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Softw."],"published-print":{"date-parts":[[2025,12,31]]},"abstract":"<jats:p>\n                    This article presents updates to\n                    <jats:monospace>life<\/jats:monospace>\n                    <jats:sup>\n                      <jats:monospace>x<\/jats:monospace>\n                    <\/jats:sup>\n                    [Africa, SoftwareX (2022)], a\n                    <jats:monospace>C++<\/jats:monospace>\n                    library for high-performance finite element simulations of multiphysics, multiscale, and multidomain problems. In this release, we introduce an additional intergrid transfer method for non-matching multiphysics coupling on the same domain, significantly optimize nearest-neighbor point searches and interface coupling utilities, extend the support for 2D and mixed-dimensional problems, and provide improved facilities for input\/output and simulation serialization and restart. These advancements also propagate to the previously released modules of\n                    <jats:monospace>life<\/jats:monospace>\n                    <jats:sup>\n                      <jats:monospace>x<\/jats:monospace>\n                    <\/jats:sup>\n                    specifically designed for cardiac modeling and simulation, namely\n                    <jats:monospace>life<\/jats:monospace>\n                    <jats:sup>\n                      <jats:monospace>x<\/jats:monospace>\n                    <\/jats:sup>\n                    <jats:monospace>-fiber<\/jats:monospace>\n                    [Africa et al., BMC Bioinformatics (2023)],\n                    <jats:monospace>life<\/jats:monospace>\n                    <jats:sup>\n                      <jats:monospace>x<\/jats:monospace>\n                    <\/jats:sup>\n                    <jats:monospace>-ep<\/jats:monospace>\n                    [Africa et al., BMC Bioinformatics (2023)], and\n                    <jats:monospace>life<\/jats:monospace>\n                    <jats:sup>\n                      <jats:monospace>x<\/jats:monospace>\n                    <\/jats:sup>\n                    <jats:monospace>-cfd<\/jats:monospace>\n                    [Africa et al., Computer Physics Communications (2024)]. The changes introduced in this release aim at consolidating\n                    <jats:monospace>life<\/jats:monospace>\n                    <jats:sup>\n                      <jats:monospace>x<\/jats:monospace>\n                    <\/jats:sup>\n                    \u2019s position as a valuable and versatile tool for the simulation of multiphysics systems.\n                  <\/jats:p>","DOI":"10.1145\/3748817","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T16:35:54Z","timestamp":1757694954000},"page":"1-10","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["The lifex Library Version 2.0"],"prefix":"10.1145","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3089-9734","authenticated-orcid":false,"given":"Michele","family":"Bucelli","sequence":"first","affiliation":[{"name":"Dipartimento di Matematica, Politecnico di Milano, Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"320","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.softx.2022.101252"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpc.2023.109039"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-023-05260-w"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-023-05513-8"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1515\/jnma-2023-0089"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.camwa.2020.02.022"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cma.2024.116845"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10237-023-01735-0"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-024-03597-8"},{"key":"e_1_3_3_11_2","unstructured":"Boost. 2024. 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