{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:12:10Z","timestamp":1791090730487,"version":"4.1.0"},"reference-count":92,"publisher":"Annual Reviews","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annu. Rev. Nutr."],"published-print":{"date-parts":[[1997,7]]},"abstract":"<jats:p>\u25aa Abstract\u2002 Many microorganisms previously unrecognized as food-borne or harmful are emerging as human pathogens transmitted by food. This is a result of recent acquisition of key virulence factors, detection by newly developed isolation procedures, or astute detective-like laboratory skills of microbiologists. Six microbial pathogens, including Shiga toxin-producing Escherichia coli, Listeria monocytogenes, Arcobacter butzleri, Helicobacter pylori, Cryptosporidium parvum, and Cyclospora, have become recognized as significant causes of human illness. Although the ecology and epidemiology of illness caused by some of these pathogens have not been fully elucidated, food has the potential of being an important vehicle in their dissemination. Existing technologies and new approaches such as irradiation and hazard analysis critical control point (HACCP) programs are useful tools in the control of food-borne hazards. However, because of ever-changing products, processes, food-handling practices, societal habits, and pathogens, emerging food-borne diseases will continue to be an important public health concern.<\/jats:p>","DOI":"10.1146\/annurev.nutr.17.1.255","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T11:45:50Z","timestamp":1027770350000},"page":"255-275","source":"Crossref","is-referenced-by-count":68,"title":["EMERGING ISSUES IN MICROBIOLOGICAL FOOD SAFETY"],"prefix":"10.1146","volume":"17","author":[{"given":"J.","family":"Meng","sequence":"first","affiliation":[{"name":"The Center for Food Safety and Quality Enhancement and the Department of Food Science and Technology, University of Georgia, Griffin, Georgia 30223,"},{"name":"Department of Nutrition and Food Science, University of Maryland, College Park, Maryland 20742;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. P.","family":"Doyle","sequence":"additional","affiliation":[{"name":"The Center for Food Safety and Quality Enhancement and the Department of Food Science and Technology, University of Georgia, Griffin, Georgia 30223-1797;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22","reference":[{"key":"b1","first-page":"302","volume":"62","author":"Acheson DWK","year":"1996","journal-title":"ASM News"},{"key":"b2","unstructured":"Adal KA, Sterling CR, Guerrant RL. 1995.Cryptosporidiumand related species. InInfections of the Gastrointestinal Tract,ed. MJ Blaser, PD Smith, JI Ravdin, HB Greenberg, RL Guerrant, pp. 1107\u201328. New York: Raven"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-199601000-00005"},{"key":"b4","first-page":"484","volume":"181","author":"Anderson BC","year":"1982","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1016\/S0934-8840(11)80898-4"},{"key":"b6","first-page":"380","volume":"127","author":"Aurich JE","year":"1990","journal-title":"Vet. Rec."},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199408000-00004"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.272.17.1349"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/170.2.272"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.269.17.2217"},{"key":"b11","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1128\/jcm.33.3.631-635.1995","volume":"33","author":"Beutin L","year":"1995","journal-title":"J. Clin. Microbiol."},{"key":"b12","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.1128\/jcm.31.9.2483-2488.1993","volume":"31","author":"Beutin L","year":"1993","journal-title":"J. Clin. Microbiol."},{"key":"b13","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1128\/aem.57.6.1624-1629.1991","volume":"57","author":"Boerlin P","year":"1991","journal-title":"Appl. Environ. Microbiol."},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(93)91069-T"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-56.4.297"},{"key":"b16","first-page":"118","volume":"62","author":"Calderwood SB","year":"1996","journal-title":"ASM News"},{"key":"b17","unstructured":"Caprioli A, Luzzi I, Minelli F, Benedetti I, Tozzi AE, et al. 1994. Hemolytic uremic syndrome and verotoxin-producingEscherichia coliinfection in Italy, 1988\u20131993. InRecent Advances in Verocytotoxin-Producing Escherichia coli Infections,ed. MA Karmali, AG Goglio, pp. 29\u201332. Amsterdam: Elsevier"},{"key":"b18","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/169.1.208"},{"key":"b19","first-page":"550","volume":"44","year":"1995","journal-title":"MMWR"},{"key":"b20","first-page":"157","volume":"44","year":"1995","journal-title":"MMWR"},{"key":"b21","first-page":"501","volume":"44","year":"1995","journal-title":"MMWR"},{"key":"b22","first-page":"459","volume":"45","year":"1996","journal-title":"MMWR"},{"key":"b23","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800057162"},{"key":"b24","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-59.5.448"},{"key":"b25","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199404000-00012"},{"key":"b26","unstructured":"Dalton CB, Austin C, Sobel J, Hayes P, Bibb B, et al. 1995. Outbreak of gastroenteritis fromListeria monocytogenes. InProc. 44th Annu. Epidemic Intell. Serv. Conf.pp. 19. Atlanta: CDC"},{"key":"b27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-765X.1996.tb00030.x"},{"key":"b28","doi-asserted-by":"crossref","first-page":"2394","DOI":"10.1128\/aem.53.10.2394-2396.1987","volume":"53","author":"Doyle MP","year":"1987","journal-title":"Appl. Environ. Microbiol."},{"key":"b29","volume-title":"Cryptosporidiosis of Man and Animals.","author":"Dubey JP","year":"1990"},{"key":"b30","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1128\/mr.55.3.476-511.1991","volume":"55","author":"Farber JM","year":"1991","journal-title":"Microbiol. Rev."},{"key":"b31","doi-asserted-by":"publisher","DOI":"10.3109\/00365549509047056"},{"key":"b32","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115893"},{"key":"b33","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.1128\/aem.58.8.2513-2516.1992","volume":"58","author":"Glass KA","year":"1992","journal-title":"Appl. Environ. Microbiol."},{"key":"b34","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-5-199603010-00001"},{"key":"b35","unstructured":"Goldwater PN, Bettelheim O. 1994. The role of enterohaemorrhagicE. coliserotypes other than O157:H7 as causes of disease. InRecent Advances in Verocytotoxin-Producing Escherichia coli Infections,ed. MA Karmali, AG Goglio, pp. 57\u201360. Amsterdam: Elsevier"},{"key":"b36","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/24.5.875"},{"key":"b37","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-4-199602150-00008"},{"key":"b38","doi-asserted-by":"publisher","DOI":"10.1016\/0168-1605(91)90070-6"},{"key":"b39","unstructured":"Griffin PM. 1995.Escherichia coliO157:H7 and other enterohemorrhagicEscherichia coli.InInfections of the Gastrointestinal Tract,ed. MJ Blaser, PD Smith, JI Ravdin, HB Greenberg, RL Guerrant, pp. 739\u201361. New York: Raven"},{"key":"b40","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.1128\/iai.62.6.2367-2374.1994","volume":"62","author":"Handt LK","year":"1994","journal-title":"Infect. Immun."},{"key":"b41","doi-asserted-by":"publisher","DOI":"10.1016\/0168-1605(92)90078-H"},{"key":"b42","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/168.1.222"},{"key":"b43","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-54.1.53"},{"key":"b44","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-123-6-199509150-00002"},{"key":"b45","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8612990"},{"key":"b46","doi-asserted-by":"publisher","DOI":"10.1016\/0168-1605(94)90133-3"},{"key":"b47","doi-asserted-by":"publisher","DOI":"10.1016\/S0934-8840(11)80542-6"},{"key":"b48","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1128\/aem.61.6.2242-2246.1995","volume":"61","author":"Jacquet C","year":"1995","journal-title":"Appl. Environ. Microbiol."},{"key":"b49","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/21.Supplement_1.S57"},{"key":"b50","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1128\/jcm.29.2.376-385.1991","volume":"29","author":"Kichlbauch JA","year":"1991","journal-title":"J. Clin. Microbiol."},{"key":"b51","first-page":"1","volume":"45","author":"Kramer MH","year":"1996","journal-title":"MMWR"},{"key":"b52","unstructured":"Kudoh Y, Kai A, Obata H, Kusunoki J, Monma C, et al. 1994. Epidemiological surveys on verotoxin-producingEscherichia coliinfections in Japan. InRecent Advances in Verocytotoxin-Producing Escherichia coli Infections,ed. MA Karmali, AG Goglio, pp. 53\u201356. Amsterdam: Elsevier"},{"key":"b53","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1128\/jcm.34.2.431-433.1996","volume":"34","author":"Kudva IT","year":"1996","journal-title":"J. Clin. Microbiol."},{"key":"b54","doi-asserted-by":"publisher","DOI":"10.3109\/00365529409105352"},{"key":"b55","doi-asserted-by":"publisher","DOI":"10.1007\/BF01973994"},{"key":"b56","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198809293191303"},{"key":"b57","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1128\/jcm.31.2.296-301.1993","volume":"31","author":"Mariani-Kurkdjian P","year":"1993","journal-title":"J. Clin. Microbiol."},{"key":"b58","doi-asserted-by":"publisher","DOI":"10.1007\/BF01963840"},{"key":"b59","doi-asserted-by":"publisher","DOI":"10.1016\/0924-2244(94)90102-3"},{"key":"b60","doi-asserted-by":"publisher","DOI":"10.1001\/jama.272.20.1592"},{"key":"b61","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199106000-00004"},{"key":"b62","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-59.2.202"},{"key":"b63","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1128\/aem.59.9.2817-2822.1993","volume":"59","author":"Norrung B","year":"1993","journal-title":"Appl. Environ. Microbiol."},{"key":"b64","first-page":"65","volume":"180","author":"O'Brien A","year":"1992","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"b65","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1128\/jcm.33.5.1267-1269.1995","volume":"33","author":"Ooi WW","year":"1995","journal-title":"J. Clin. Microbiol."},{"key":"b66","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199305063281804"},{"key":"b67","unstructured":"Patten KJ, Rose JB. 1995. Viability ofCryptosporidium parvumoocysts in beverages: correlation of in vitro excystation with inclusion or exclusion of fluorogenic vital dyes.Abstr. Annu. Meet. Int. Assoc. Milk Food Environ. Sanit., p. 67. Des Moines, IA: Int. Assoc. Milk, Food & Environ Sanit."},{"key":"b68","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/15.6.903"},{"key":"b69","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)90972-9"},{"key":"b70","doi-asserted-by":"publisher","DOI":"10.1001\/jama.267.15.2046"},{"key":"b71","doi-asserted-by":"publisher","DOI":"10.1016\/S0934-8840(11)80342-7"},{"key":"b72","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/173.2.440"},{"key":"b73","first-page":"88","volume":"132","author":"Rice DH","year":"1995","journal-title":"Vet. Rec."},{"key":"b74","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/170.3.693"},{"key":"b75","unstructured":"Riegg SJ, Dunn BE, Blaser MJ. 1995. Microbiology and pathogenesis ofHelicobacter pylori. InInfections of the Gastrointestinal Tract,ed. MJ Blaser, PD Smith, JI Ravdin, HB Greenberg, RL Guerrant, pp. 535\u201350. New York:Raven"},{"key":"b76","unstructured":"Rocourt J. 1994.Listeria monocytogenes: the state of the science.Dairy Food Environ. Sanit.14:70\u201382"},{"key":"b77","doi-asserted-by":"publisher","DOI":"10.1016\/0168-1605(94)00087-M"},{"key":"b78","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1128\/aem.60.3.1038-1040.1994","volume":"60","author":"Samadpour M","year":"1994","journal-title":"Appl. Environ. Microbiol."},{"key":"b79","doi-asserted-by":"crossref","first-page":"2958","DOI":"10.1128\/aem.60.8.2958-2962.1994","volume":"60","author":"Schoeni JL","year":"1994","journal-title":"Appl. Environ. Microbiol."},{"key":"b80","doi-asserted-by":"publisher","DOI":"10.1001\/jama.267.15.2041"},{"key":"b81","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1128\/aem.60.3.1025-1028.1994","volume":"60","author":"Seymour C","year":"1994","journal-title":"Appl. Environ. Microbiol."},{"key":"b82","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.82.5.742"},{"key":"b83","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-117-10-812"},{"key":"b84","doi-asserted-by":"publisher","DOI":"10.1001\/jama.273.14.1118"},{"key":"b85","unstructured":"Taylor DN, Parsonnet J. 1995. Epidemiology and natural history ofHelicobacter pyloriinfection. InInfections of the Gastrointestinal Tract,ed. MJ Blaser, PD Smith, JI Ravdin, HB Greenberg, RL Guerrant, pp. 551\u201363. New York: Raven"},{"key":"b86","doi-asserted-by":"crossref","first-page":"2335","DOI":"10.1128\/jcm.30.9.2335-2337.1992","volume":"30","author":"Vandamme P","year":"1992","journal-title":"J. Clin. Microbiol."},{"key":"b87","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-59.10.1127"},{"key":"b88","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.2460\/javma.1994.204.08.1168","volume":"204","author":"Whipp SC","year":"1994","journal-title":"J. Am. Vet. Med. Assoc."},{"key":"b89","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800058684"},{"key":"b90","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-57.9.780"},{"key":"b91","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1128\/aem.59.8.2526-2530.1993","volume":"59","author":"Zhao T","year":"1993","journal-title":"Appl. Environ. Microbiol."},{"key":"b92","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1128\/aem.61.4.1290-1293.1995","volume":"61","author":"Zhao T","year":"1995","journal-title":"Appl. Environ. Microbiol."}],"container-title":["Annual Review of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.annualreviews.org\/doi\/pdf\/10.1146\/annurev.nutr.17.1.255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,6]],"date-time":"2024-01-06T05:10:13Z","timestamp":1704517813000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.annualreviews.org\/doi\/10.1146\/annurev.nutr.17.1.255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,7]]},"references-count":92,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1997,7]]}},"alternative-id":["10.1146\/annurev.nutr.17.1.255"],"URL":"https:\/\/doi.org\/10.1146\/annurev.nutr.17.1.255","relation":{},"ISSN":["0199-9885","1545-4312"],"issn-type":[{"value":"0199-9885","type":"print"},{"value":"1545-4312","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,7]]}}}