. James W. Vaupel. 2010. Biodemography of human ageing. Nature 25; 464 (7288): 536--44. Doi: 10.1038\/nature08984."},{"key":"e_1_3_2_1_16_1","volume-title":"Murabito et al","author":"Joanne M.","year":"2012","unstructured":"Joanne M. Murabito et al . 2012 . The Search for Longevity and Healthy Aging Genes: Insights from Epidemiological Studies and Samples of Long-Lived Individuals . Joanne M. Murabito et al. 2012. The Search for Longevity and Healthy Aging Genes: Insights from Epidemiological Studies and Samples of Long-Lived Individuals."},{"key":"e_1_3_2_1_17_1","volume-title":"Xiao Dong et al","author":"Johnson","year":"2015","unstructured":"Johnson , Xiao Dong et al . 2015 . Genetic evidence for common pathways in human age-related Diseases. Doi : 10.1111\/acel.12362 Johnson, Xiao Dong et al. 2015. Genetic evidence for common pathways in human age-related Diseases. Doi: 10.1111\/acel.12362"},{"key":"e_1_3_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201766"},{"key":"e_1_3_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp459"},{"key":"e_1_3_2_1_20_1","volume-title":"Buchman et al","author":"Linda Broer S.","year":"2014","unstructured":"Linda Broer , Aron S. Buchman et al , 2014 . GWAS of longevity in CHARGE consortium. The journals of Geronotology . https:\/\/doi.org\/10.1093\/gerona\/glu166 10.1093\/gerona Linda Broer, Aron S. Buchman et al, 2014. GWAS of longevity in CHARGE consortium. The journals of Geronotology. https:\/\/doi.org\/10.1093\/gerona\/glu166"},{"key":"e_1_3_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2001.49199.x"},{"key":"e_1_3_2_1_22_1","volume-title":"Rall SC Jr","author":"Mahley RW","year":"2000","unstructured":"Mahley RW , Rall SC Jr . 2000 . Apolipoprotein E: far more than a lipid transport protein. Annu Rev genomics Hum Genet 1: 507--37. DOI:10.1146\/annurev.genom.1.1.507 10.1146\/annurev.genom.1.1.507 Mahley RW, Rall SC Jr. 2000. Apolipoprotein E: far more than a lipid transport protein. Annu Rev genomics Hum Genet 1: 507--37. DOI:10.1146\/annurev.genom.1.1.507"},{"key":"e_1_3_2_1_23_1","doi-asserted-by":"crossref","unstructured":"Marian Beekman Helen Blanche. 2013. Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study. Doi: 10.1111\/acel.12039.  Marian Beekman Helen Blanche. 2013. Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study. Doi: 10.1111\/acel.12039.","DOI":"10.1111\/acel.12039"},{"key":"e_1_3_2_1_24_1","doi-asserted-by":"crossref","unstructured":"Mette Soerensen. 2014. Association study of FOXO3A SNPs and aging phenotypes in Danish oldest-old individuals. Doi: 10.1111\/acel.12295  Mette Soerensen. 2014. Association study of FOXO3A SNPs and aging phenotypes in Danish oldest-old individuals. Doi: 10.1111\/acel.12295","DOI":"10.1111\/acel.12295"},{"key":"e_1_3_2_1_25_1","doi-asserted-by":"crossref","unstructured":"Miriam Capri Stefano Salvioli. 2006. The Genetics of Human Longevity. Doi: 10.1196\/annals.1354.033  Miriam Capri Stefano Salvioli. 2006. The Genetics of Human Longevity. Doi: 10.1196\/annals.1354.033","DOI":"10.1196\/annals.1354.033"},{"key":"e_1_3_2_1_26_1","volume-title":"Torben Martinussen et al","author":"Rune Jacobsen","year":"2010","unstructured":"Rune Jacobsen , Torben Martinussen et al . 2010 . Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies. Doi : 10.1111\/j.1474-9726.2010.00626.x Rune Jacobsen, Torben Martinussen et al. 2010. Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies. Doi: 10.1111\/j.1474-9726.2010.00626.x"},{"key":"e_1_3_2_1_27_1","doi-asserted-by":"crossref","unstructured":"Rute Martins Gordon J. Lithgow2 and Wolfgang. 2015. Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. Doi: 10.1111\/acel.12427  Rute Martins Gordon J. Lithgow2 and Wolfgang. 2015. Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. Doi: 10.1111\/acel.12427","DOI":"10.1111\/acel.12427"},{"key":"e_1_3_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0194-29"},{"key":"e_1_3_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2010.00627.x"},{"key":"e_1_3_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2190"},{"key":"e_1_3_2_1_31_1","doi-asserted-by":"crossref","unstructured":"Visscher PM Brown MA etal 2012. Five years of GWAS discovery. Annu Rev genomics Hum Genet 90 (1): 7--24. Doi: 10.1016\/j.ajhg.2011.11.029.  Visscher PM Brown MA et al. 2012. Five years of GWAS discovery. Annu Rev genomics Hum Genet 90 (1): 7--24. Doi: 10.1016\/j.ajhg.2011.11.029.","DOI":"10.1016\/j.ajhg.2011.11.029"},{"key":"e_1_3_2_1_32_1","unstructured":"Walter et al. 2011. A genome-wide association study of aging Stefan Waltera b 1 Gil Atzmonc d e 1 Elsevier Inc.  Walter et al. 2011. A genome-wide association study of aging Stefan Waltera b 1 Gil Atzmonc d e 1 Elsevier Inc."},{"volume-title":"Proc Natl Acad Sci U S A; 105(37)","author":"Willcox BJ","key":"e_1_3_2_1_33_1","unstructured":"Willcox BJ , Donlon TA , He Q , 2008. FOXO3A genotype is strongly associated with human longevity . Proc Natl Acad Sci U S A; 105(37) :13987--13992. Doi : 10.1073\/pnas.0801030105. Willcox BJ, Donlon TA, He Q, et al. 2008. FOXO3A genotype is strongly associated with human longevity. Proc Natl Acad Sci U S A; 105(37):13987--13992. Doi: 10.1073\/pnas.0801030105."},{"key":"e_1_3_2_1_34_1","volume-title":"Lingguo Cheng et al","author":"Yi Zeng","year":"2010","unstructured":"Yi Zeng , Lingguo Cheng et al . 2010 . Effects of FOXO Genotypes on Longevity : A Biodemographic Analysis. Doi : 10.1093\/gerona\/glq156 Yi Zeng, Lingguo Cheng et al. 2010. Effects of FOXO Genotypes on Longevity: A Biodemographic Analysis. Doi: 10.1093\/gerona\/glq156"}],"event":{"name":"ICBBS 2019: 2019 8th International Conference on Bioinformatics and Biomedical Science","sponsor":["Beijing University of Technology","Harbin Inst. Technol. Harbin Institute of Technology"],"location":"Beijing China","acronym":"ICBBS 2019"},"container-title":["Proceedings of the 2019 8th International Conference on Bioinformatics and Biomedical Science"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3369166.3369169","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/3369166.3369169","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T23:53:06Z","timestamp":1750204386000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3369166.3369169"}},"subtitle":["A Systematic Review"],"short-title":[],"issued":{"date-parts":[[2019,10,23]]},"references-count":34,"alternative-id":["10.1145\/3369166.3369169","10.1145\/3369166"],"URL":"https:\/\/doi.org\/10.1145\/3369166.3369169","relation":{},"subject":[],"published":{"date-parts":[[2019,10,23]]},"assertion":[{"value":"2020-01-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}