{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T15:58:59Z","timestamp":1793980739478,"version":"4.8.0"},"reference-count":34,"publisher":"Radiological Society of North America (RSNA)","issue":"2","funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009709","name":"Stichting De Weijerhorst","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009709","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011097","name":"CARIM, School for Cardiovascular Diseases, Universiteit Maastricht","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016244","name":"Health Foundation Limburg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016244","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015758","name":"Novo Nordisk Farma","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015758","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1148\/radiol.2021202634","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T14:55:55Z","timestamp":1608648955000},"page":"384-392","source":"Crossref","is-referenced-by-count":65,"title":["Interplay of White Matter Hyperintensities, Cerebral Networks, and                    Cognitive Function in an Adult Population: Diffusion-Tensor Imaging in the                    Maastricht Study"],"prefix":"10.1148","volume":"298","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5819-0615","authenticated-orcid":false,"given":"Laura W. M.","family":"Vergoossen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5271-8060","authenticated-orcid":false,"given":"Jacobus F. A.","family":"Jansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2870-482X","authenticated-orcid":false,"given":"Thomas T.","family":"van Sloten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8752-3223","authenticated-orcid":false,"given":"Coen D. A.","family":"Stehouwer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2128-8029","authenticated-orcid":false,"given":"Nicolaas C.","family":"Schaper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4474-9665","authenticated-orcid":false,"given":"Anke","family":"Wesselius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1767-8814","authenticated-orcid":false,"given":"Pieter C.","family":"Dagnelie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2398-0609","authenticated-orcid":false,"given":"Sebastiaan","family":"K\u00f6hler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3221-2150","authenticated-orcid":false,"given":"Martin P. J.","family":"van Boxtel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7750-8249","authenticated-orcid":false,"given":"Abraham A.","family":"Kroon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4469-0763","authenticated-orcid":false,"given":"Joost J. A.","family":"de Jong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8113-7604","authenticated-orcid":false,"given":"Miranda T.","family":"Schram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7905-0681","authenticated-orcid":false,"given":"Walter H.","family":"Backes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1577","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(02)00190-4"},{"key":"r2","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2015.121"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.513176"},{"key":"r4","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001716"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.09.027"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200002)47:2<145::AID-ANA3>3.0.CO;2-P"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2020.04.001"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23032"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000612"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23857"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2001.0978"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.2337\/dc19-0762"},{"key":"r13","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.01.011"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2008.03.024"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.1038\/30918"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1186\/1753-4631-1-3"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2575"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.10.003"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.87.198701"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.05.049"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.1097\/01.rct.0000226397.43235.8b"},{"key":"r22","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2009.01.002"},{"key":"r23","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-014-9889-0"},{"key":"r24","doi-asserted-by":"publisher","DOI":"10.1037\/0033-295X.103.3.403"},{"key":"r25","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1553-10.2010"},{"key":"r26","volume-title":"Introduction to mediation, moderation, and conditional process analysis: a regression-based approach","author":"Hayes AF","year":"2013"},{"key":"r27","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-1132"},{"key":"r28","volume-title":"Neuropsychological assessment","author":"Lezak MD","year":"2004"},{"key":"r29","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2009.07.048"},{"key":"r30","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-015-1097-5"},{"key":"r31","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2019.00145"},{"key":"r32","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000144280.59178.78"},{"key":"r33","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.003602"},{"key":"r34","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2017.13"}],"container-title":["Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsna.org\/doi\/pdf\/10.1148\/radiol.2021202634","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T18:00:19Z","timestamp":1611597619000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsna.org\/doi\/10.1148\/radiol.2021202634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1148\/radiol.2021202634"],"URL":"https:\/\/doi.org\/10.1148\/radiol.2021202634","relation":{},"ISSN":["0033-8419","1527-1315"],"issn-type":[{"value":"0033-8419","type":"print"},{"value":"1527-1315","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2]]}}}