{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:28:30Z","timestamp":1787668110428,"version":"build-2736575974"},"reference-count":32,"publisher":"Radiological Society of North America (RSNA)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiology"],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:p>Across two independent clinical cohorts, a distinct progressive growth pattern associated with family history of lung cancer was identified in patients with incidental pure ground-glass nodules detected at low-dose chest CT.<\/jats:p>","DOI":"10.1148\/radiol.253139","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T13:47:43Z","timestamp":1787665663000},"source":"Crossref","is-referenced-by-count":0,"title":["Growth Patterns and Risk Stratification of Incidental Small Pure                     Ground-Glass Nodules across Independent Cohorts"],"prefix":"10.1148","volume":"320","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3483-3713","authenticated-orcid":false,"given":"Hao","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Taizhou Hospital of                     Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen St, Linhai                     317000, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3011-9825","authenticated-orcid":false,"given":"Xinyu","family":"Fu","sequence":"additional","affiliation":[{"name":"Dalian Medical University, Dalian, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2130-0999","authenticated-orcid":false,"given":"Minhua","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Enze Hospital, Taizhou                     Enze Medical Center, Linhai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0389-1406","authenticated-orcid":false,"given":"Zimin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Taizhou Hospital of                     Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen St, Linhai                     317000, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingyu","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Taizhou Hospital of Zhejiang                     Province Affiliated to Wenzhou Medical University, Linhai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7450-7588","authenticated-orcid":false,"given":"Sikai","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, National Cancer                     Center\/National Clinical Research Center for Cancer\/Cancer Hospital, Chinese                     Academy of Medical Sciences and Peking Union Medical College, Beijing,                     China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-7102-7283","authenticated-orcid":false,"given":"Cien","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Taizhou Hospital of                     Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen St, Linhai                     317000, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5687-4731","authenticated-orcid":false,"given":"Pengfei","family":"Sheng","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Taizhou Hospital of                     Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen St, Linhai                     317000, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9458-1691","authenticated-orcid":false,"given":"Zhongxiao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Jingjiang                     People\u2019s Hospital Affiliated to Yangzhou Medical University, Jingjiang,                     China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, The Second                     Affiliated Hospital, Jiaxing University, Jiaxing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4174-4586","authenticated-orcid":false,"given":"William C.","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology, Queen Elizabeth                     Hospital, Hong Kong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9891-2486","authenticated-orcid":false,"given":"Pasan","family":"Witharana","sequence":"additional","affiliation":[{"name":"Northern General Hospital, Sheffield, UK"},{"name":"Imperial College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8082-4347","authenticated-orcid":false,"given":"Dehua","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Taizhou Hospital of                     Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen St, Linhai                     317000, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6123-0959","authenticated-orcid":false,"given":"Jianfei","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Taizhou Hospital of                     Zhejiang Province Affiliated to Wenzhou Medical University, 150 Ximen St, Linhai                     317000, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1577","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"r2","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-020-00432-6"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2204.0023"},{"issue":"8","key":"r4","first-page":"CD013829","volume":"8","author":"Bonney A","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.0377"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2023.10.028"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2024.09.037"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2016.04.006"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2019.05.005"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)01694-4"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2025.0002"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2017161659"},{"key":"r13","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.250366"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.232558"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.1007\/s11604-022-01345-3"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2021.04.051"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2501"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/syac081"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-024-03245-x"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v067.i01"},{"key":"r21","doi-asserted-by":"crossref","unstructured":"Geraci M. Linear                         quantile mixed models: the lqmm package for Laplace quantile                         regression. J Stat                         Soft 2014;57(13):1\u201329.","DOI":"10.18637\/jss.v057.i13"},{"key":"r22","doi-asserted-by":"publisher","DOI":"10.32614\/RJ-2017-066"},{"key":"r23","unstructured":"Therneau TM. coxme:                         mixed effects Cox models. Comprehensive R                         Archive Network. https:\/\/cran.r-project.org\/web\/packages\/coxme\/index.html.                         Published 2022. Accessed August 22, 2024."},{"key":"r24","unstructured":"Harrell FE Jr. rms:                         regression modeling strategies. Comprehensive                         R Archive Network. https:\/\/cran.r-project.org\/web\/packages\/rms\/index.html.                         Published 2023. Accessed February 18,                     2026."},{"key":"r25","author":"Proust-Lima C","journal-title":"Comprehensive R Archive Network"},{"key":"r26","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2015141071"},{"key":"r27","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20180204"},{"key":"r28","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2023.01.014"},{"key":"r29","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.251524"},{"key":"r30","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.251310"},{"key":"r31","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.250874"},{"key":"r32","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2021.102287"}],"container-title":["Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsna.org\/doi\/pdf\/10.1148\/radiol.253139","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T13:47:51Z","timestamp":1787665671000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsna.org\/doi\/10.1148\/radiol.253139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,1]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,8,1]]}},"alternative-id":["10.1148\/radiol.253139"],"URL":"https:\/\/doi.org\/10.1148\/radiol.253139","relation":{},"ISSN":["0033-8419","1527-1315"],"issn-type":[{"value":"0033-8419","type":"print"},{"value":"1527-1315","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,1]]},"article-number":"e253139"}}