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Muscarine also reduced the amplitude of the slow afterhyperpolarization (sAHP) following action potentials in most DA neurons. These data suggest that muscarine reduces Ca<jats:sup>2+<\/jats:sup>entry in SNc DA neurons. The reduction of the amplitude of the sAHP by muscarine in DA neurons may facilitate bursting initiated by glutamatergic input by increasing the frequency at which DA neurons can fire. The reduction of the sAHP via activation of muscarinic receptors in vivo may provide a mechanism whereby cholinergic inputs to DA neurons from the tegmental peduncular pontine nucleus could modulate dopamine release at dopaminergic targets in the brain.<\/jats:p>","DOI":"10.1152\/jn.2001.86.6.2966","type":"journal-article","created":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T11:06:05Z","timestamp":1513854365000},"page":"2966-2972","source":"Crossref","is-referenced-by-count":30,"title":["Muscarine Reduces Calcium-Dependent Electrical Activity in Substantia Nigra Dopaminergic Neurons"],"prefix":"10.1152","volume":"86","author":[{"given":"Reese S.","family":"Scroggs","sequence":"first","affiliation":[{"name":"Department of Anatomy and Neurobiology, Health Science Center, University of Tennessee, Memphis, Tennessee 38163; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla G.","family":"Cardenas","sequence":"additional","affiliation":[{"name":"Department 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