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Data"],"published-print":{"date-parts":[[2026,1,31]]},"abstract":"<jats:p>Federated learning is a promising bridge that connects machine learning methods and multi-central medical data. It trains models using the local data, and protects the privacy of data. There are many methods for federated learning to aggregate models, especially personalized methods, which show relatively excellent performance. However, most of them excessively pay attention to global and local information while ignoring the random components during aggregating. That limits their performance in metrics like accuracy, specificity, and sensitivity. We propose a method (denoted by FedDiv) to make a balance between these metrics. The basic idea is to extract centralized features meanwhile filtering random components, and conduct personalized aggregation. These centralized features draw encoders\u2019 attention, which enhances the performance of personalized models in specificity and sensitivity. Besides, they contain more global and local information, which is advantageous for personalized aggregation. Meanwhile, our personalized method preserves the local information as far as possible during aggregating models. These local information are the critical factor for the personalized models to perform better in accuracy. Finally, we validate this method in three public and one private medical datasets. Comparing with 14 federated methods, our method achieves the best performance in metrics including accuracy, specificity, sensitivity, and F1 score.<\/jats:p>","DOI":"10.1145\/3737649","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T10:36:01Z","timestamp":1748428561000},"page":"1-31","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Medical Federated Learning with Improved Representation and Personalized Aggregation"],"prefix":"10.1145","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2885-1608","authenticated-orcid":false,"given":"Qinghe","family":"Liu","sequence":"first","affiliation":[{"name":"The Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8335-214X","authenticated-orcid":false,"given":"Mingming","family":"Jiang","sequence":"additional","affiliation":[{"name":"The Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8697-9569","authenticated-orcid":false,"given":"Pin","family":"Wang","sequence":"additional","affiliation":[{"name":"Tianjin University, Tianjin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0335-1855","authenticated-orcid":false,"given":"Hongli","family":"Xu","sequence":"additional","affiliation":[{"name":"Chinese PLA General Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5293-0782","authenticated-orcid":false,"given":"Rilige","family":"Wu","sequence":"additional","affiliation":[{"name":"The Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7315-3276","authenticated-orcid":false,"given":"Zhenfeng","family":"Zhu","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Advanced Information Science and Network Technology, Beijing, China, and Institute of Information Science, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9066-1475","authenticated-orcid":false,"given":"Xinwang","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Computer Science, National University of Defense Technology, Changsha, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8352-0092","authenticated-orcid":false,"given":"Yawei","family":"Zhao","sequence":"additional","affiliation":[{"name":"The Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3335-5700","authenticated-orcid":false,"given":"Kunlun","family":"He","sequence":"additional","affiliation":[{"name":"The Medical Innovation Research Division, Chinese PLA General Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"320","published-online":{"date-parts":[[2025,11,21]]},"reference":[{"key":"e_1_3_2_2_2","unstructured":"Manoj Ghuhan Arivazhagan Vinay Aggarwal Aaditya Kumar Singh and Sunav Choudhary. 2019. 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