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The recent emergence of blockchain with IoT provides significant growth in the healthcare industry to improve security, privacy, efficiency, and transparency with more business opportunities. Nevertheless, conventional healthcare schemes suffer from various security attacks like collusion, phishing, masquerade, etc. Therefore, a privacy-preserving<jats:bold>Distributed Application (DA)<\/jats:bold>is proposed in this paper using blockchain technology to create and maintain healthcare certificates. Here, the distributed application provides an interface between the blockchain network and system objects like healthcare centers, verifiers, and regular authorities to generate and issue medical documents. In addition, it also ensures security by specifying rules using various smart contracts. To evaluate the performance of the proposed scheme, various experimental tests are conducted using the Etherscan tool for measuring operation cost, latency, and processing time. Here, the efficiency of the proposed system is also compared to the existing systems in terms of latency, throughput, and response time. The experimental results and comparative analysis show that the proposed work is more efficient than the existing techniques.<\/jats:p>","DOI":"10.1145\/3577926","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T14:05:37Z","timestamp":1671717937000},"page":"1-17","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":108,"title":["Blockchain-Based Privacy Preservation for IoT-Enabled Healthcare System"],"prefix":"10.1145","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1990-1533","authenticated-orcid":false,"given":"Pratima","family":"Sharma","sequence":"first","affiliation":[{"name":"Bennett University, India"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0191-0175","authenticated-orcid":false,"given":"Suyel","family":"Namasudra","sequence":"additional","affiliation":[{"name":"National Institute of Technology Agartala, Tripura, India"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5396-8897","authenticated-orcid":false,"given":"Naveen","family":"Chilamkurti","sequence":"additional","affiliation":[{"name":"La Trobe University, Australia"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6555-3464","authenticated-orcid":false,"given":"Byung-Gyu","family":"Kim","sequence":"additional","affiliation":[{"name":"Sookmyung Women's University, Republic of Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5541-6319","authenticated-orcid":false,"given":"Ruben","family":"Gonzalez Crespo","sequence":"additional","affiliation":[{"name":"Universidad International de La Rioja, Spain"}]}],"member":"320","published-online":{"date-parts":[[2023,3,2]]},"reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.23919\/ICACT.2019.8702049"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1109\/ICDCS.2011.83"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1109\/ACCESS.2019.2952942"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1145\/3392665"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1109\/GLOBECOM42002.2020.9322472"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11831-020-09426-0"},{"key":"e_1_3_1_8_2","unstructured":"S. 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