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Our findings describe experiences of co-creating knowledge around digitization of SMEs on a regional level, beyond individual company contexts. We reflect on the benefits and challenges such an approach affords and highlight the importance of interpersonal relationships and similarities between practices in different contexts to enable intended but also initially unexpected knowledge spillovers. Our findings highlight how a praxeological approach to CSCW can be influential in regional development programs, and open this field to CSCW research and design. 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