{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T17:52:35Z","timestamp":1765389155605,"version":"3.46.0"},"publisher-location":"New York, NY, USA","reference-count":49,"publisher":"ACM","funder":[{"name":"Shriners Hospitals for Children"},{"name":"Wallace H. Coulter Distinguished Faculty Fellow"}],"content-domain":{"domain":["dl.acm.org"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10,12]]},"DOI":"10.1145\/3765612.3767236","type":"proceedings-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T17:45:59Z","timestamp":1765388759000},"page":"1-10","update-policy":"https:\/\/doi.org\/10.1145\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["KindSleep: Knowledge-Informed Diagnosis of Obstructive Sleep Apnea from Oximetry"],"prefix":"10.1145","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0915-6342","authenticated-orcid":false,"given":"Micky C","family":"Nnamdi","sequence":"first","affiliation":[{"name":"Georgia Institute of Technology, Atlanta, GA, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8972-7342","authenticated-orcid":false,"given":"Wenqi","family":"Shi","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center, Dallas, TX, USA"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5880-3242","authenticated-orcid":false,"given":"Cheng","family":"Wan","sequence":"additional","affiliation":[{"name":"Cornell University, Ithaca, NY, USA"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3780-1047","authenticated-orcid":false,"given":"J. Ben","family":"Tamo","sequence":"additional","affiliation":[{"name":"Georgia Institute of Technology, Atlanta, GA, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4035-9451","authenticated-orcid":false,"given":"Benjamin M","family":"Smith","sequence":"additional","affiliation":[{"name":"Shriners Children\u2019s, Tempa, FL, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8540-6269","authenticated-orcid":false,"given":"Chad A","family":"Purnell","sequence":"additional","affiliation":[{"name":"University of Illinois at Chicago, Chicago, IL, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3961-3608","authenticated-orcid":false,"given":"May Dongmei","family":"Wang","sequence":"additional","affiliation":[{"name":"Georgia Institute of Technology, Atlanta, GA, USA"}]}],"member":"320","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"key":"e_1_3_2_2_1_1","volume-title":"The health risk of obesity\u2014better metrics imperative. Science 341, 6148","author":"Ahima Rexford S","year":"2013","unstructured":"Rexford S Ahima and Mitchell A Lazar. 2013. The health risk of obesity\u2014better metrics imperative. Science 341, 6148 (2013), 856\u2013858."},{"key":"e_1_3_2_2_2_1","volume-title":"Ralf Seepold, and Juan Antonio Ortega.","author":"Alarc\u00f3n \u00c1ngel Serrano","year":"2023","unstructured":"\u00c1ngel Serrano Alarc\u00f3n, Natividad Mart\u00ednez Madrid, Ralf Seepold, and Juan Antonio Ortega. 2023. Obstructive sleep apnea event detection using explainable deep learning models for a portable monitor. Frontiers in neuroscience 17 (2023), 1155900."},{"key":"e_1_3_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0272167"},{"key":"e_1_3_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2011.03731.x"},{"key":"e_1_3_2_2_5_1","volume-title":"Diagnosis of obstructive sleep apnea in children: a systematic review. Sleep medicine reviews 17, 5","author":"Brockmann Pablo E","year":"2013","unstructured":"Pablo E Brockmann, Christine Schaefer, Anette Poets, Christian F Poets, and Michael S Urschitz. 2013. Diagnosis of obstructive sleep apnea in children: a systematic review. Sleep medicine reviews 17, 5 (2013), 331\u2013340."},{"key":"e_1_3_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.engappai.2023.106161"},{"key":"e_1_3_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/tee.23974"},{"key":"e_1_3_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200707-114MG"},{"key":"e_1_3_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.10190"},{"key":"e_1_3_2_2_10_1","volume-title":"Proceedings of machine learning research 252","author":"Fayyaz Hamed","year":"2024","unstructured":"Hamed Fayyaz, Niharika S D'Souza, and Rahmatollah Beheshti. 2024. Multimodal sleep apnea detection with missing or noisy modalities. Proceedings of machine learning research 252 (2024), https-proceedings."},{"key":"e_1_3_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1109\/RBME.2022.3185953"},{"key":"e_1_3_2_2_12_1","doi-asserted-by":"publisher","DOI":"10.1109\/BHI50953.2021.9508512"},{"key":"e_1_3_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.asoc.2021.107827"},{"key":"e_1_3_2_2_14_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.5776"},{"key":"e_1_3_2_2_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31819c74be"},{"key":"e_1_3_2_2_16_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.8160"},{"key":"e_1_3_2_2_17_1","volume-title":"International conference on machine learning. PMLR, 5338\u20135348","author":"Koh Pang Wei","year":"2020","unstructured":"Pang Wei Koh, Thao Nguyen, Yew Siang Tang, Stephen Mussmann, Emma Pierson, Been Kim, and Percy Liang. 2020. Concept bottleneck models. In International conference on machine learning. PMLR, 5338\u20135348."},{"key":"e_1_3_2_2_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40604-3"},{"key":"e_1_3_2_2_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/s22155560"},{"key":"e_1_3_2_2_20_1","volume-title":"A unified approach to interpreting model predictions. Advances in neural information processing systems 30","author":"Lundberg Scott M","year":"2017","unstructured":"Scott M Lundberg and Su-In Lee. 2017. A unified approach to interpreting model predictions. Advances in neural information processing systems 30 (2017)."},{"key":"e_1_3_2_2_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13838"},{"key":"e_1_3_2_2_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2020.09.019"},{"key":"e_1_3_2_2_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/diseases9040088"},{"key":"e_1_3_2_2_24_1","volume-title":"Claudio M Sanguinetti, and Fernando De Benedetto.","author":"Nardini Stefano","year":"2023","unstructured":"Stefano Nardini, Ulisse Corbanese, Alberto Visconti, Jacopo Dalle Mule, Claudio M Sanguinetti, and Fernando De Benedetto. 2023. Improving the management of patients with chronic cardiac and respiratory diseases by extending pulse-oximeter uses: the dynamic pulse-oximetry. Multidisciplinary Respiratory Medicine 18, 1 (2023)."},{"key":"e_1_3_2_2_25_1","doi-asserted-by":"publisher","DOI":"10.1145\/3584371.3613015"},{"key":"e_1_3_2_2_26_1","volume-title":"Concept Bottleneck Model for Adolescent Idiopathic Scoliosis Patient Reported Outcomes Prediction. In 2023 IEEE EMBS International Conference on Biomedical and Health Informatics (BHI). IEEE, 1\u20134.","author":"Nnamdi Micky C","year":"2023","unstructured":"Micky C Nnamdi, Wenqi Shi, J Ben Tamo, Henry J Iwinski, J Michael Wattenbarger, and May D Wang. 2023. Concept Bottleneck Model for Adolescent Idiopathic Scoliosis Patient Reported Outcomes Prediction. In 2023 IEEE EMBS International Conference on Biomedical and Health Informatics (BHI). IEEE, 1\u20134."},{"key":"e_1_3_2_2_27_1","first-page":"1077","article-title":"The sleep heart health study: design, rationale, and methods","volume":"20","author":"Quan Stuart F","year":"1997","unstructured":"Stuart F Quan, Barbara V Howard, Conrad Iber, James P Kiley, F Javier Nieto, George T O'Connor, David M Rapoport, Susan Redline, John Robbins, Jonathan M Samet, et al. 1997. The sleep heart health study: design, rationale, and methods. Sleep 20, 12 (1997), 1077\u20131085.","journal-title":"Sleep"},{"key":"e_1_3_2_2_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2003.08.031"},{"key":"e_1_3_2_2_29_1","volume-title":"The familial aggregation of obstructive sleep apnea. American journal of respiratory and critical care medicine 151, 3","author":"Redline Susan","year":"1995","unstructured":"Susan Redline, Peter V Tishler, Tor D Tosteson, John Williamson, Kenneth Kump, Ilene Browner, Veronica Ferrette, and Patrick Krejci. 1995. The familial aggregation of obstructive sleep apnea. American journal of respiratory and critical care medicine 151, 3 (1995), 682\u2013687."},{"key":"e_1_3_2_2_30_1","doi-asserted-by":"publisher","DOI":"10.1109\/ICCV.2017.74"},{"key":"e_1_3_2_2_31_1","volume-title":"Prevalence of obstructive sleep apnea in the general population: a systematic review. Sleep medicine reviews 34","author":"Senaratna Chamara V","year":"2017","unstructured":"Chamara V Senaratna, Jennifer L Perret, Caroline J Lodge, Adrian J Lowe, Brittany E Campbell, Melanie C Matheson, Garun S Hamilton, and Shyamali C Dharmage. 2017. Prevalence of obstructive sleep apnea in the general population: a systematic review. Sleep medicine reviews 34 (2017), 70\u201381."},{"key":"e_1_3_2_2_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43856-024-00726-1"},{"key":"e_1_3_2_2_33_1","doi-asserted-by":"publisher","DOI":"10.1109\/BHI50953.2021.9508574"},{"key":"e_1_3_2_2_34_1","volume-title":"Proceedings of the 2024 Conference on Empirical Methods in Natural Language Processing. Association for Computational Linguistics, 22315\u201322339","author":"Wenqi","year":"2024","unstructured":"Wenqi Shi*, Ran Xu*, Yuchen Zhuang, Yue Yu, Jieyu Zhang, Hang Wu, Yuanda Zhu, Joyce Ho, Carl Yang, and May D Wang. 2024. Ehragent: Code empowers large language models for few-shot complex tabular reasoning on electronic health records. In Proceedings of the 2024 Conference on Empirical Methods in Natural Language Processing. Association for Computational Linguistics, 22315\u201322339."},{"key":"e_1_3_2_2_35_1","doi-asserted-by":"publisher","DOI":"10.1109\/BIBM58861.2023.10385418"},{"key":"e_1_3_2_2_36_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.10930"},{"key":"e_1_3_2_2_37_1","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6579\/aaafb8"},{"key":"e_1_3_2_2_38_1","volume-title":"Nauman I Bhatti, Muhammad Arshad, Asher Ishaq, Muhammad Sajawal, Zoha Toor, and Osama Ahmad.","author":"Uzair Ahmed","year":"2024","unstructured":"Ahmed Uzair, Muhammad Waseem, Aun Bin Shahid, Nauman I Bhatti, Muhammad Arshad, Asher Ishaq, Muhammad Sajawal, Zoha Toor, and Osama Ahmad. 2024. Correlation Between Body Mass Index and Apnea-Hypopnea Index or Nadir Oxygen Saturation Levels in Patients With Obstructive Sleep Apnea. Cureus 16, 4 (2024)."},{"key":"e_1_3_2_2_39_1","volume-title":"Automated sleep apnea detection in raw respiratory signals using long short-term memory neural networks","author":"Steenkiste Tom Van","year":"2018","unstructured":"Tom Van Steenkiste, Willemijn Groenendaal, Dirk Deschrijver, and Tom Dhaene. 2018. Automated sleep apnea detection in raw respiratory signals using long short-term memory neural networks. IEEE journal of biomedical and health informatics 23, 6 (2018), 2354\u20132364."},{"key":"e_1_3_2_2_40_1","volume-title":"Hamid Reza Hassanzadeh, and May D Wang","author":"Venugopalan Janani","year":"2021","unstructured":"Janani Venugopalan, Li Tong, Hamid Reza Hassanzadeh, and May D Wang. 2021. Multimodal deep learning models for early detection of Alzheimer's disease stage. Scientific reports 11, 1 (2021), 3254."},{"key":"e_1_3_2_2_41_1","doi-asserted-by":"publisher","DOI":"10.1109\/OJEMB.2023.3347479"},{"key":"e_1_3_2_2_42_1","volume-title":"Advancing Sleep Disorder Diagnostics: A Transformer-based EEG Model for Sleep Stage Classification and OSA Prediction","author":"Wan Cheng","year":"2024","unstructured":"Cheng Wan, Micky C Nnamdi, Wenqi Shi, Benjamin Smith, Chad Purnell, and May D Wang. 2024. Advancing Sleep Disorder Diagnostics: A Transformer-based EEG Model for Sleep Stage Classification and OSA Prediction. IEEE Journal of Biomedical and Health Informatics (2024)."},{"key":"e_1_3_2_2_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-024-02606-z"},{"key":"e_1_3_2_2_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-024-02510-6"},{"key":"e_1_3_2_2_45_1","unstructured":"Ran Xu Yuchen Zhuang Yishan Zhong Yue Yu Xiangru Tang Hang Wu May D Wang Peifeng Ruan Donghan Yang Tao Wang et al. 2025. MedAgentGym: Training LLM Agents for Code-Based Medical Reasoning at Scale. arXiv preprint arXiv:2506.04405 (2025)."},{"key":"e_1_3_2_2_46_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2109080"},{"key":"e_1_3_2_2_47_1","volume-title":"Weakly Supervised Deep Learning for Monitoring Sleep Apnea Severity Using Coarsegrained Labels","author":"Zan Xin","year":"2025","unstructured":"Xin Zan, Di Wang, Changyue Song, Feng Liu, Xiaochen Xian, and Richard Berry. 2025. Weakly Supervised Deep Learning for Monitoring Sleep Apnea Severity Using Coarsegrained Labels. IEEE Transactions on Automation Science and Engineering (2025)."},{"key":"e_1_3_2_2_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocy064"},{"key":"e_1_3_2_2_49_1","doi-asserted-by":"crossref","unstructured":"Ying Y Zhao Rui Wang Kevin J Gleason Eldrin F Lewis Stuart F Quan Claudia M Toth Michael Morrical Michael Rueschman Jia Weng James H Ware et al. 2017. Effect of continuous positive airway pressure treatment on health-related quality of life and sleepiness in high cardiovascular risk individuals with sleep apnea: Best Apnea Interventions for Research (BestAIR) Trial. Sleep 40 4 (2017) zsx040.","DOI":"10.1093\/sleep\/zsx040"}],"event":{"name":"BCB '25: 16th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics","location":"Element Philadelphia Downtown Philadelphia PA USA","acronym":"BCB '25","sponsor":["SIGBio ACM Special Interest Group on Bioinformatics"]},"container-title":["Proceedings of the 16th ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics"],"original-title":[],"link":[{"URL":"https:\/\/dl.acm.org\/doi\/pdf\/10.1145\/3765612.3767236","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T17:47:59Z","timestamp":1765388879000},"score":1,"resource":{"primary":{"URL":"https:\/\/dl.acm.org\/doi\/10.1145\/3765612.3767236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,12]]},"references-count":49,"alternative-id":["10.1145\/3765612.3767236","10.1145\/3765612"],"URL":"https:\/\/doi.org\/10.1145\/3765612.3767236","relation":{},"subject":[],"published":{"date-parts":[[2025,10,12]]},"assertion":[{"value":"2025-12-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}