{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T04:43:51Z","timestamp":1793335431220,"version":"4.5.0"},"reference-count":90,"publisher":"Annual Reviews","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annu. Rev. Biophys. Biomol. Struct."],"published-print":{"date-parts":[[2000,6]]},"DOI":"10.1146\/annurev.biophys.29.1.1","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T11:49:00Z","timestamp":1027770540000},"page":"1-26","source":"Crossref","is-referenced-by-count":414,"title":["Measuring the Forces that Control Protein Interactions"],"prefix":"10.1146","volume":"29","author":[{"given":"Deborah","family":"Leckband","sequence":"first","affiliation":[{"name":"Department of Chemical Engineering and the Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801; e-mail:"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1038\/374539a0"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(95)80407-8"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(97)78161-X"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1126\/science.347575"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(84)84252-6"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.7.3694"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.3.2.157"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1021\/la950690y"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(95)80083-4"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.66.1.823"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.1038\/375104a0"},{"key":"b12","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1988.0038"},{"key":"b13","author":"Dori Y","year":"2000","journal-title":"Langmuir."},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.25.15782"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.49.30889"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(97)78802-7"},{"key":"b17","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(99)77399-6"},{"key":"b18","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(95)80441-8"},{"key":"b19","doi-asserted-by":"publisher","DOI":"10.1126\/science.8153628"},{"key":"b20","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.10.3.785"},{"key":"b21","doi-asserted-by":"publisher","DOI":"10.1038\/358347a0"},{"key":"b22","volume-title":"The Theory of Rate Processes.","author":"Glasstone S","year":"1941"},{"key":"b23","doi-asserted-by":"publisher","DOI":"10.1126\/science.271.5251.997"},{"key":"b24","doi-asserted-by":"publisher","DOI":"10.1006\/jcph.1999.6218"},{"key":"b25","doi-asserted-by":"publisher","DOI":"10.1021\/la981356f"},{"key":"b26","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(99)77221-8"},{"key":"b27","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.18.8169"},{"key":"b28","doi-asserted-by":"publisher","DOI":"10.1126\/science.7761829"},{"key":"b29","volume-title":"Foundations of Colloid Science.","author":"Hunter R","year":"1989"},{"key":"b30","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(97)78326-7"},{"key":"b31","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5729(92)90015-4"},{"key":"b32","volume-title":"Intermolecular and Surface Forces.","author":"Israelachvili J","year":"1992"},{"key":"b33","doi-asserted-by":"publisher","DOI":"10.1038\/379219a0"},{"key":"b34","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(97)78804-0"},{"key":"b35","volume-title":"Catalysis in Chemistry and Enzymology.","author":"Jencks WP","year":"1987"},{"key":"b36","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9797(91)90043-8"},{"key":"b37","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(93)81563-7"},{"key":"b38","doi-asserted-by":"publisher","DOI":"10.1126\/science.276.5315.1112"},{"key":"b39","doi-asserted-by":"crossref","unstructured":"Kennedy MT, Kisak E, Trommeshauser D, Zasadzinski JA. 2000. Self-limiting aggregation by controlled ligand-receptor stoichiometry. Submitted","DOI":"10.1021\/la990787a"},{"key":"b40","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.66.1.785"},{"key":"b41","doi-asserted-by":"crossref","first-page":"4426","DOI":"10.1016\/S0021-9258(18)34740-9","volume":"257","author":"Koppenol W","year":"1982","journal-title":"J. Biol. Chem."},{"key":"b42","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-8914(40)90098-2"},{"key":"b43","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(94)80938-5"},{"key":"b44","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(93)81277-3"},{"key":"b45","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1993.1644"},{"key":"b46","doi-asserted-by":"publisher","DOI":"10.1021\/bi00036a020"},{"key":"b47","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(95)79990-8"},{"key":"b48","doi-asserted-by":"publisher","DOI":"10.1021\/bi00181a023"},{"key":"b49","doi-asserted-by":"publisher","DOI":"10.1021\/la00014a003"},{"key":"b50","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(98)77556-3"},{"key":"b51","first-page":"662","volume":"75","author":"Lu H","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"b52","first-page":"1788","volume":"254","author":"Matsui K","year":"1991","journal-title":"Nature"},{"key":"b53","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-440X(98)80046-8"},{"key":"b54","doi-asserted-by":"publisher","DOI":"10.1126\/science.283.5408.1689"},{"key":"b55","doi-asserted-by":"publisher","DOI":"10.1038\/16219"},{"key":"b56","doi-asserted-by":"publisher","DOI":"10.1126\/science.7939660"},{"key":"b57","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(97)78195-5"},{"key":"b58","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(92)90112-Y"},{"key":"b59","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(96)79697-2"},{"key":"b60","doi-asserted-by":"publisher","DOI":"10.1038\/385537a0"},{"key":"b61","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.24.11460"},{"key":"b62","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.44.26586"},{"key":"b63","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.26.15114"},{"key":"b64","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.118.4.937"},{"key":"b65","doi-asserted-by":"publisher","DOI":"10.1126\/science.276.5315.1109"},{"key":"b66","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1998.2466"},{"key":"b67","doi-asserted-by":"publisher","DOI":"10.1016\/S0955-0674(96)80109-8"},{"key":"b68","doi-asserted-by":"publisher","DOI":"10.1139\/o95-048"},{"key":"b69","doi-asserted-by":"publisher","DOI":"10.1021\/bp960061u"},{"key":"b70","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bb.19.060190.001505"},{"key":"b71","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-679X(08)60400-8"},{"key":"b72","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.16.8399"},{"key":"b73","doi-asserted-by":"publisher","DOI":"10.1126\/science.284.5415.822"},{"key":"b74","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.83.652"},{"key":"b75","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.21.11820"},{"key":"b76","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.22.12961"},{"key":"b77","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bb.23.060194.001335"},{"key":"b78","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(97)78698-3"},{"key":"b79","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(93)81180-9"},{"key":"b80","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(86)83660-8"},{"key":"b81","doi-asserted-by":"publisher","DOI":"10.1038\/387308a0"},{"key":"b82","doi-asserted-by":"crossref","first-page":"4945","DOI":"10.1002\/j.1460-2075.1993.tb06188.x","volume":"12","author":"Van Der Merwe PA","year":"1993","journal-title":"EMBO J."},{"key":"b83","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(98)78032-4"},{"key":"b84","doi-asserted-by":"publisher","DOI":"10.1063\/1.476214"},{"key":"b85","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-440X(98)80041-9"},{"key":"b86","doi-asserted-by":"publisher","DOI":"10.1126\/science.275.5301.820"},{"key":"b87","doi-asserted-by":"publisher","DOI":"10.1021\/la970830z"},{"key":"b88","author":"Yeung C","year":"2000","journal-title":"Langmuir."},{"key":"b89","doi-asserted-by":"publisher","DOI":"10.1021\/bi9722756"},{"key":"b90","doi-asserted-by":"publisher","DOI":"10.1080\/00018739600101467"}],"container-title":["Annual Review of Biophysics and Biomolecular Structure"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.annualreviews.org\/doi\/pdf\/10.1146\/annurev.biophys.29.1.1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T07:33:44Z","timestamp":1622014424000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.annualreviews.org\/doi\/10.1146\/annurev.biophys.29.1.1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,6]]},"references-count":90,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,6]]}},"alternative-id":["10.1146\/annurev.biophys.29.1.1"],"URL":"https:\/\/doi.org\/10.1146\/annurev.biophys.29.1.1","relation":{},"ISSN":["1056-8700","1545-4266"],"issn-type":[{"value":"1056-8700","type":"print"},{"value":"1545-4266","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,6]]}}}