{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T00:29:05Z","timestamp":1781915345206,"version":"3.54.5"},"reference-count":102,"publisher":"Radiological Society of North America (RSNA)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["RadioGraphics"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1148\/rg.2018180047","type":"journal-article","created":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T16:59:53Z","timestamp":1539363593000},"page":"1902-1920","source":"Crossref","is-referenced-by-count":53,"title":["Breast Cancer Tissue Markers, Genomic Profiling, and Other Prognostic Factors: A Primer for Radiologists"],"prefix":"10.1148","volume":"38","author":[{"given":"Nikki","family":"Tirada","sequence":"first","affiliation":[{"name":"From the Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mireille","family":"Aujero","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gauri","family":"Khorjekar","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Richards","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasleen","family":"Chopra","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Dromi","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Ioffe","sequence":"additional","affiliation":[{"name":"From the Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1577","reference":[{"key":"r1","unstructured":"Noone AM, Howlader N, Krapcho M, et al, eds. SEER Cancer Statistics Review, 1975-2015. National Cancer Institute. Bethesda, MD. https:\/\/seer.cancer.gov\/csr\/1975_2015\/. Published April 2018. Accessed September 18, 2018."},{"key":"r2","unstructured":"American Cancer Society. Cancer facts and figures 2017. Atlanta, Ga: American Cancer Society, 2017."},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.1053\/ctrv.2000.0207"},{"key":"r4","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.9-6-606"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1007\/BF00666054"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-40618-3"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007695"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.2471"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0030025"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02292-3"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.44.1956"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.21.2492"},{"key":"r13","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-007-9632-6"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.63.9328"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-007-9785-3"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-010-0990-0"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.29.7614"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2014.02.009"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.1148\/rg.344140140"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604368"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dji239"},{"key":"r22","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.9.1064"},{"issue":"1","key":"r23","first-page":"18","volume":"2","author":"Ballard LJ","year":"2013","journal-title":"J Am Osteopath Coll Radiol"},{"key":"r24","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e7536"},{"key":"r25","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2015.2510"},{"key":"r26","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djs327"},{"key":"r27","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa062790"},{"key":"r28","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2301020589"},{"key":"r29","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-04-0327"},{"key":"r30","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050025"},{"key":"r31","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-09-1028"},{"key":"r32","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604989"},{"key":"r33","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19890101)63:1<181::AID-CNCR2820630129>3.0.CO;2-H"},{"key":"r34","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11765"},{"key":"r35","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0b013e31822d9cd6"},{"key":"r36","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds136"},{"key":"r37","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-010-0917-9"},{"key":"r38","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyg031"},{"key":"r39","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(89)90529-4"},{"key":"r40","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1990.8.1.113"},{"key":"r41","doi-asserted-by":"publisher","DOI":"10.1080\/02841860600602953"},{"key":"r42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2014.04.003"},{"key":"r43","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4741.1999.00003.x"},{"key":"r44","doi-asserted-by":"publisher","DOI":"10.1111\/j.1075-122X.2004.21279.x"},{"key":"r45","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.2820741336"},{"key":"r46","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20083"},{"key":"r47","doi-asserted-by":"publisher","DOI":"10.3816\/CBC.2004.n.042"},{"key":"r48","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(02)04201-3"},{"key":"r49","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(94)90115-5"},{"key":"r50","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-016-2281-6"},{"key":"r51","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.10.147"},{"key":"r52","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.01.039"},{"key":"r53","unstructured":"Lakhani SR, Ellis IO, Schnitt SJ, Tan PH, van de Vijver MJ. WHO classification of tumours of the breast. 4th ed. Lyon, France: IARC, 2012."},{"key":"r54","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21387"},{"key":"r55","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2016.283"},{"key":"r56","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.5001"},{"key":"r57","doi-asserted-by":"publisher","DOI":"10.1148\/rg.2017160166"},{"key":"r58","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20515"},{"key":"r59","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70207-2"},{"key":"r60","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1034"},{"key":"r61","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.25710"},{"key":"r62","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3847-4"},{"key":"r63","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197507)36:1<1::AID-CNCR2820360102>3.0.CO;2-4"},{"key":"r64","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25942"},{"key":"r65","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-009-0360-y"},{"key":"r66","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.9336"},{"key":"r69","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.14140594"},{"key":"r70","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1991.tb00229.x"},{"key":"r71","doi-asserted-by":"publisher","DOI":"10.1016\/S1040-8428(99)00034-7"},{"key":"r72","unstructured":"Hoda SA, Brogi E, Koerner FC, Rosen PP. Rosen\u2019s breast pathology. 4th ed. Philadelphia, Pa: Lippincott Williams & Wilkins, 2014."},{"key":"r73","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2013.756"},{"key":"r74","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.6529"},{"key":"r75","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052306"},{"key":"r76","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.50.9984"},{"key":"r77","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2011.201"},{"key":"r78","doi-asserted-by":"publisher","DOI":"10.20892\/j.issn.2095-3941.2016.0066"},{"key":"r79","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath-2017-204976"},{"key":"r80","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr304"},{"key":"r81","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdv221"},{"key":"r82","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djr393"},{"key":"r83","doi-asserted-by":"publisher","DOI":"10.1038\/35021093"},{"key":"r84","doi-asserted-by":"publisher","DOI":"10.1148\/rg.345130049"},{"key":"r85","doi-asserted-by":"publisher","DOI":"10.7150\/jca.13141"},{"key":"r86","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp082"},{"key":"r87","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-013-2647-2"},{"issue":"24","key":"r88","first-page":"S5","volume":"72","author":"Romond E","year":"2012","journal-title":"Cancer Res"},{"key":"r89","doi-asserted-by":"publisher","DOI":"10.1186\/bcr2635"},{"key":"r90","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2007-8-8-r157"},{"issue":"9","key":"r91","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1177\/000313480507100906","volume":"71","author":"Gibson GR","year":"2005","journal-title":"Am Surg"},{"key":"r93","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050518"},{"key":"r94","doi-asserted-by":"publisher","DOI":"10.3816\/CBC.2006.n.051"},{"key":"r95","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.74.0472"},{"key":"r96","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2006.076497"},{"key":"r97","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.4798"},{"key":"r98","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-015-3464-6"},{"key":"r99","doi-asserted-by":"publisher","DOI":"10.1038\/415530a"},{"key":"r100","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.3222"},{"key":"r101","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.4.980"},{"key":"r102","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66544-0"},{"key":"r103","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-0926"},{"key":"r104","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2013.671"},{"key":"r105","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djw149"}],"container-title":["RadioGraphics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.rsna.org\/doi\/pdf\/10.1148\/rg.2018180047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T00:00:27Z","timestamp":1605225627000},"score":1,"resource":{"primary":{"URL":"http:\/\/pubs.rsna.org\/doi\/10.1148\/rg.2018180047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":102,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["10.1148\/rg.2018180047"],"URL":"https:\/\/doi.org\/10.1148\/rg.2018180047","relation":{},"ISSN":["0271-5333","1527-1323"],"issn-type":[{"value":"0271-5333","type":"print"},{"value":"1527-1323","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11]]}}}