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The study explores the psychological intervention effects of these animations on individuals experiencing anxiety and depression. Based on an interdisciplinary approach, a qualitative research methodology is employed, examining the fundamental theories and key issues of art therapy and patient psychology within the context of art therapy. A mixed-methods design was adopted, utilizing a specialized hospital as the implementation site for case studies. In-depth interviews were conducted with 15 patients, and 3D virtual reality (VR) ink-and-wash animations were developed based on their needs. A survey questionnaire was administered to 50 participants, and the results demonstrate that the application of immersive ink-and-wash animations in art therapy exhibits positive therapeutic effects. Among the 50 participants, anxiety scores decreased from 10.26 to 7.58 (a 26.1% reduction) after the intervention, and depression scores decreased from 11.14 to 8.36 (a 25.0% reduction), significantly improving their emotional states. Additionally, patients generally provided positive feedback on the natural imagery, traditional elements, and soft color tones within the ink-and-wash animations. Notably, middle-aged and elderly groups showed the most significant effects in terms of emotional regulation and psychological comfort. This study demonstrates that immersive art scenes, which merge traditional Chinese ink-and-wash aesthetics with digital multimedia technology, can effectively alleviate anxiety and depression symptoms. These scenes possess high emotional regulation value and cross-population adaptability, offering an innovative pathway for digital art therapy within an Eastern cultural context.<\/jats:p>","DOI":"10.1145\/3762998","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T15:01:35Z","timestamp":1756134095000},"page":"1-26","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Immersive Ink-and-Wash Landscape Design in Multimedia for Art Therapy"],"prefix":"10.1145","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5883-2828","authenticated-orcid":false,"given":"Jing","family":"Li","sequence":"first","affiliation":[{"name":"College of Art, Qingdao Agricultural University, Qingdao, China"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3864-2156","authenticated-orcid":false,"given":"Jun","family":"Guo","sequence":"additional","affiliation":[{"name":"College of Art, Qingdao Agricultural University, Qingdao, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5906-9422","authenticated-orcid":false,"given":"M. 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