{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:51:10Z","timestamp":1785855070793,"version":"3.56.0"},"reference-count":34,"publisher":"Radiological Society of North America (RSNA)","issue":"2","funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2024-00337298"],"award-info":[{"award-number":["RS-2024-00337298"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["RS-2024-00438542"],"award-info":[{"award-number":["RS-2024-00438542"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiology"],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:p>In patients with advanced hepatocellular carcinoma, after atezolizumab-bevacizumab failure, second-line hepatic arterial infusion chemotherapy yielded higher response rates and longer progression-free survival than tyrosine kinase inhibitors.<\/jats:p>","DOI":"10.1148\/radiol.253280","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T13:59:50Z","timestamp":1785851990000},"source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Second-line Hepatic Arterial Infusion Chemotherapy and                     Tyrosine Kinase Inhibitors in Advanced Hepatocellular Carcinoma"],"prefix":"10.1148","volume":"320","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7875-6486","authenticated-orcid":false,"given":"Jae-Sung","family":"Yoo","sequence":"first","affiliation":[{"name":"Department of Medicine, Graduate School, Kyungpook                     National University, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1512-0948","authenticated-orcid":false,"given":"Kwon Yong","family":"Tak","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Seoul St. Mary\u2019s Hospital, The Catholic University                     of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6587-5081","authenticated-orcid":false,"given":"Hee Sun","family":"Cho","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Seoul St. Mary\u2019s Hospital, The Catholic University                     of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1456-1450","authenticated-orcid":false,"given":"Ji Won","family":"Han","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Seoul St. Mary\u2019s Hospital, The Catholic University                     of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Won","family":"Jang","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Seoul St. Mary\u2019s Hospital, The Catholic University                     of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4402-9350","authenticated-orcid":false,"given":"Jaejun","family":"Lee","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Eunpyeong St. Mary\u2019s Hospital, College of Medicine,                     The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6588-9806","authenticated-orcid":false,"given":"Hyun","family":"Yang","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Eunpyeong St. Mary\u2019s Hospital, College of Medicine,                     The Catholic University of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1184-0358","authenticated-orcid":false,"given":"Chang Wook","family":"Kim","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Uijeongbu St. Mary\u2019s Hospital, College of Medicine,                     The Catholic University of Korea, Uijeongbu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hae Lim","family":"Lee","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Bucheon St. Mary\u2019s Hospital, College of Medicine,                     The Catholic University of Korea, Bucheon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee Yeon","family":"Kim","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Bucheon St. Mary\u2019s Hospital, College of Medicine,                     The Catholic University of Korea, Bucheon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2217-009X","authenticated-orcid":false,"given":"Suho","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology, Seoul St Mary\u2019s Hospital,                     College of Medicine, The Catholic University of Korea, Seoul, Republic of                     Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Suk","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Radiology, Seoul St Mary\u2019s Hospital,                     College of Medicine, The Catholic University of Korea, Seoul, Republic of                     Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho Jong","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Radiology, Seoul St Mary\u2019s Hospital,                     College of Medicine, The Catholic University of Korea, Seoul, Republic of                     Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5421-6868","authenticated-orcid":false,"given":"Heechul","family":"Nam","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Uijeongbu St. Mary\u2019s Hospital, College of Medicine,                     The Catholic University of Korea, Uijeongbu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5780-9607","authenticated-orcid":false,"given":"Pil Soo","family":"Sung","sequence":"additional","affiliation":[{"name":"The Catholic University Liver Research Center, Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea"},{"name":"Division of Gastroenterology and Hepatology, Department                     of Internal Medicine, Seoul St. Mary\u2019s Hospital, The Catholic University                     of Korea, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1577","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1915745"},{"key":"r2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2025.10.020"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2023.0553"},{"key":"r4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30207-1"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0708857"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1159\/000367746"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i13.3843"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2022.0402"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.5009\/gnl19367"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.13542"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2019.0250"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2022.0391"},{"key":"r13","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(18)30078-5"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10184045"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1085166"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1247132"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-010-0917-5"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27290"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.00608"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.5009\/gnl250532"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.4103\/jcrt.JCRT_898_19"},{"key":"r22","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2016.322"},{"key":"r23","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.00392"},{"key":"r24","doi-asserted-by":"publisher","DOI":"10.2147\/JHC.S477872"},{"key":"r25","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol32060313"},{"key":"r26","doi-asserted-by":"publisher","DOI":"10.1159\/000533493"},{"key":"r27","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2024.1495321"},{"key":"r28","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-024-04308-6"},{"key":"r29","doi-asserted-by":"publisher","DOI":"10.17998\/jlc.19.1.64"},{"key":"r30","doi-asserted-by":"publisher","DOI":"10.17998\/jlc.2022.03.04"},{"key":"r31","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2022.106556"},{"key":"r32","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-020-03221-2"},{"key":"r33","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1291530"},{"key":"r34","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00978"}],"container-title":["Radiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsna.org\/doi\/pdf\/10.1148\/radiol.253280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:00:12Z","timestamp":1785852012000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsna.org\/doi\/10.1148\/radiol.253280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,1]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,8,1]]}},"alternative-id":["10.1148\/radiol.253280"],"URL":"https:\/\/doi.org\/10.1148\/radiol.253280","relation":{},"ISSN":["0033-8419","1527-1315"],"issn-type":[{"value":"0033-8419","type":"print"},{"value":"1527-1315","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,1]]},"article-number":"e253280"}}