{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T01:23:30Z","timestamp":1791509010847,"version":"4.3.4"},"reference-count":34,"publisher":"Radiological Society of North America (RSNA)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiology"],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:p> Using CT normalized join-count to quantify emphysema voxel compactness, this study demonstrates its predictive capability for emphysema progression as quantified by CT lung density and decline in lung function and gas transfer in individuals with chronic obstructive pulmonary disease. <\/jats:p>","DOI":"10.1148\/radiol.233265","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T13:56:37Z","timestamp":1721138197000},"source":"Crossref","is-referenced-by-count":5,"title":["CT Chest Imaging Using Normalized Join-Count: Predicting Emphysema                     Progression in the CanCOLD Study"],"prefix":"10.1148","volume":"312","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2993-1656","authenticated-orcid":false,"given":"Sukhraj","family":"Virdee","sequence":"first","affiliation":[{"name":"From the Department of Physics, Toronto Metropolitan University, 350                     Victoria St, Kerr Hall South Bldg, Rm KHS-344, Toronto, ON, Canada M5B 2K3                     (S.V., M.K.); Center for Heart Lung Innovation, St Paul\u2019s Hospital,                     Vancouver, Canada (W.C.T., J.C.H., C.J.H., M.K.); and McGill University Health                     Centre, McGill University, Montreal, Canada (J.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9289-3595","authenticated-orcid":false,"given":"Wan C.","family":"Tan","sequence":"additional","affiliation":[{"name":"From the Department of Physics, Toronto Metropolitan University, 350                     Victoria St, Kerr Hall South Bldg, Rm KHS-344, Toronto, ON, Canada M5B 2K3                     (S.V., M.K.); Center for Heart Lung Innovation, St Paul\u2019s Hospital,                     Vancouver, Canada (W.C.T., J.C.H., C.J.H., M.K.); and McGill University Health                     Centre, McGill University, Montreal, Canada (J.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9930-1935","authenticated-orcid":false,"given":"James C.","family":"Hogg","sequence":"additional","affiliation":[{"name":"From the Department of Physics, Toronto Metropolitan University, 350                     Victoria St, Kerr Hall South Bldg, Rm KHS-344, Toronto, ON, Canada M5B 2K3                     (S.V., M.K.); Center for Heart Lung Innovation, St Paul\u2019s Hospital,                     Vancouver, Canada (W.C.T., J.C.H., C.J.H., M.K.); and McGill University Health                     Centre, McGill University, Montreal, Canada (J.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7649-038X","authenticated-orcid":false,"given":"Jean","family":"Bourbeau","sequence":"additional","affiliation":[{"name":"From the Department of Physics, Toronto Metropolitan University, 350                     Victoria St, Kerr Hall South Bldg, Rm KHS-344, Toronto, ON, Canada M5B 2K3                     (S.V., M.K.); Center for Heart Lung Innovation, St Paul\u2019s Hospital,                     Vancouver, Canada (W.C.T., J.C.H., C.J.H., M.K.); and McGill University Health                     Centre, McGill University, Montreal, Canada (J.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9765-3435","authenticated-orcid":false,"given":"Cameron J.","family":"Hague","sequence":"additional","affiliation":[{"name":"From the Department of Physics, Toronto Metropolitan University, 350                     Victoria St, Kerr Hall South Bldg, Rm KHS-344, Toronto, ON, Canada M5B 2K3                     (S.V., M.K.); Center for Heart Lung Innovation, St Paul\u2019s Hospital,                     Vancouver, Canada (W.C.T., J.C.H., C.J.H., M.K.); and McGill University Health                     Centre, McGill University, Montreal, Canada (J.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2951-784X","authenticated-orcid":false,"given":"Miranda","family":"Kirby","sequence":"additional","affiliation":[{"name":"From the Department of Physics, Toronto Metropolitan University, 350                     Victoria St, Kerr Hall South Bldg, Rm KHS-344, Toronto, ON, Canada M5B 2K3                     (S.V., M.K.); Center for Heart Lung Innovation, St Paul\u2019s Hospital,                     Vancouver, Canada (W.C.T., J.C.H., C.J.H., M.K.); and McGill University Health                     Centre, McGill University, Montreal, Canada (J.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the CanCOLD Collaborative Research Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathon","family":"Samet","sequence":"additional","affiliation":[{"name":"Keck School of Medicine of USC, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milo","family":"Puhan","sequence":"additional","affiliation":[{"name":"John Hopkins School of Public Health, Baltimore, MD"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qutayba","family":"Hamid","sequence":"additional","affiliation":[{"name":"McGill University, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"Baglole","sequence":"additional","affiliation":[{"name":"McGill University, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palmina","family":"Mancino","sequence":"additional","affiliation":[{"name":"McGill University, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Zhi","family":"Li","sequence":"additional","affiliation":[{"name":"McGill University, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Song","sequence":"additional","affiliation":[{"name":"McGill University, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Jensen","sequence":"additional","affiliation":[{"name":"McGill University, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin Mcdonald","family":"Smith","sequence":"additional","affiliation":[{"name":"McGill University, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvan","family":"Fortier","sequence":"additional","affiliation":[{"name":"Sherbrooke University, Sherbrooke, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"Dligui","sequence":"additional","affiliation":[{"name":"Sherbrooke University, Sherbrooke, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Chapman","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Duke","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea S","family":"Gershon","sequence":"additional","affiliation":[{"name":"University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J Mark","family":"Fitzgerald","sequence":"additional","affiliation":[{"name":"University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Sadatsafavi","sequence":"additional","affiliation":[{"name":"University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Lo","sequence":"additional","affiliation":[{"name":"UBC James Hogg Research Center, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Cheng","sequence":"additional","affiliation":[{"name":"UBC James Hogg Research Center, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Un","sequence":"additional","affiliation":[{"name":"UBC James Hogg Research Center, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Fung","sequence":"additional","affiliation":[{"name":"UBC James Hogg Research Center, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Haynes","sequence":"additional","affiliation":[{"name":"UBC James Hogg Research Center, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyun","family":"Zheng","sequence":"additional","affiliation":[{"name":"UBC James Hogg Research Center, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LingXiang","family":"Zou","sequence":"additional","affiliation":[{"name":"UBC James Hogg Research Center, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Comeau","sequence":"additional","affiliation":[{"name":"UBC James Hogg Research Center, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandie L","family":"Walker","sequence":"additional","affiliation":[{"name":"University of Calgary, Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis","family":"Dumonceaux","sequence":"additional","affiliation":[{"name":"University of Calgary, Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Hernandez","sequence":"additional","affiliation":[{"name":"University of Dalhousie, Halifax, NS, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Fulton","sequence":"additional","affiliation":[{"name":"University of Dalhousie, Halifax, NS, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn","family":"Aaron","sequence":"additional","affiliation":[{"name":"University of Ottawa, Ottawa, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy","family":"Vandemheen","sequence":"additional","affiliation":[{"name":"University of Ottawa, Ottawa, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"O\u2019Donnell","sequence":"additional","affiliation":[{"name":"Queen\u2019s University, Kingston, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"McNeil","sequence":"additional","affiliation":[{"name":"Queen\u2019s University, Kingston, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Whelan","sequence":"additional","affiliation":[{"name":"Queen\u2019s University, Kingston, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francois","family":"Maltais","sequence":"additional","affiliation":[{"name":"University of Laval, Quebec City, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia","family":"Brouillard","sequence":"additional","affiliation":[{"name":"University of Laval, Quebec City, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darcy","family":"Marciniuk","sequence":"additional","affiliation":[{"name":"University of Saskatchewan, Saskatoon, SK, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Clemens","sequence":"additional","affiliation":[{"name":"University of Saskatchewan, Saskatoon, SK, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet","family":"Baran","sequence":"additional","affiliation":[{"name":"University of Saskatchewan, Saskatoon, SK, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1577","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16855-4"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16900-6"},{"key":"r4","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00239-2023"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105482"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1016\/j.resinv.2016.03.006"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2007.04.016"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)92689-8"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.11110173"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2011.01.011"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2017.09.022"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.5.9901055"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.222786"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020200563"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2018.09.014"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.16.8829"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2021210198"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.3109\/15412555.2012.665520"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.1111\/resp.13012"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00080312"},{"issue":"1","key":"r22","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1164\/ajrccm\/136.1.225","volume":"136","author":"Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"r23","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.2.7633722"},{"key":"r24","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-009-1437-z"},{"key":"r25","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200804-040QC"},{"key":"r26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2008.01269.x"},{"key":"r27","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2021203531"},{"key":"r28","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(13)70006-7"},{"key":"r29","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200208-908PP"},{"key":"r30","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.112433"},{"key":"r31","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.145995"},{"key":"r32","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00523-2022"},{"key":"r33","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2015.01.008"},{"key":"r34","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.603197"},{"key":"r35","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2019-213525"},{"key":"r36","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-40950-8"}],"container-title":["Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsna.org\/doi\/pdf\/10.1148\/radiol.233265","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T21:36:25Z","timestamp":1737754585000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsna.org\/doi\/10.1148\/radiol.233265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,7,1]]}},"alternative-id":["10.1148\/radiol.233265"],"URL":"https:\/\/doi.org\/10.1148\/radiol.233265","relation":{},"ISSN":["0033-8419","1527-1315"],"issn-type":[{"value":"0033-8419","type":"print"},{"value":"1527-1315","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,1]]},"article-number":"e233265"}}