{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T01:26:18Z","timestamp":1755998778297,"version":"3.41.0"},"publisher-location":"New York, NY, USA","reference-count":11,"publisher":"ACM","license":[{"start":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T00:00:00Z","timestamp":1650412800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4,20]]},"DOI":"10.1145\/3535694.3535696","type":"proceedings-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T16:52:58Z","timestamp":1657558378000},"page":"5-8","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["In silico investigation of oxindole alkaloids from Uncaria perrottetii and Uncaria lanosa f. philippinensis for COVID-19 therapy: binding site prediction and molecular docking"],"prefix":"10.1145","author":[{"given":"Akira Kio Valdorea","family":"Kikuchi","sequence":"first","affiliation":[{"name":"School of Chemical, Biological, and Materials Engineering and Sciences, Mapua University, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shealtiel William Sta. Maria","family":"Chan","sequence":"additional","affiliation":[{"name":"School of Chemical, Biological, and Materials Engineering and Sciences, Mapua University, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan Christian","family":"Mailem","sequence":"additional","affiliation":[{"name":"School of Chemical, Biological, and Materials Engineering and Sciences, Mapua University, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marineil Carillo","family":"Gomez","sequence":"additional","affiliation":[{"name":"School of Chemical, Biological, and Materials Engineering and Sciences, Mapua University, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lemmuel Lara","family":"Tayo","sequence":"additional","affiliation":[{"name":"School of Chemical, Biological, and Materials Engineering and Sciences, Mapua University, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"320","published-online":{"date-parts":[[2022,7,11]]},"reference":[{"key":"e_1_3_2_1_1_1","unstructured":"World Health Organization WHO Coronavirus (COVID-19) Dashboard | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data  World Health Organization WHO Coronavirus (COVID-19) Dashboard | WHO Coronavirus (COVID-19) Dashboard With Vaccination Data"},{"volume-title":"Al Khodor S 2020 Pathophysiology and treatment strategies for COVID-19 J. Transl. Med. 18 1\u20139","author":"Kumar M","key":"e_1_3_2_1_2_1","unstructured":"Kumar M and Al Khodor S 2020 Pathophysiology and treatment strategies for COVID-19 J. Transl. Med. 18 1\u20139 Kumar M and Al Khodor S 2020 Pathophysiology and treatment strategies for COVID-19 J. Transl. Med. 18 1\u20139"},{"volume-title":"Remdesivir has little or no impact on survival","author":"Dyer 0","key":"e_1_3_2_1_3_1","unstructured":"Dyer O 202 0 Covid -19 : Remdesivir has little or no impact on survival , WHO trial shows BMJ 371 m4057 Dyer O 2020 Covid-19: Remdesivir has little or no impact on survival, WHO trial shows BMJ 371 m4057"},{"key":"e_1_3_2_1_4_1","unstructured":"consortium W S trial Pan H Peto R Karim Q A Alejandria M Henao-Restrepo A M Garc\u00eda C H Kieny M-P Malekzadeh R Murthy S Preziosi M-P Reddy S Periago M R Sathiyamoorthy V R\u00f8ttingen J-A Swaminathan S and as the members of the Writing Committee assume responsibility for the content and integrity of this article 2020 Repurposed antiviral drugs for COVID-19 \u2013interim WHO SOLIDARITY trial results medRxiv 2020.10.15.20209817  consortium W S trial Pan H Peto R Karim Q A Alejandria M Henao-Restrepo A M Garc\u00eda C H Kieny M-P Malekzadeh R Murthy S Preziosi M-P Reddy S Periago M R Sathiyamoorthy V R\u00f8ttingen J-A Swaminathan S and as the members of the Writing Committee assume responsibility for the content and integrity of this article 2020 Repurposed antiviral drugs for COVID-19 \u2013interim WHO SOLIDARITY trial results medRxiv 2020.10.15.20209817"},{"key":"e_1_3_2_1_5_1","unstructured":"Roy A 2017 A review on the alkaloids an important therapeutic compound from plants Int. J. Plant Biotechnol.  Roy A 2017 A review on the alkaloids an important therapeutic compound from plants Int. J. Plant Biotechnol."},{"key":"e_1_3_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-63473-3.00012-5"},{"key":"e_1_3_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jksus.2017.12.008"},{"key":"e_1_3_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/wcms.1397"},{"key":"e_1_3_2_1_9_1","doi-asserted-by":"crossref","unstructured":"Elzupir A O 2020 Caffeine and caffeine-containing pharmaceuticals as promising inhibitors for 3-chymotrypsin-like protease of SARS-CoV-2 J. Biomol. Struct. Dyn. 1  Elzupir A O 2020 Caffeine and caffeine-containing pharmaceuticals as promising inhibitors for 3-chymotrypsin-like protease of SARS-CoV-2 J. Biomol. Struct. Dyn. 1","DOI":"10.1080\/07391102.2020.1835732"},{"key":"e_1_3_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/ci5006004"},{"key":"e_1_3_2_1_11_1","doi-asserted-by":"crossref","unstructured":"AC W RA L and JM T 1995 LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions Protein Eng. 8 127\u201334  AC W RA L and JM T 1995 LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions Protein Eng. 8 127\u201334","DOI":"10.1093\/protein\/8.2.127"}],"event":{"name":"ICBET 2022: 2022 12th International Conference on Biomedical Engineering and Technology","acronym":"ICBET 2022","location":"Tokyo Japan"},"container-title":["Proceedings of the 12th International Conference on Biomedical Engineering and Technology"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3535694.3535696","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/3535694.3535696","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T19:30:53Z","timestamp":1750188653000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3535694.3535696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,20]]},"references-count":11,"alternative-id":["10.1145\/3535694.3535696","10.1145\/3535694"],"URL":"https:\/\/doi.org\/10.1145\/3535694.3535696","relation":{},"subject":[],"published":{"date-parts":[[2022,4,20]]},"assertion":[{"value":"2022-07-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}