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The unintentional coupling of qubits to their environment and each other adds significant noise to computation, and improved methods to combat decoherence are required to boost the performance of quantum algorithms on real machines. While many existing techniques for mitigating error rely on adding extra gates to the circuit\u00a0[\n            <jats:xref ref-type=\"bibr\">13<\/jats:xref>\n            ,\n            <jats:xref ref-type=\"bibr\">20<\/jats:xref>\n            ,\n            <jats:xref ref-type=\"bibr\">56<\/jats:xref>\n            ], calibrating new gates\u00a0[\n            <jats:xref ref-type=\"bibr\">50<\/jats:xref>\n            ], or extending a circuit\u2019s runtime\u00a0[\n            <jats:xref ref-type=\"bibr\">32<\/jats:xref>\n            ], this article\u2019s primary contribution leverages the gates already present in a quantum program without extending circuit duration. We exploit circuit slack for single-qubit gates that occur in idle windows, scheduling the gates such that their timing can counteract some errors.\n          <\/jats:p>\n          <jats:p>\n            Spin-echo corrections that mitigate decoherence on idling qubits act as inspiration for this work. Theoretical models, however, fail to capture all sources of noise in Noisy Intermediate Scale Quantum devices, making practical solutions necessary that better minimize the impact of unpredictable errors in quantum machines. This article presents TimeStitch: a novel framework that pinpoints the optimum execution schedules for single-qubit gates within quantum circuits. TimeStitch, implemented as a compilation pass, leverages the reversible nature of quantum computation to boost the success of circuits on real quantum machines. Unlike past approaches that apply reversibility properties to improve quantum circuit execution\u00a0[\n            <jats:xref ref-type=\"bibr\">35<\/jats:xref>\n            ], TimeStitch amplifies fidelity without violating critical path frontiers in either the slack tuning procedures or the final rescheduled circuit. On average, compared to a state-of-the-art baseline, a practically constrained TimeStitch achieves a mean 38% relative improvement in success rates, with a maximum of 106%, while observing bounds on circuit depth. When unconstrained by depth criteria, TimeStitch produces a mean relative fidelity increase of 50% with a maximum of 256%. Finally, when TimeStitch intelligently leverages periodic dynamical decoupling within its scheduling framework, a mean 64% improvement is observed over the baseline, relatively outperforming stand-alone dynamical decoupling by 19%, with a maximum of 287%.\n          <\/jats:p>","DOI":"10.1145\/3548778","type":"journal-article","created":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T09:30:03Z","timestamp":1658568603000},"page":"1-27","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["TimeStitch: Exploiting Slack to Mitigate Decoherence in Quantum Circuits"],"prefix":"10.1145","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1169-3696","authenticated-orcid":false,"given":"Kaitlin N.","family":"Smith","sequence":"first","affiliation":[{"name":"University of Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2334-2682","authenticated-orcid":false,"given":"Gokul Subramanian","family":"Ravi","sequence":"additional","affiliation":[{"name":"University of Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3378-8589","authenticated-orcid":false,"given":"Prakash","family":"Murali","sequence":"additional","affiliation":[{"name":"Princeton University, Princeton, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0775-8274","authenticated-orcid":false,"given":"Jonathan M.","family":"Baker","sequence":"additional","affiliation":[{"name":"University of Chicago, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1441-9067","authenticated-orcid":false,"given":"Nathan","family":"Earnest","sequence":"additional","affiliation":[{"name":"IBM Quantum, IBM T. 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