{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T10:50:20Z","timestamp":1773312620509,"version":"3.50.1"},"publisher-location":"New York, NY, USA","reference-count":21,"publisher":"ACM","license":[{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11,8]]},"DOI":"10.1145\/3707127.3707168","type":"proceedings-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T12:34:06Z","timestamp":1738845246000},"page":"248-252","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Communication Analysis between Human Hair-Follicles and Immune Cells with Single-cell RNA-seq"],"prefix":"10.1145","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2282-4382","authenticated-orcid":false,"given":"Ayaka","family":"Mori-Ichioka","sequence":"first","affiliation":[{"name":"Graduate School of Information Science and Technology, Osaka Univesity, Suita, Japan"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2035-3232","authenticated-orcid":false,"given":"Hironori","family":"Shigeta","sequence":"additional","affiliation":[{"name":"Graduate School of Information Science and Technology, Osaka Univesity, Suita, Japan"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3861-6444","authenticated-orcid":false,"given":"Shigeto","family":"Seno","sequence":"additional","affiliation":[{"name":"Graduate School of Information Science and Technology, Osaka Univesity, Suita, Japan"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4701-3779","authenticated-orcid":false,"given":"Hideo","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Graduate School of Information Science and Technology, Osaka Univesity, Suita, Japan"}]}],"member":"320","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"e_1_3_3_1_2_2","doi-asserted-by":"crossref","unstructured":"Dvir Aran Agnieszka\u00a0P Looney Leqian Liu Esther Wu Valerie Fong Austin Hsu Suzanna Chak Ram\u00a0P Naikawadi Paul\u00a0J Wolters Adam\u00a0R Abate et\u00a0al. 2019. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. Nature Immunology 20 2 (2019) 163\u2013172.","DOI":"10.1038\/s41590-018-0276-y"},{"key":"e_1_3_3_1_3_2","doi-asserted-by":"crossref","unstructured":"Eddie Cano-Gamez Blagoje Soskic Theodoros\u00a0I Roumeliotis Ernest So Deborah\u00a0J Smyth Marta Baldrighi David Will\u00e9 Nikolina Nakic Jorge Esparza-Gordillo Christopher\u00a0GC Larminie et\u00a0al. 2020. Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines. Nature Communications 11 1 (2020) 1801.","DOI":"10.1038\/s41467-020-15543-y"},{"key":"e_1_3_3_1_4_2","doi-asserted-by":"crossref","unstructured":"Bu\u00a0Young Choi. 2018. Hair-growth potential of ginseng and its major metabolites: a review on its molecular mechanisms. International Journal of Molecular Sciences 19 9 (2018) 2703.","DOI":"10.3390\/ijms19092703"},{"key":"e_1_3_3_1_5_2","doi-asserted-by":"crossref","unstructured":"Dante Dahabreh Seungyeon Jung Yael Renert-Yuval Jonathan Bar Ester Del\u00a0Duca and Emma Guttman-Yassky. 2023. Alopecia areata: current treatments and new directions. American Journal of Clinical Dermatology 24 6 (2023) 895\u2013912.","DOI":"10.1007\/s40257-023-00808-1"},{"key":"e_1_3_3_1_6_2","doi-asserted-by":"crossref","unstructured":"Daniel Dimitrov D\u00e9nes T\u00fcrei Martin Garrido-Rodriguez Paul\u00a0L Burmedi James\u00a0S Nagai Charlotte Boys Ricardo\u00a0O Ramirez\u00a0Flores Hyojin Kim Bence Szalai Ivan\u00a0G Costa et\u00a0al. 2022. Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data. Nature Communications 13 1 (2022) 3224.","DOI":"10.1038\/s41467-022-30755-0"},{"key":"e_1_3_3_1_7_2","doi-asserted-by":"crossref","unstructured":"Ryan\u00a0R Driskell Carlos Clavel Michael Rendl and Fiona\u00a0M Watt. 2011. Hair follicle dermal papilla cells at a glance. Journal of cell science 124 8 (2011) 1179\u20131182.","DOI":"10.1242\/jcs.082446"},{"key":"e_1_3_3_1_8_2","doi-asserted-by":"crossref","unstructured":"Yuxue Gao Qingguo Xu Xinqiang Li Yuan Guo Bowen Zhang Yan Jin Cunle Zhu Yuntai Shen Pengxiang Yang Ying Shi et\u00a0al. 2022. Heterogeneity induced GZMA-F2R communication inefficient impairs antitumor immunotherapy of PD-1 mAb through JAK2\/STAT1 signal suppression in hepatocellular carcinoma. Cell Death & Disease 13 3 (2022) 213.","DOI":"10.1038\/s41419-022-04654-7"},{"key":"e_1_3_3_1_9_2","doi-asserted-by":"crossref","unstructured":"Yuhan Hao Stephanie Hao Erica Andersen-Nissen William\u00a0M Mauck Shiwei Zheng Andrew Butler Maddie\u00a0J Lee Aaron\u00a0J Wilk Charlotte Darby Michael Zager et\u00a0al. 2021. Integrated analysis of multimodal single-cell data. Cell 184 13 (2021) 3573\u20133587.","DOI":"10.1016\/j.cell.2021.04.048"},{"key":"e_1_3_3_1_10_2","doi-asserted-by":"crossref","unstructured":"Taisuke Ito and Yoshiki Tokura. 2014. The role of cytokines and chemokines in the T-cell-mediated autoimmune process in alopecia areata. Experimental dermatology 23 11 (2014) 787\u2013791.","DOI":"10.1111\/exd.12489"},{"key":"e_1_3_3_1_11_2","doi-asserted-by":"crossref","unstructured":"Ilya Korsunsky Nghia Millard Jean Fan Kamil Slowikowski Fan Zhang Kevin Wei Yuriy Baglaenko Michael Brenner Po-ru Loh and Soumya Raychaudhuri. 2019. Fast sensitive and accurate integration of single-cell data with Harmony. Nature Methods 16 12 (2019) 1289\u20131296.","DOI":"10.1038\/s41592-019-0619-0"},{"key":"e_1_3_3_1_12_2","doi-asserted-by":"crossref","unstructured":"Eunice\u00a0Y Lee Zhenpeng Dai Abhinav Jaiswal Eddy Hsi\u00a0Chun Wang Niroshana Anandasabapathy and Angela\u00a0M Christiano. 2023. Functional interrogation of lymphocyte subsets in alopecia areata using single-cell RNA sequencing. Proceedings of the National Academy of Sciences 120 29 (2023) e2305764120.","DOI":"10.1073\/pnas.2305764120"},{"key":"e_1_3_3_1_13_2","doi-asserted-by":"crossref","unstructured":"Neil\u00a0A Mabbott J\u00a0Kenneth Baillie Helen Brown Tom\u00a0C Freeman and David\u00a0A Hume. 2013. An expression atlas of human primary cells: inference of gene function from coexpression networks. BMC Genomics 14 (2013) 1\u201313.","DOI":"10.1186\/1471-2164-14-632"},{"key":"e_1_3_3_1_14_2","doi-asserted-by":"crossref","unstructured":"Kevin\u00a0J McElwee Amos Gilhar Desmond\u00a0J Tobin Yuval Ramot John\u00a0P Sundberg Michiko Nakamura Marta Bertolini Shigeki Inui Yoshiki Tokura LE King et\u00a0al. 2013. What causes alopecia areata? Section Editors: Ralf Paus Manchester\/L\u00fcbeck and Raymond Cho San Francisco. Experimental dermatology 22 9 (2013) 609\u2013626.","DOI":"10.1111\/exd.12209"},{"key":"e_1_3_3_1_15_2","doi-asserted-by":"crossref","unstructured":"Akihiro Nomura and Hideo Matsuda. 2022. Inference of Cell-Cell Communication for Detecting Immune Disease-Associated Signaling Pathways using Single-Cell RNA-seq. Proceedings of the 2022 9th International Conference on Biomedical and Bioinformatics Engineering (2022) 74\u201380.","DOI":"10.1145\/3574198.3574210"},{"key":"e_1_3_3_1_16_2","doi-asserted-by":"crossref","unstructured":"Benjamin Ober-Reynolds Chen Wang Justin\u00a0M Ko Eon\u00a0J Rios Sumaira\u00a0Z Aasi Mark\u00a0M Davis Anthony\u00a0E Oro and William\u00a0J Greenleaf. 2023. Integrated single-cell chromatin and transcriptomic analyses of human scalp identify gene-regulatory programs and critical cell types for hair and skin diseases. Nature Genetics 55 8 (2023) 1288\u20131300.","DOI":"10.1038\/s41588-023-01445-4"},{"key":"e_1_3_3_1_17_2","doi-asserted-by":"crossref","unstructured":"Marlon\u00a0R Schneider Ruth Schmidt-Ullrich and Ralf Paus. 2009. The hair follicle as a dynamic miniorgan. Current Biology 19 3 (2009) R132\u2013R142.","DOI":"10.1016\/j.cub.2008.12.005"},{"key":"e_1_3_3_1_18_2","doi-asserted-by":"crossref","unstructured":"Kelly Street Davide Risso Russell\u00a0B Fletcher Diya Das John Ngai Nir Yosef Elizabeth Purdom and Sandrine Dudoit. 2018. Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics. BMC Genomics 19 (2018) 1\u201316.","DOI":"10.1186\/s12864-018-4772-0"},{"key":"e_1_3_3_1_19_2","doi-asserted-by":"crossref","unstructured":"Yuan Tian Mariana Babor Jerome Lane Veronique Schulten Veena\u00a0S Patil Gr\u00e9gory Seumois Sandy\u00a0L Rosales Zheng Fu Gaelle Picarda Julie Burel et\u00a0al. 2017. Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA. Nature Communications 8 1 (2017) 1473.","DOI":"10.1038\/s41467-017-01728-5"},{"key":"e_1_3_3_1_20_2","doi-asserted-by":"crossref","unstructured":"Koen Van\u00a0den Berge Hector Roux\u00a0de B\u00e9zieux Kelly Street Wouter Saelens Robrecht Cannoodt Yvan Saeys Sandrine Dudoit and Lieven Clement. 2020. Trajectory-based differential expression analysis for single-cell sequencing data. Nature Communications 11 1 (2020) 1201.","DOI":"10.1038\/s41467-020-14766-3"},{"key":"e_1_3_3_1_21_2","doi-asserted-by":"crossref","unstructured":"Minjuan Wu Chen Xu Junfeng Jiang Sha Xu Jun Xiong Xiaoming Fan Kaihong Ji Yunpeng Zhao Haitao Ni Yue Wang et\u00a0al. 2022. JAM-A facilitates hair follicle regeneration in alopecia areata through functioning as ceRNA to protect VCAN expression in dermal papilla cells. Precision Clinical Medicine 5 3 (2022) pbac020.","DOI":"10.1093\/pcmedi\/pbac020"},{"key":"e_1_3_3_1_22_2","doi-asserted-by":"crossref","unstructured":"Cheng Zhou Xiangqian Li Chen Wang and Jianzhong Zhang. 2021. Alopecia areata: an update on etiopathogenesis diagnosis and management. Clinical Reviews in Allergy & Immunology 61 3 (2021) 403\u2013423.","DOI":"10.1007\/s12016-021-08883-0"}],"event":{"name":"ICBBE 2024: 2024 11th International Conference on Biomedical and Bioinformatics Engineering","location":"Osaka Japan","acronym":"ICBBE 2024"},"container-title":["Proceedings of the 2024 11th International Conference on Biomedical and Bioinformatics Engineering"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3707127.3707168","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/3707127.3707168","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T01:18:14Z","timestamp":1750295894000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3707127.3707168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,8]]},"references-count":21,"alternative-id":["10.1145\/3707127.3707168","10.1145\/3707127"],"URL":"https:\/\/doi.org\/10.1145\/3707127.3707168","relation":{},"subject":[],"published":{"date-parts":[[2024,11,8]]},"assertion":[{"value":"2025-02-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}