{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T04:21:25Z","timestamp":1750220485170,"version":"3.41.0"},"publisher-location":"New York, NY, USA","reference-count":52,"publisher":"ACM","license":[{"start":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T00:00:00Z","timestamp":1635465600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,10,29]]},"DOI":"10.1145\/3498731.3498757","type":"proceedings-article","created":{"date-parts":[[2022,1,26]],"date-time":"2022-01-26T16:18:17Z","timestamp":1643213897000},"page":"162-167","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["A review of Colorectal Cancer and Intestinal Microbiota"],"prefix":"10.1145","author":[{"given":"Jamie Shengwei","family":"Tian","sequence":"first","affiliation":[{"name":"Canford Magna, Canford School, UK"}]}],"member":"320","published-online":{"date-parts":[[2022,1,26]]},"reference":[{"key":"e_1_3_2_1_1_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21590"},{"key":"e_1_3_2_1_2_1","doi-asserted-by":"crossref","unstructured":"Shtivelman E. Lifshitz B. Gale R. and Canaani E. 1985. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia.\u00a0Nature 315(6020) pp.550-554.  Shtivelman E. Lifshitz B. Gale R. and Canaani E. 1985. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia.\u00a0Nature 315(6020) pp.550-554.","DOI":"10.1038\/315550a0"},{"key":"e_1_3_2_1_3_1","doi-asserted-by":"crossref","unstructured":"Matlashewski G. Lamb P. Pim D. Peacock J. Crawford L. and Benchimol S. 1984. Isolation and characterization of a human p53 cDNA clone: expression of the human p53 gene.\u00a0The EMBO Journal 3(13) pp.3257-3262.  Matlashewski G. Lamb P. Pim D. Peacock J. Crawford L. and Benchimol S. 1984. Isolation and characterization of a human p53 cDNA clone: expression of the human p53 gene.\u00a0The EMBO Journal 3(13) pp.3257-3262.","DOI":"10.1002\/j.1460-2075.1984.tb02287.x"},{"key":"e_1_3_2_1_4_1","doi-asserted-by":"crossref","unstructured":"Hassanpour S. and Dehghani M. 2017. Review of cancer from perspective of molecular.\u00a0Journal of Cancer Research and Practice 4(4) pp.127-129.  Hassanpour S. and Dehghani M. 2017. Review of cancer from perspective of molecular.\u00a0Journal of Cancer Research and Practice 4(4) pp.127-129.","DOI":"10.1016\/j.jcrpr.2017.07.001"},{"key":"e_1_3_2_1_5_1","volume-title":"Hallmarks of Cancer: The Next Generation.\u00a0Yearbook of Anesthesiology and Pain Management","author":"Roizen M.","year":"2012","unstructured":"Roizen , M. , 2012. Hallmarks of Cancer: The Next Generation.\u00a0Yearbook of Anesthesiology and Pain Management , 2012 , p.13. Roizen, M., 2012. Hallmarks of Cancer: The Next Generation.\u00a0Yearbook of Anesthesiology and Pain Management, 2012, p.13."},{"key":"e_1_3_2_1_6_1","doi-asserted-by":"crossref","unstructured":"Fan Y. and Pedersen O. 2020. Gut microbiota in human metabolic health and disease.\u00a0Nature Reviews Microbiology 19(1) pp.55-71.  Fan Y. and Pedersen O. 2020. Gut microbiota in human metabolic health and disease.\u00a0Nature Reviews Microbiology 19(1) pp.55-71.","DOI":"10.1038\/s41579-020-0433-9"},{"key":"e_1_3_2_1_7_1","doi-asserted-by":"crossref","unstructured":"Wastyk H. Fragiadakis G. Perelman D. Dahan D. Merrill B. Yu F. Topf M. Gonzalez C. Van Treuren W. Han S. Robinson J. Elias J. Sonnenburg E. Gardner C. and Sonnenburg J. 2021. Gut-microbiota-targeted diets modulate human immune status.\u00a0Cell .  Wastyk H. Fragiadakis G. Perelman D. Dahan D. Merrill B. Yu F. Topf M. Gonzalez C. Van Treuren W. Han S. Robinson J. Elias J. Sonnenburg E. Gardner C. and Sonnenburg J. 2021. Gut-microbiota-targeted diets modulate human immune status.\u00a0Cell .","DOI":"10.1101\/2020.09.30.321448"},{"key":"e_1_3_2_1_8_1","doi-asserted-by":"crossref","unstructured":"Gill S. Pop M. DeBoy R. Eckburg P. Turnbaugh P. Samuel B. Gordon J. Relman D. Fraser-Liggett C. and Nelson K. 2006. Metagenomic Analysis of the Human Distal Gut Microbiome.\u00a0Science 312(5778) pp.1355-1359.  Gill S. Pop M. DeBoy R. Eckburg P. Turnbaugh P. Samuel B. Gordon J. Relman D. Fraser-Liggett C. and Nelson K. 2006. Metagenomic Analysis of the Human Distal Gut Microbiome.\u00a0Science 312(5778) pp.1355-1359.","DOI":"10.1126\/science.1124234"},{"key":"e_1_3_2_1_9_1","doi-asserted-by":"crossref","unstructured":"Tsai Y. Lin T. Chang C. Wu T. Lai W. Lu C. and Lai H. 2019. Probiotics prebiotics and amelioration of diseases.\u00a0Journal of Biomedical Science 26(1).  Tsai Y. Lin T. Chang C. Wu T. Lai W. Lu C. and Lai H. 2019. Probiotics prebiotics and amelioration of diseases.\u00a0Journal of Biomedical Science 26(1).","DOI":"10.1186\/s12929-018-0493-6"},{"key":"e_1_3_2_1_10_1","doi-asserted-by":"crossref","unstructured":"Cheng Y. Ling Z. and Li L. 2020. The Intestinal Microbiota and Colorectal Cancer.\u00a0Frontiers in Immunology 11.  Cheng Y. Ling Z. and Li L. 2020. The Intestinal Microbiota and Colorectal Cancer.\u00a0Frontiers in Immunology 11.","DOI":"10.3389\/fimmu.2020.615056"},{"key":"e_1_3_2_1_11_1","doi-asserted-by":"crossref","unstructured":"Chen W. Liu F. Ling Z. Tong X. and Xiang C. 2012. Human Intestinal Lumen and Mucosa-Associated Microbiota in Patients with Colorectal Cancer.\u00a0PLoS ONE 7(6) p.e39743.  Chen W. Liu F. Ling Z. Tong X. and Xiang C. 2012. Human Intestinal Lumen and Mucosa-Associated Microbiota in Patients with Colorectal Cancer.\u00a0PLoS ONE 7(6) p.e39743.","DOI":"10.1371\/journal.pone.0039743"},{"key":"e_1_3_2_1_12_1","doi-asserted-by":"crossref","unstructured":"Luan C. Xie L. Yang X. Miao H. Lv N. Zhang R. Xiao X. Hu Y. Liu Y. Wu N. Zhu Y. and Zhu B. 2015. Dysbiosis of Fungal Microbiota in the Intestinal Mucosa of Patients with Colorectal Adenomas.\u00a0Scientific Reports 5(1).  Luan C. Xie L. Yang X. Miao H. Lv N. Zhang R. Xiao X. Hu Y. Liu Y. Wu N. Zhu Y. and Zhu B. 2015. Dysbiosis of Fungal Microbiota in the Intestinal Mucosa of Patients with Colorectal Adenomas.\u00a0Scientific Reports 5(1).","DOI":"10.1038\/srep07980"},{"key":"e_1_3_2_1_13_1","doi-asserted-by":"crossref","unstructured":"Boleij A. van Gelder M. Swinkels D. and Tjalsma H. 2011. Clinical Importance of Streptococcus gallolyticus Infection Among Colorectal Cancer Patients: Systematic Review and Meta-analysis.\u00a0Clinical Infectious Diseases 53(9) pp.870-878.  Boleij A. van Gelder M. Swinkels D. and Tjalsma H. 2011. Clinical Importance of Streptococcus gallolyticus Infection Among Colorectal Cancer Patients: Systematic Review and Meta-analysis.\u00a0Clinical Infectious Diseases 53(9) pp.870-878.","DOI":"10.1093\/cid\/cir609"},{"key":"e_1_3_2_1_14_1","doi-asserted-by":"crossref","unstructured":"Chung L. Thiele Orberg E. Geis A. Chan J. Fu K. DeStefano Shields C. Dejea C. Fathi P. Chen J. Finard B. Tam A. McAllister F. Fan H. Wu X. Ganguly S. Lebid A. Metz P. Van Meerbeke S. Huso D. Wick E. Pardoll D. Wan F. Wu S. Sears C. and Housseau F. 2018. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.\u00a0Cell Host & Microbe 23(2) pp.203-214.e5.  Chung L. Thiele Orberg E. Geis A. Chan J. Fu K. DeStefano Shields C. Dejea C. Fathi P. Chen J. Finard B. Tam A. McAllister F. Fan H. Wu X. Ganguly S. Lebid A. Metz P. Van Meerbeke S. Huso D. Wick E. Pardoll D. Wan F. Wu S. Sears C. and Housseau F. 2018. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.\u00a0Cell Host & Microbe 23(2) pp.203-214.e5.","DOI":"10.1016\/j.chom.2018.01.007"},{"key":"e_1_3_2_1_15_1","doi-asserted-by":"crossref","unstructured":"Kostic A. Chun E. Robertson L. Glickman J. Gallini C. Michaud M. Clancy T. Chung D. Lochhead P. Hold G. El-Omar E. Brenner D. Fuchs C. Meyerson M. and Garrett W. 2013. Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment.\u00a0Cell Host & Microbe 14(2) pp.207-215.  Kostic A. Chun E. Robertson L. Glickman J. Gallini C. Michaud M. Clancy T. Chung D. Lochhead P. Hold G. El-Omar E. Brenner D. Fuchs C. Meyerson M. and Garrett W. 2013. Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment.\u00a0Cell Host & Microbe 14(2) pp.207-215.","DOI":"10.1016\/j.chom.2013.07.007"},{"key":"e_1_3_2_1_16_1","doi-asserted-by":"crossref","unstructured":"Bashir A. Miskeen A. Bhat A. Fazili K. and Ganai B. 2015. Fusobacterium nucleatum.\u00a0European Journal of Cancer Prevention 24(5) pp.373-385.  Bashir A. Miskeen A. Bhat A. Fazili K. and Ganai B. 2015. Fusobacterium nucleatum.\u00a0European Journal of Cancer Prevention 24(5) pp.373-385.","DOI":"10.1097\/CEJ.0000000000000116"},{"key":"e_1_3_2_1_17_1","doi-asserted-by":"crossref","unstructured":"Liu X. Cheng Y. Shao L. and Ling Z. 2020. Alterations of the Predominant Fecal Microbiota and Disruption of the Gut Mucosal Barrier in Patients with Early-Stage Colorectal Cancer.\u00a0BioMed Research International 2020 pp.1-8.  Liu X. Cheng Y. Shao L. and Ling Z. 2020. Alterations of the Predominant Fecal Microbiota and Disruption of the Gut Mucosal Barrier in Patients with Early-Stage Colorectal Cancer.\u00a0BioMed Research International 2020 pp.1-8.","DOI":"10.1155\/2020\/2948282"},{"key":"e_1_3_2_1_18_1","doi-asserted-by":"crossref","unstructured":"Veziant J. Gagni\u00e8re J. Jouberton E. Bonnin V. Sauvanet P. Pezet D. Barnich N. Miot-Noirault E. and Bonnet M. 2016. Association of colorectal cancer with pathogenicEscherichia coli: Focus on mechanisms using optical imaging.\u00a0World Journal of Clinical Oncology 7(3) p.293.  Veziant J. Gagni\u00e8re J. Jouberton E. Bonnin V. Sauvanet P. Pezet D. Barnich N. Miot-Noirault E. and Bonnet M. 2016. Association of colorectal cancer with pathogenicEscherichia coli: Focus on mechanisms using optical imaging.\u00a0World Journal of Clinical Oncology 7(3) p.293.","DOI":"10.5306\/wjco.v7.i3.293"},{"key":"e_1_3_2_1_19_1","doi-asserted-by":"crossref","unstructured":"Wang T. Cai G. Qiu Y. Fei N. Zhang M. Pang X. Jia W. Cai S. and Zhao L. 2011. Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers.\u00a0The ISME Journal 6(2) pp.320-329.  Wang T. Cai G. Qiu Y. Fei N. Zhang M. Pang X. Jia W. Cai S. and Zhao L. 2011. Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers.\u00a0The ISME Journal 6(2) pp.320-329.","DOI":"10.1038\/ismej.2011.109"},{"key":"e_1_3_2_1_20_1","doi-asserted-by":"crossref","unstructured":"Wang X. Allen T. May R. Lightfoot S. Houchen C. and Huycke M. 2008. Enterococcus faecalis Induces Aneuploidy and Tetraploidy in Colonic Epithelial Cells through a Bystander Effect.\u00a0Cancer Research 68(23) pp.9909-9917.  Wang X. Allen T. May R. Lightfoot S. Houchen C. and Huycke M. 2008. Enterococcus faecalis Induces Aneuploidy and Tetraploidy in Colonic Epithelial Cells through a Bystander Effect.\u00a0Cancer Research 68(23) pp.9909-9917.","DOI":"10.1158\/0008-5472.CAN-08-1551"},{"key":"e_1_3_2_1_21_1","doi-asserted-by":"crossref","unstructured":"Rubinstein M. Wang X. Liu W. Hao Y. Cai G. and Han Y. 2013. Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin\/\u03b2-Catenin Signaling via its FadA Adhesin.\u00a0Cell Host & Microbe 14(2) pp.195-206.  Rubinstein M. Wang X. Liu W. Hao Y. Cai G. and Han Y. 2013. Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin\/\u03b2-Catenin Signaling via its FadA Adhesin.\u00a0Cell Host & Microbe 14(2) pp.195-206.","DOI":"10.1016\/j.chom.2013.07.012"},{"key":"e_1_3_2_1_22_1","doi-asserted-by":"crossref","unstructured":"Gur C. Ibrahim Y. Isaacson B. Yamin R. Abed J. Gamliel M. Enk J. Bar-On Y. Stanietsky-Kaynan N. Coppenhagen-Glazer S. Shussman N. Almogy G. Cuapio A. Hofer E. Mevorach D. Tabib A. Ortenberg R. Markel G. Mikli\u0107 K. Jonjic S. Brennan C. Garrett W. Bachrach G. and Mandelboim O. 2015. Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack.\u00a0Immunity 42(2) pp.344-355.  Gur C. Ibrahim Y. Isaacson B. Yamin R. Abed J. Gamliel M. Enk J. Bar-On Y. Stanietsky-Kaynan N. Coppenhagen-Glazer S. Shussman N. Almogy G. Cuapio A. Hofer E. Mevorach D. Tabib A. Ortenberg R. Markel G. Mikli\u0107 K. Jonjic S. Brennan C. Garrett W. Bachrach G. and Mandelboim O. 2015. Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack.\u00a0Immunity 42(2) pp.344-355.","DOI":"10.1016\/j.immuni.2015.01.010"},{"key":"e_1_3_2_1_23_1","doi-asserted-by":"crossref","unstructured":"Casasanta M. Yoo C. Udayasuryan B. Sanders B. Uma\u00f1a A. Zhang Y. Peng H. Duncan A. Wang Y. Li L. Verbridge S. and Slade D. 2020. Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration.\u00a0Science Signaling 13(641) p.eaba9157.  Casasanta M. Yoo C. Udayasuryan B. Sanders B. Uma\u00f1a A. Zhang Y. Peng H. Duncan A. Wang Y. Li L. Verbridge S. and Slade D. 2020. Fusobacterium nucleatum host-cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration.\u00a0Science Signaling 13(641) p.eaba9157.","DOI":"10.1126\/scisignal.aba9157"},{"key":"e_1_3_2_1_24_1","doi-asserted-by":"crossref","unstructured":"Abdulamir A. Hafidh R. and Bakar F. 2010. Molecular detection quantification and isolation of Streptococcus gallolyticus bacteria colonizing colorectal tumors: inflammation-driven potential of carcinogenesis via IL-1 COX-2 and IL-8.\u00a0Molecular Cancer 9(1) p.249.  Abdulamir A. Hafidh R. and Bakar F. 2010. Molecular detection quantification and isolation of Streptococcus gallolyticus bacteria colonizing colorectal tumors: inflammation-driven potential of carcinogenesis via IL-1 COX-2 and IL-8.\u00a0Molecular Cancer 9(1) p.249.","DOI":"10.1186\/1476-4598-9-249"},{"key":"e_1_3_2_1_25_1","doi-asserted-by":"crossref","unstructured":"Lu R. Wu S. Zhang Y. Xia Y. Liu X. Zheng Y. Chen H. Schaefer K. Zhou Z. Bissonnette M. Li L. and Sun J. 2014. Enteric bacterial protein AvrA promotes colonic tumorigenesis and activates colonic beta-catenin signaling pathway.\u00a0Oncogenesis 3(6) pp.e105-e105.  Lu R. Wu S. Zhang Y. Xia Y. Liu X. Zheng Y. Chen H. Schaefer K. Zhou Z. Bissonnette M. Li L. and Sun J. 2014. Enteric bacterial protein AvrA promotes colonic tumorigenesis and activates colonic beta-catenin signaling pathway.\u00a0Oncogenesis 3(6) pp.e105-e105.","DOI":"10.1038\/oncsis.2014.20"},{"key":"e_1_3_2_1_26_1","doi-asserted-by":"crossref","unstructured":"de Almeida C. Taddei A. and Amedei A. 2018. The controversial role of Enterococcus faecalis in colorectal cancer.\u00a0Therapeutic Advances in Gastroenterology 11 p.175628481878360.  de Almeida C. Taddei A. and Amedei A. 2018. The controversial role of Enterococcus faecalis in colorectal cancer.\u00a0Therapeutic Advances in Gastroenterology 11 p.175628481878360.","DOI":"10.1177\/1756284818783606"},{"key":"e_1_3_2_1_27_1","doi-asserted-by":"crossref","unstructured":"Evans M. Dizdaroglu M. and Cooke M. 2004. Oxidative DNA damage and disease: induction repair and significance.\u00a0Mutation Research\/Reviews in Mutation Research 567(1) pp.1-61.  Evans M. Dizdaroglu M. and Cooke M. 2004. Oxidative DNA damage and disease: induction repair and significance.\u00a0Mutation Research\/Reviews in Mutation Research 567(1) pp.1-61.","DOI":"10.1016\/j.mrrev.2003.11.001"},{"key":"e_1_3_2_1_28_1","doi-asserted-by":"crossref","unstructured":"Ho T. Chu E. Zhang X. Sheng J. Nakatsu D. Ng S. Chan A. Chan F. Sung J. and Yu J. 2017. Peptostreptococcus Anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice.\u00a0Gastroenterology 152(5) p.S1010.  Ho T. Chu E. Zhang X. Sheng J. Nakatsu D. Ng S. Chan A. Chan F. Sung J. and Yu J. 2017. Peptostreptococcus Anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice.\u00a0Gastroenterology 152(5) p.S1010.","DOI":"10.1016\/S0016-5085(17)33425-X"},{"key":"e_1_3_2_1_29_1","doi-asserted-by":"crossref","unstructured":"Cuevas-Ramos G. Petit C. Marcq I. Boury M. Oswald E. and Nougayrede J. 2010. Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells.\u00a0Proceedings of the National Academy of Sciences 107(25) pp.11537-11542.  Cuevas-Ramos G. Petit C. Marcq I. Boury M. Oswald E. and Nougayrede J. 2010. Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells.\u00a0Proceedings of the National Academy of Sciences 107(25) pp.11537-11542.","DOI":"10.1073\/pnas.1001261107"},{"key":"e_1_3_2_1_30_1","doi-asserted-by":"crossref","unstructured":"Cougnoux A. Dalmasso G. Martinez R. Buc E. Delmas J. Gibold L. Sauvanet P. Darcha C. D\u00e9chelotte P. Bonnet M. Pezet D. Wodrich H. Darfeuille-Michaud A. and Bonnet R. 2014. Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype.\u00a0Gut 63(12) pp.1932-1942.  Cougnoux A. Dalmasso G. Martinez R. Buc E. Delmas J. Gibold L. Sauvanet P. Darcha C. D\u00e9chelotte P. Bonnet M. Pezet D. Wodrich H. Darfeuille-Michaud A. and Bonnet R. 2014. Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype.\u00a0Gut 63(12) pp.1932-1942.","DOI":"10.1136\/gutjnl-2013-305257"},{"key":"e_1_3_2_1_31_1","doi-asserted-by":"crossref","unstructured":"Martin O. Bergonzini A. D'Amico F. Chen P. Shay J. Dupuy J. Svensson M. Masucci M. and Frisan T. 2019. Infection with genotoxin\u2010producing Salmonella enterica synergises with loss of the tumour suppressor APC in promoting genomic instability via the PI3K pathway in colonic epithelial cells.\u00a0Cellular Microbiology 21(12).  Martin O. Bergonzini A. D'Amico F. Chen P. Shay J. Dupuy J. Svensson M. Masucci M. and Frisan T. 2019. Infection with genotoxin\u2010producing Salmonella enterica synergises with loss of the tumour suppressor APC in promoting genomic instability via the PI3K pathway in colonic epithelial cells.\u00a0Cellular Microbiology 21(12).","DOI":"10.1111\/cmi.13099"},{"key":"e_1_3_2_1_32_1","first-page":"526","volume-title":"The risk of colorectal cancer in ulcerative colitis: a meta-analysis.\u00a0Gut, 48(4)","author":"Eaden J.","unstructured":"Eaden , J. , 2001. The risk of colorectal cancer in ulcerative colitis: a meta-analysis.\u00a0Gut, 48(4) , pp. 526 - 535 . Eaden, J., 2001. The risk of colorectal cancer in ulcerative colitis: a meta-analysis.\u00a0Gut, 48(4), pp.526-535."},{"key":"e_1_3_2_1_33_1","doi-asserted-by":"crossref","unstructured":"Canavan C. Abrams K. and Mayberry J. 2006. Meta-analysis: colorectal and small bowel cancer risk in patients with Crohn's disease.\u00a0Alimentary Pharmacology and Therapeutics 23(8) pp.1097-1104.  Canavan C. Abrams K. and Mayberry J. 2006. Meta-analysis: colorectal and small bowel cancer risk in patients with Crohn's disease.\u00a0Alimentary Pharmacology and Therapeutics 23(8) pp.1097-1104.","DOI":"10.1111\/j.1365-2036.2006.02854.x"},{"key":"e_1_3_2_1_34_1","doi-asserted-by":"crossref","unstructured":"Arthur J. Perez-Chanona E. M\u00fchlbauer M. Tomkovich S. Uronis J. Fan T. Campbell B. Abujamel T. Dogan B. Rogers A. Rhodes J. Stintzi A. Simpson K. Hansen J. Keku T. Fodor A. and Jobin C. 2012. Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota.\u00a0Science 338(6103) pp.120-123.  Arthur J. Perez-Chanona E. M\u00fchlbauer M. Tomkovich S. Uronis J. Fan T. Campbell B. Abujamel T. Dogan B. Rogers A. Rhodes J. Stintzi A. Simpson K. Hansen J. Keku T. Fodor A. and Jobin C. 2012. Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota.\u00a0Science 338(6103) pp.120-123.","DOI":"10.1126\/science.1224820"},{"key":"e_1_3_2_1_35_1","doi-asserted-by":"crossref","unstructured":"Lee T. Huang Y. Lu Y. Yeh Y. and Yu L. 2018. Hypoxia-induced intestinal barrier changes in balloon-assisted enteroscopy.\u00a0The Journal of Physiology 596(15) pp.3411-3424.  Lee T. Huang Y. Lu Y. Yeh Y. and Yu L. 2018. Hypoxia-induced intestinal barrier changes in balloon-assisted enteroscopy.\u00a0The Journal of Physiology 596(15) pp.3411-3424.","DOI":"10.1113\/JP275277"},{"key":"e_1_3_2_1_36_1","doi-asserted-by":"crossref","unstructured":"Kosa P. Szabo R. Molinolo A. and Bugge T. 2011. Suppression of Tumorigenicity-14 encoding matriptase is a critical suppressor of colitis and colitis-associated colon carcinogenesis.\u00a0Oncogene 31(32) pp.3679-3695.  Kosa P. Szabo R. Molinolo A. and Bugge T. 2011. Suppression of Tumorigenicity-14 encoding matriptase is a critical suppressor of colitis and colitis-associated colon carcinogenesis.\u00a0Oncogene 31(32) pp.3679-3695.","DOI":"10.1038\/onc.2011.545"},{"key":"e_1_3_2_1_37_1","doi-asserted-by":"crossref","unstructured":"Goodman B. and Gardner H. 2018. The microbiome and cancer.\u00a0The Journal of Pathology 244(5) pp.667-676.  Goodman B. and Gardner H. 2018. The microbiome and cancer.\u00a0The Journal of Pathology 244(5) pp.667-676.","DOI":"10.1002\/path.5047"},{"key":"e_1_3_2_1_38_1","doi-asserted-by":"crossref","unstructured":"Cremonesi E. Governa V. Garzon J. Mele V. Amicarella F. Muraro M. Trella E. Galati-Fournier V. Oertli D. D\u00e4ster S. Droeser R. Weixler B. Bolli M. Rosso R. Nitsche U. Khanna N. Egli A. Keck S. Slotta-Huspenina J. Terracciano L. Zajac P. Spagnoli G. Eppenberger-Castori S. Janssen K. Borsig L. and Iezzi G. 2018. Gut microbiota modulate T cell trafficking into human colorectal cancer.\u00a0Gut 67(11) pp.1984-1994.  Cremonesi E. Governa V. Garzon J. Mele V. Amicarella F. Muraro M. Trella E. Galati-Fournier V. Oertli D. D\u00e4ster S. Droeser R. Weixler B. Bolli M. Rosso R. Nitsche U. Khanna N. Egli A. Keck S. Slotta-Huspenina J. Terracciano L. Zajac P. Spagnoli G. Eppenberger-Castori S. Janssen K. Borsig L. and Iezzi G. 2018. Gut microbiota modulate T cell trafficking into human colorectal cancer.\u00a0Gut 67(11) pp.1984-1994.","DOI":"10.1136\/gutjnl-2016-313498"},{"key":"e_1_3_2_1_39_1","doi-asserted-by":"crossref","unstructured":"Kortylewski M. Xin H. Kujawski M. Lee H. Liu Y. Harris T. Drake C. Pardoll D. and Yu H. 2009. Regulation of the IL-23 and IL-12 Balance by Stat3 Signaling in the Tumor Microenvironment.\u00a0Cancer Cell 15(2) pp.114-123.  Kortylewski M. Xin H. Kujawski M. Lee H. Liu Y. Harris T. Drake C. Pardoll D. and Yu H. 2009. Regulation of the IL-23 and IL-12 Balance by Stat3 Signaling in the Tumor Microenvironment.\u00a0Cancer Cell 15(2) pp.114-123.","DOI":"10.1016\/j.ccr.2008.12.018"},{"key":"e_1_3_2_1_40_1","doi-asserted-by":"crossref","unstructured":"Wang K. Kim M. Di\u00a0Caro G. Wong J. Shalapour S. Wan J. Zhang W. Zhong Z. Sanchez-Lopez E. Wu L. Taniguchi K. Feng Y. Fearon E. Grivennikov S. and Karin M. 2014. Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis.\u00a0Immunity 41(6) pp.1052-1063.  Wang K. Kim M. Di\u00a0Caro G. Wong J. Shalapour S. Wan J. Zhang W. Zhong Z. Sanchez-Lopez E. Wu L. Taniguchi K. Feng Y. Fearon E. Grivennikov S. and Karin M. 2014. Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis.\u00a0Immunity 41(6) pp.1052-1063.","DOI":"10.1016\/j.immuni.2014.11.009"},{"key":"e_1_3_2_1_41_1","doi-asserted-by":"crossref","unstructured":"Song X. Gao H. Lin Y. Yao Y. Zhu S. Wang J. Liu Y. Yao X. Meng G. Shen N. Shi Y. Iwakura Y. and Qian Y. 2014. Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis.\u00a0Immunity 40(1) pp.140-152.  Song X. Gao H. Lin Y. Yao Y. Zhu S. Wang J. Liu Y. Yao X. Meng G. Shen N. Shi Y. Iwakura Y. and Qian Y. 2014. Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis.\u00a0Immunity 40(1) pp.140-152.","DOI":"10.1016\/j.immuni.2013.11.018"},{"key":"e_1_3_2_1_42_1","doi-asserted-by":"crossref","unstructured":"Wu S. Rhee K. Zhang M. Franco A. and Sears C. 2007. Bacteroides fragilis toxin stimulates intestinal epithelial cell shedding and \u03b3-secretase-dependent E-cadherin cleavage.\u00a0Journal of Cell Science 120(20) pp.3713-3713.  Wu S. Rhee K. Zhang M. Franco A. and Sears C. 2007. Bacteroides fragilis toxin stimulates intestinal epithelial cell shedding and \u03b3-secretase-dependent E-cadherin cleavage.\u00a0Journal of Cell Science 120(20) pp.3713-3713.","DOI":"10.1242\/jcs.03493"},{"key":"e_1_3_2_1_43_1","doi-asserted-by":"crossref","unstructured":"Deng Z. Mu J. Tseng M. Wattenberg B. Zhuang X. Egilmez N. Wang Q. Zhang L. Norris J. Guo H. Yan J. Haribabu B. Miller D. and Zhang H. 2015. Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.\u00a0Nature Communications 6(1).  Deng Z. Mu J. Tseng M. Wattenberg B. Zhuang X. Egilmez N. Wang Q. Zhang L. Norris J. Guo H. Yan J. Haribabu B. Miller D. and Zhang H. 2015. Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis.\u00a0Nature Communications 6(1).","DOI":"10.1038\/ncomms7956"},{"key":"e_1_3_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21551"},{"key":"e_1_3_2_1_45_1","doi-asserted-by":"crossref","unstructured":"Lee J. Liles E. Bent S. Levin T. and Corley D. 2014. Accuracy of Fecal Immunochemical Tests for Colorectal Cancer.\u00a0Annals of Internal Medicine 160(3) pp.171-181.  Lee J. Liles E. Bent S. Levin T. and Corley D. 2014. Accuracy of Fecal Immunochemical Tests for Colorectal Cancer.\u00a0Annals of Internal Medicine 160(3) pp.171-181.","DOI":"10.7326\/M13-1484"},{"key":"e_1_3_2_1_46_1","doi-asserted-by":"crossref","unstructured":"Guo S. Li L. Xu B. Li M. Zeng Q. Xiao H. Xue Y. Wu Y. Wang Y. Liu W. and Zhang G. 2018. A Simple and Novel Fecal Biomarker for Colorectal Cancer: Ratio of Fusobacterium Nucleatum to Probiotics Populations Based on Their Antagonistic Effect.\u00a0Clinical Chemistry 64(9) pp.1327-1337.  Guo S. Li L. Xu B. Li M. Zeng Q. Xiao H. Xue Y. Wu Y. Wang Y. Liu W. and Zhang G. 2018. A Simple and Novel Fecal Biomarker for Colorectal Cancer: Ratio of Fusobacterium Nucleatum to Probiotics Populations Based on Their Antagonistic Effect.\u00a0Clinical Chemistry 64(9) pp.1327-1337.","DOI":"10.1373\/clinchem.2018.289728"},{"key":"e_1_3_2_1_47_1","doi-asserted-by":"crossref","unstructured":"Mima K. Nishihara R. Qian Z. Cao Y. Sukawa Y. Nowak J. Yang J. Dou R. Masugi Y. Song M. Kostic A. Giannakis M. Bullman S. Milner D. Baba H. Giovannucci E. Garraway L. Freeman G. Dranoff G. Garrett W. Huttenhower C. Meyerson M. Meyerhardt J. Chan A. Fuchs C. and Ogino S. 2015. Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis.\u00a0Gut 65(12) pp.1973-1980.  Mima K. Nishihara R. Qian Z. Cao Y. Sukawa Y. Nowak J. Yang J. Dou R. Masugi Y. Song M. Kostic A. Giannakis M. Bullman S. Milner D. Baba H. Giovannucci E. Garraway L. Freeman G. Dranoff G. Garrett W. Huttenhower C. Meyerson M. Meyerhardt J. Chan A. Fuchs C. and Ogino S. 2015. Fusobacterium nucleatumin colorectal carcinoma tissue and patient prognosis.\u00a0Gut 65(12) pp.1973-1980.","DOI":"10.1136\/gutjnl-2015-310101"},{"key":"e_1_3_2_1_48_1","doi-asserted-by":"crossref","unstructured":"Cotillard A. Kennedy S. Kong L. Prifti E. Pons N. Le Chatelier E. Almeida M. Quinquis B. Levenez F. Galleron N. Gougis S. Rizkalla S. Batto J. Renault P. Dor\u00e9 J. Zucker J. Cl\u00e9ment K. Ehrlich S. Blotti\u00e8re H. Leclerc M. Juste C. de Wouters T. Lepage P. Fouqueray C. Basdevant A. Henegar C. Godard C. Fondacci M. Rohia A. Hajduch F. Weissenbach J. Pelletier E. Le Paslier D. Gauchi J. Gibrat J. Loux V. Carr\u00e9 W. Maguin E. van de Guchte M. Jamet A. Boumezbeur F. and Layec S. 2013. Dietary intervention impact on gut microbial gene richness.\u00a0Nature 500(7464) pp.585-588.  Cotillard A. Kennedy S. Kong L. Prifti E. Pons N. Le Chatelier E. Almeida M. Quinquis B. Levenez F. Galleron N. Gougis S. Rizkalla S. Batto J. Renault P. Dor\u00e9 J. Zucker J. Cl\u00e9ment K. Ehrlich S. Blotti\u00e8re H. Leclerc M. Juste C. de Wouters T. Lepage P. Fouqueray C. Basdevant A. Henegar C. Godard C. Fondacci M. Rohia A. Hajduch F. Weissenbach J. Pelletier E. Le Paslier D. Gauchi J. Gibrat J. Loux V. Carr\u00e9 W. Maguin E. van de Guchte M. Jamet A. Boumezbeur F. and Layec S. 2013. Dietary intervention impact on gut microbial gene richness.\u00a0Nature 500(7464) pp.585-588.","DOI":"10.1038\/nature12480"},{"key":"e_1_3_2_1_49_1","doi-asserted-by":"crossref","unstructured":"Yusof A. Isa Z. and Shah S. 2012. Dietary Patterns and Risk of Colorectal Cancer: A Systematic Review of Cohort Studies (2000-2011).\u00a0Asian Pacific Journal of Cancer Prevention 13(9) pp.4713-4717.  Yusof A. Isa Z. and Shah S. 2012. Dietary Patterns and Risk of Colorectal Cancer: A Systematic Review of Cohort Studies (2000-2011).\u00a0Asian Pacific Journal of Cancer Prevention 13(9) pp.4713-4717.","DOI":"10.7314\/APJCP.2012.13.9.4713"},{"key":"e_1_3_2_1_50_1","doi-asserted-by":"crossref","unstructured":"Fong W. Li Q. and Yu J. 2020. Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer.\u00a0Oncogene 39(26) pp.4925-4943.  Fong W. Li Q. and Yu J. 2020. Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer.\u00a0Oncogene 39(26) pp.4925-4943.","DOI":"10.1038\/s41388-020-1341-1"},{"key":"e_1_3_2_1_51_1","doi-asserted-by":"crossref","unstructured":"Quraishi M. Widlak M. Bhala N. Moore D. Price M. Sharma N. and Iqbal T. 2017. Systematic review with meta-analysis: the efficacy of faecal microbiota transplantation for the treatment of recurrent and refractory Clostridium difficile infection.\u00a0Alimentary Pharmacology & Therapeutics 46(5) pp.479-493.  Quraishi M. Widlak M. Bhala N. Moore D. Price M. Sharma N. and Iqbal T. 2017. Systematic review with meta-analysis: the efficacy of faecal microbiota transplantation for the treatment of recurrent and refractory Clostridium difficile infection.\u00a0Alimentary Pharmacology & Therapeutics 46(5) pp.479-493.","DOI":"10.1111\/apt.14201"},{"key":"e_1_3_2_1_52_1","doi-asserted-by":"crossref","unstructured":"Rosshart S. Vassallo B. Angeletti D. Hutchinson D. Morgan A. Takeda K. Hickman H. McCulloch J. Badger J. Ajami N. Trinchieri G. Pardo-Manuel de Villena F. Yewdell J. and Rehermann B. 2017. Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance.\u00a0Cell 171(5) pp.1015-1028.e13.  Rosshart S. Vassallo B. Angeletti D. Hutchinson D. Morgan A. Takeda K. Hickman H. McCulloch J. Badger J. Ajami N. Trinchieri G. Pardo-Manuel de Villena F. Yewdell J. and Rehermann B. 2017. Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance.\u00a0Cell 171(5) pp.1015-1028.e13.","DOI":"10.1016\/j.cell.2017.09.016"}],"event":{"name":"ICBBS 2021: 2021 10th International Conference on Bioinformatics and Biomedical Science","acronym":"ICBBS 2021","location":"Xiamen China"},"container-title":["2021 10th International Conference on Bioinformatics and Biomedical Science"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3498731.3498757","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/3498731.3498757","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T20:49:07Z","timestamp":1750193347000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3498731.3498757"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,29]]},"references-count":52,"alternative-id":["10.1145\/3498731.3498757","10.1145\/3498731"],"URL":"https:\/\/doi.org\/10.1145\/3498731.3498757","relation":{},"subject":[],"published":{"date-parts":[[2021,10,29]]},"assertion":[{"value":"2022-01-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}