{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T07:10:01Z","timestamp":1755846601951,"version":"3.44.0"},"publisher-location":"New York, NY, USA","reference-count":12,"publisher":"ACM","license":[{"start":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T00:00:00Z","timestamp":1665619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10,13]]},"DOI":"10.1145\/3570773.3570831","type":"proceedings-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T15:57:42Z","timestamp":1670601462000},"page":"118-122","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Astragaloside IV May Bind to CD25 Gene to Repress HBV Induced Regulatory T Cell Expression"],"prefix":"10.1145","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4327-0118","authenticated-orcid":false,"given":"Krystal Kairui","family":"Wang","sequence":"first","affiliation":[{"name":"Northfield Mount Hermon, United States"}]}],"member":"320","published-online":{"date-parts":[[2022,12,9]]},"reference":[{"key":"e_1_3_2_1_1_1","doi-asserted-by":"publisher","unstructured":"Stoop J. N. van der Molen R. G. Baan C. C. van der Laan L. J. Kuipers E. J. Kusters J. G. & Janssen H. L. 2005. Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection. Hepatology (Baltimore Md.) 41 (4) 771\u2013778. https:\/\/doi.org\/10.1002\/hep.20649","DOI":"10.1002\/hep.20649"},{"key":"e_1_3_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.patbio.2009.11.001"},{"key":"e_1_3_2_1_3_1","unstructured":"Tang B. Z. Li M. & Gao Y. Q. 2010. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 30(8) 823\u2013827."},{"key":"e_1_3_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2013.01.038"},{"key":"e_1_3_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-015-1729-x"},{"key":"e_1_3_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24224064"},{"key":"e_1_3_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-014-1744-x"},{"key":"e_1_3_2_1_8_1","volume-title":"Vio\u00ae Dyes meet REAfinity\u2122 Antibodies \u2013 antibody-fluorochrome conjugates for high-resolution multiparameter flow cytometry analysis [poster abstract]. Miltenyi Biotec GmbH","author":"Evaristo C.","year":"2017","unstructured":"Evaristo, C., Vahldieck, M., Krauthaeuser, S., Jansen, N., Wilske, N., Richter, A., & Dose, C. 2017. Vio\u00ae Dyes meet REAfinity\u2122 Antibodies \u2013 antibody-fluorochrome conjugates for high-resolution multiparameter flow cytometry analysis [poster abstract]. Miltenyi Biotec GmbH, Bergisch Gladbach, Germany. https:\/\/www.miltenyibiotec.com\/_Resources\/Persistent\/bf0b810a051b7bd6c9a019b1502ebcc1c125d53f\/Human%20Treg%20antibody%20panel.pdf"},{"key":"e_1_3_2_1_9_1","doi-asserted-by":"publisher","unstructured":"Srivastava S. Somasagara R. R. Hegde M. Nishana M. Tadi S. K. Srivastava M. Choudhary B. & Raghavan S. C. 2016. Quercetin a Natural Flavonoid Interacts with DNA Arrests Cell Cycle and Causes Tumor Regression by Activating Mitochondrial Pathway of Apoptosis. Scientific Reports 6(1). https:\/\/doi.org\/10.1038\/srep24049","DOI":"10.1038\/srep24049"},{"key":"e_1_3_2_1_10_1","doi-asserted-by":"publisher","unstructured":"Wang L. Chi Y. F. Yuan Z. T. Zhou W. C. Yin P. H. Zhang X. M. Peng W. & Cai H. 2014. Astragaloside IV inhibits renal tubulointerstitial fibrosis by blocking TGF-\u03b2\/Smad signaling pathway in vivo and in vitro. Experimental biology and medicine (Maywood N.J.) 239 (10) 1310\u20131324. https:\/\/doi.org\/10.1177\/1535370214532597","DOI":"10.1177\/1535370214532597"},{"key":"e_1_3_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2019.112319"},{"key":"e_1_3_2_1_12_1","doi-asserted-by":"publisher","unstructured":"Mercer F. & Unutmaz D. 2009. The biology of FoxP3: a key player in immune suppression during infections autoimmune diseases and cancer. Advances in experimental medicine and biology 665 47\u201359. https:\/\/doi.org\/10.1007\/978-1-4419-1599-3_4","DOI":"10.1007\/978-1-4419-1599-3_4"}],"event":{"name":"ISAIMS 2022: 2022 3rd International Symposium on Artificial Intelligence for Medicine Sciences","acronym":"ISAIMS 2022","location":"Amsterdam Netherlands"},"container-title":["Proceedings of the 3rd International Symposium on Artificial Intelligence for Medicine Sciences"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3570773.3570831","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/3570773.3570831","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T06:50:15Z","timestamp":1755845415000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3570773.3570831"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,13]]},"references-count":12,"alternative-id":["10.1145\/3570773.3570831","10.1145\/3570773"],"URL":"https:\/\/doi.org\/10.1145\/3570773.3570831","relation":{},"subject":[],"published":{"date-parts":[[2022,10,13]]},"assertion":[{"value":"2022-12-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}