{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T14:21:51Z","timestamp":1765808511192,"version":"3.44.0"},"publisher-location":"New York, NY, USA","reference-count":2,"publisher":"ACM","license":[{"start":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T00:00:00Z","timestamp":1732233600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.acm.org\/publications\/policies\/copyright_policy#Background"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11,22]]},"DOI":"10.1145\/3698587.3701425","type":"proceedings-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T10:05:08Z","timestamp":1734343508000},"page":"1-1","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["MLPA: A Multi-scale Digital Twin Framework for Personalized Cancer Simulation and Treatment Optimization"],"prefix":"10.1145","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-9293-6849","authenticated-orcid":false,"given":"James","family":"Gu","sequence":"first","affiliation":[{"name":"Basis Independent Fremont, Fremont, California, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8829-7504","authenticated-orcid":false,"given":"Jake Y.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics and Data Science, Systems Pharmacology AI Research Center the University of Alabama at Birmingham, Birmingham, Alabama, US"}]}],"member":"320","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"e_1_3_2_1_1_1","doi-asserted-by":"crossref","unstructured":"C. A. Valentim J. A. Rabi S. A. David 2023. Cellular-automaton model for tumor growth dynamics: Virtualization of different scenarios. Computers in Biology and Medicine 153","DOI":"10.1016\/j.compbiomed.2022.106481"},{"key":"e_1_3_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1218838110"}],"event":{"name":"BCB '24: 15th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics","sponsor":["SIGBio ACM Special Interest Group on Bioinformatics"],"location":"Shenzhen China","acronym":"BCB '24"},"container-title":["Proceedings of the 15th ACM International Conference on Bioinformatics, Computational Biology and Health Informatics"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3698587.3701425","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/3698587.3701425","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T11:25:17Z","timestamp":1755861917000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3698587.3701425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,22]]},"references-count":2,"alternative-id":["10.1145\/3698587.3701425","10.1145\/3698587"],"URL":"https:\/\/doi.org\/10.1145\/3698587.3701425","relation":{},"subject":[],"published":{"date-parts":[[2024,11,22]]},"assertion":[{"value":"2024-12-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}