{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:47:37Z","timestamp":1787017657840,"version":"build-2736575974"},"reference-count":671,"publisher":"American Physiological Society","issue":"4","funder":[{"name":"Serb Pharmaceuticals\/BTG Pharmaceuticals","award":["Clinical Trial Contract"],"award-info":[{"award-number":["Clinical Trial Contract"]}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Cell Physiology"],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:p>\n                    Cardiotonic steroids (CTS), used by certain insects, toads, and rats for protection from predators, became, thanks to Withering\u2019s trailblazing 1785 monograph, the mainstay of heart failure (HF) therapy. In the 1950s and 1960s, we learned that the CTS receptor was part of the sodium pump (NKA) and that the Na\n                    <jats:sup>+<\/jats:sup>\n                    \/Ca\n                    <jats:sup>2+<\/jats:sup>\n                    exchanger was critical for the acute cardiotonic effect of digoxin- and ouabain-related CTS. This \u201csettled\u201d view was upended by seven revolutionary observations. First, subnanomolar ouabain sometimes stimulates NKA while higher concentrations are invariably inhibitory. Second, endogenous ouabain (EO) was discovered in the human circulation. Third, in the DIG clinical trial, digoxin only marginally improved outcomes in patients with HF. Fourth, cloning of NKA in 1985 revealed multiple NKA \u03b1 and \u03b2 subunit isoforms that, in the rodent, differ in their sensitivities to CTS. Fifth, the NKA is a cation pump and a hormone receptor\/signal transducer. EO binding to NKA activates, in a ligand- and cell-specific manner, several protein kinase and Ca\n                    <jats:sup>2+<\/jats:sup>\n                    -dependent signaling cascades that have widespread physiological effects and can contribute to hypertension and HF pathogenesis. Sixth, all CTS are not equivalent, e.g., ouabain induces hypertension in rodents while digoxin is antihypertensinogenic (\u201cbiased signaling\u201d). Seventh, most common rodent hypertension models require a highly ouabain-sensitive \u03b12 NKA and the elevated blood pressure is alleviated by EO immunoneutralization. These numerous phenomena are enabled by NKA\u2019s intricate structure. We have just begun to understand the endocrine role of the endogenous ligands and the broad impact of the ouabain-binding site on physiology and pathophysiology.\n                  <\/jats:p>","DOI":"10.1152\/ajpcell.00273.2023","type":"journal-article","created":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T04:38:38Z","timestamp":1705293518000},"page":"C1120-C1177","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":34,"title":["Sensational site: the sodium pump ouabain-binding site and its ligands"],"prefix":"10.1152","volume":"326","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2926-710X","authenticated-orcid":false,"given":"Mordecai P.","family":"Blaustein","sequence":"first","affiliation":[{"name":"Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, United States"},{"name":"Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5875-4807","authenticated-orcid":false,"given":"John M.","family":"Hamlyn","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.201812274"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.50.4.893"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.54.5.650"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0099413"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.81645"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.17.10372"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1033.2002.02910.x"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2020.102159"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1043"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2020.102210"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2016.00179"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00347.2016"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.00895"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2020.01.008"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(57)90343-8"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-021909-135725"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.00371"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.103.4.605"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.46.30826"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1038\/srep20442"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(78)90654-9"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)50519-6"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.jbchem.a132654"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2003.tb07214.x"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-10-03488.1997"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1999.277.5.C891"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)89442-5"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1021\/bi991207b"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gal062"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1007\/pl00005899"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.1998.275.5.F633"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1994.1136"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.1996.271.2.F253"},{"key":"B34","first-page":"229","volume":"607","author":"Hansen O","year":"1992","journal-title":"Acta Physiol Scand Suppl"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1994.267.4.C901"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)50229-0"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2001.281.3.R917"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1007\/s10863-007-9107-9"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00275.2017"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)83179-9"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5584-12.2013"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1002\/cphy.c200018"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00539.2015"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00126.2005"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.202012660"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.202012633"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.202012845"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2003.tb07220.x"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M512063200"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.2000.279.3.C541"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2010.04.035"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0265-19.2019"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1998.0904"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-012-1039-9"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222413268"},{"key":"B56","first-page":"346","volume":"11","author":"Schatzmann HJ","year":"1953","journal-title":"Helv Physiol Pharmacol Acta"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1957.sp005749"},{"key":"B58","first-page":"381","volume":"16","author":"Glynn IM","year":"1964","journal-title":"Pharmacol Rev"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.83.3.395"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1021\/bi800445f"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2013.266866"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M402778200"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.jbchem.a002862"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291x(80)91098-0"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13091385"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.3390\/toxins10080336"},{"key":"B67","first-page":"526","volume":"6","author":"Cule J","year":"1963","journal-title":"J Coll Gen Pract"},{"key":"B68","volume-title":"De Historia Stirpium Commentarii Insignes","author":"Fuchs L","year":"1542"},{"key":"B69","unstructured":"Withering W. An Account of the Foxglove and Some of its Medical Uses. Birmingham: G.G.J. and J. Robinson, 1785, p. 207."},{"key":"B70","doi-asserted-by":"crossref","unstructured":"Fraser TR. Strophanthus Hispidus: Its Natural History, Chemistry, and Pharmacology. Edinburgh: Neill & Co. 1891, p. 190.","DOI":"10.1017\/S037016460000612X"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.1298.904"},{"key":"B72","first-page":"1011","volume":"106","author":"Arnaud A","year":"1888","journal-title":"Compt Rendus"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1039\/JR9300000508"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1951.sp004509"},{"key":"B75","volume-title":"Chemical Physiology of Contraction in Body and Heart Muscle","author":"Szent-Gyorgi A","year":"1953"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1172\/JCI103377"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(60)90746-0"},{"key":"B78","first-page":"409","volume":"10","author":"Wilbrandt W","year":"1960","journal-title":"Arzneimittelforschung"},{"key":"B79","first-page":"47","volume-title":"New Aspects of Cardiac Glycosides Proceedings of the 1st International Pharmacological Meeting","author":"Repke K","year":"1963"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1969.sp008702"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1084\/jem.129.3.507"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(76)90284-8"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1977.232.5.C165"},{"key":"B84","doi-asserted-by":"crossref","first-page":"I167","DOI":"10.1161\/01.RES.46.2.167","volume":"46","author":"Thomas R","year":"1980","journal-title":"Circ Res"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1038\/300650a0"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(84)90158-9"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1038\/316691a0"},{"key":"B88","first-page":"667","volume-title":"The Sodium Pump","author":"Hamlyn JM","year":"1985"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1021\/bi00422a016"},{"key":"B90","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-291x(05)80898-8"},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.14.6259"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.86.2.420"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(92)81530-y"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.22.2.178"},{"key":"B95","volume":"22","author":"Manunta P","year":"1993","journal-title":"Hypertension"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.23.supplement_s77"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1993.tb18141.x"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1993.264.3.E413"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1210\/endo.135.2.8033829"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1161\/01.res.74.4.586"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199510000-00013"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.24.15249"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.27.19323"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1997.00488.x"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.1016\/s0303-7207(96)03964-0"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.29.1.401"},{"key":"B107","first-page":"83","volume":"285","author":"Ferrari P","year":"1998","journal-title":"J Pharmacol Exp Ther"},{"key":"B108","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2003.08.006"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507358102"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2004.08.005"},{"key":"B111","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.10.067"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200704959"},{"key":"B113","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0907054106"},{"key":"B114","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3001814"},{"key":"B115","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00532.2011"},{"key":"B116","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00594.2012"},{"key":"B117","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00337.2012"},{"key":"B118","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0108916"},{"key":"B119","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2014020130"},{"key":"B120","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1422997112"},{"key":"B121","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2020438118"},{"key":"B122","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2123226119"},{"key":"B123","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.ade5393"},{"key":"B124","first-page":"370","volume":"97","author":"Ziskind B","year":"2004","journal-title":"Arch Mal Coeur Vaiss"},{"key":"B125","doi-asserted-by":"publisher","DOI":"10.2174\/1381612823666170925163427"},{"key":"B126","first-page":"119","author":"Norn S","year":"2004","journal-title":"Dan Medicinhist Arbog"},{"key":"B127","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2009.08.001"},{"key":"B128","unstructured":"Estes JW. Hall Jackson and the Purple Foxglove. Hanover, NH: University Press of New England, 1979, p. 291."},{"key":"B129","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199702203360801"},{"key":"B130","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(93)90403-n"},{"key":"B131","doi-asserted-by":"publisher","DOI":"10.1016\/s0735-1097(02)01708-4"},{"key":"B132","doi-asserted-by":"publisher","DOI":"10.1016\/s0025-7125(02)00172-4"},{"key":"B133","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.06.068"},{"key":"B134","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2015.07.003"},{"key":"B135","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00362.2022"},{"key":"B136","doi-asserted-by":"publisher","DOI":"10.1016\/s0735-1097(83)80080-1"},{"key":"B137","doi-asserted-by":"publisher","DOI":"10.1016\/0378-8741(92)90071-x"},{"key":"B138","first-page":"139","volume":"7","author":"Fraser TR","year":"1872","journal-title":"J Anat Physiol"},{"key":"B139","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0000000000000151"},{"key":"B140","doi-asserted-by":"publisher","DOI":"10.1378\/chest.63.1.2"},{"key":"B141","volume-title":"The Merck Index","author":"Windholz M","year":"1976","edition":"9"},{"key":"B142","doi-asserted-by":"publisher","DOI":"10.1038\/199910a0"},{"key":"B143","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1969.sp008703"},{"key":"B144","doi-asserted-by":"publisher","DOI":"10.3390\/insects10040102"},{"key":"B145","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2024463118"},{"key":"B146","doi-asserted-by":"publisher","DOI":"10.3390\/insects9040150"},{"key":"B147","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1610-8"},{"key":"B148","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1202111109"},{"key":"B149","doi-asserted-by":"publisher","DOI":"10.1186\/s12862-017-1097-6"},{"key":"B150","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.2.905"},{"key":"B151","doi-asserted-by":"publisher","DOI":"10.3390\/insects12080689"},{"key":"B152","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.18.9723"},{"key":"B153","doi-asserted-by":"crossref","unstructured":"Yang L, Borne F, Aardema ML, Zhen Y, Peng J, Wu M, Visconti R, Betz A, Roland BP, Talsma AD, Palladino MJ, Petschenka G, Andolfatto P. The path to \u201cfemmes fatales\u201d: the evolution of toxin resistance in predatory fireflies (Preprint).\n                      bioRxiv\n                      , 2023.","DOI":"10.2139\/ssrn.4464167"},{"key":"B154","doi-asserted-by":"publisher","DOI":"10.1093\/jmammal\/gyaa127"},{"key":"B155","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2011.1169"},{"key":"B156","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-68166-0_3"},{"key":"B157","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-68166-0_2"},{"key":"B158","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-39587-3"},{"key":"B159","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)41869-8"},{"key":"B160","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1919065117"},{"key":"B161","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2017.02.028"},{"key":"B162","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2016.2111"},{"key":"B163","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.2012.01751.x"},{"key":"B164","volume-title":"Osmotic Regulation in Aquatic Animals","author":"Krogh A","year":"1939"},{"key":"B165","first-page":"331","volume":"3","author":"Dean RB","year":"1941","journal-title":"Biol Symp"},{"key":"B166","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)72806-8"},{"key":"B167","volume":"45","author":"Schatzmann HJ","year":"1984","journal-title":"Curr Cont"},{"key":"B168","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1953.174.3.371"},{"key":"B169","doi-asserted-by":"publisher","DOI":"10.36866\/pn.96.32"},{"key":"B170","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00196.2017"},{"key":"B171","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1968.sp008467"},{"key":"B172","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1969.sp008704"},{"key":"B173","author":"Eschenhagen T","year":"2022","journal-title":"Goodman and Gilman's The Pharmacological Basis of Therapeutics"},{"key":"B174","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1973.0011"},{"key":"B175","first-page":"360","author":"Marshall PG","year":"1970","journal-title":"Rodd\u2019s Chemistry of Carbon Compounds"},{"key":"B176","doi-asserted-by":"publisher","DOI":"10.1002\/qsar.19880070307"},{"key":"B177","doi-asserted-by":"publisher","DOI":"10.1021\/jm800257s"},{"key":"B178","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2015.06.028"},{"key":"B179","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1380637"},{"key":"B180","doi-asserted-by":"publisher","DOI":"10.1124\/pr.108.000612"},{"key":"B181","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.17.6.923"},{"key":"B182","doi-asserted-by":"publisher","DOI":"10.1136\/vr.79.25.817"},{"key":"B183","doi-asserted-by":"publisher","DOI":"10.1136\/vr.102.6.119"},{"key":"B184","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483x(95)03296-r"},{"key":"B185","doi-asserted-by":"publisher","DOI":"10.3390\/toxins12080471"},{"key":"B186","doi-asserted-by":"publisher","DOI":"10.1007\/BF03161183"},{"key":"B187","doi-asserted-by":"publisher","DOI":"10.1038\/194480b0"},{"key":"B188","doi-asserted-by":"publisher","DOI":"10.1084\/jem.115.6.1173"},{"key":"B189","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106312"},{"key":"B190","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1974.2"},{"key":"B191","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106948"},{"key":"B192","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108206"},{"key":"B193","doi-asserted-by":"publisher","DOI":"10.1007\/BF01468860"},{"key":"B194","doi-asserted-by":"publisher","DOI":"10.1042\/cs0530329"},{"key":"B195","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1976.124"},{"key":"B196","doi-asserted-by":"publisher","DOI":"10.1042\/cs0530001"},{"key":"B197","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)32067-7"},{"key":"B198","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.47.29682"},{"key":"B199","first-page":"69","volume":"643","author":"Lingrel JB","year":"1998","journal-title":"Acta Physiol Scand Suppl"},{"key":"B200","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)39197-5"},{"key":"B201","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.24.14176"},{"key":"B202","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1222308110"},{"key":"B203","doi-asserted-by":"publisher","DOI":"10.1159\/000319588"},{"key":"B204","doi-asserted-by":"publisher","DOI":"10.1007\/s00239-016-9732-1"},{"key":"B205","doi-asserted-by":"publisher","DOI":"10.1007\/s00232-002-1041-5"},{"key":"B206","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpb.2016.01.007"},{"key":"B207","first-page":"339","volume":"4","author":"Canfield VA","year":"1992","journal-title":"New Biol"},{"key":"B208","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-12-08408.1995"},{"key":"B209","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.17.6.930"},{"key":"B210","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)91104-3"},{"key":"B211","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00098.2007"},{"key":"B212","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1994.275"},{"key":"B213","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1460369"},{"key":"B214","first-page":"377","volume":"44","author":"Goto A","year":"1992","journal-title":"Pharmacol Rev"},{"key":"B215","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1033.2002.02911.x"},{"key":"B216","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.23.5.632"},{"key":"B217","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.24.5.549"},{"key":"B218","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2014.01.038"},{"key":"B219","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/7.7.647"},{"key":"B220","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.114.03919"},{"key":"B221","doi-asserted-by":"publisher","DOI":"10.1002\/prp2.505"},{"key":"B222","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.86.2.694"},{"key":"B223","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00734.2009"},{"key":"B224","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00336.2011"},{"key":"B225","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/43.5.715"},{"key":"B226","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1650669"},{"key":"B227","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00648.2005"},{"key":"B228","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/714793"},{"key":"B229","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.17.6.936"},{"key":"B230","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/48.10.1720"},{"key":"B231","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.2.784"},{"key":"B232","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2011.04.019"},{"key":"B233","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2015.07.010"},{"key":"B234","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2015.07.011"},{"key":"B235","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2019.102156"},{"key":"B236","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad655.489"},{"key":"B237","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-68166-0_6"},{"key":"B238","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.54.2.268"},{"key":"B239","doi-asserted-by":"publisher","DOI":"10.1016\/s0039-128x(84)80012-4"},{"key":"B240","doi-asserted-by":"publisher","DOI":"10.1007\/BF02147562"},{"key":"B241","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2005.07.010"},{"key":"B242","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3182741599"},{"key":"B243","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000001042"},{"key":"B244","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.116.06599"},{"key":"B245","volume":"54","author":"Rogowski R","year":"2009","journal-title":"Hypertension"},{"key":"B246","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(63)91317-9"},{"key":"B247","first-page":"1433","volume":"47","author":"Rosenfeld EL","year":"1965","journal-title":"Bull Soc Chim Biol (Paris)"},{"key":"B248","first-page":"735","volume":"29","author":"Vidershain G","year":"1964","journal-title":"Biokhimiia"},{"key":"B249","first-page":"493","volume":"41","author":"Bourillon R","year":"1959","journal-title":"Bull Soc Chim Biol (Paris)"},{"key":"B250","doi-asserted-by":"publisher","DOI":"10.1042\/BCJ20160142"},{"key":"B251","doi-asserted-by":"publisher","DOI":"10.1038\/192871a0"},{"key":"B252","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2020.110687"},{"key":"B253","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.23.supplement_s21"},{"key":"B254","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.12.6654"},{"key":"B255","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)32669-8"},{"key":"B256","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.23.1_suppl.i102"},{"key":"B257","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.19.6.721"},{"key":"B258","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1995.1996"},{"key":"B259","doi-asserted-by":"publisher","DOI":"10.1080\/07435809609043784"},{"key":"B260","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-7061(97)90523-9"},{"key":"B261","doi-asserted-by":"publisher","DOI":"10.1007\/BF03347027"},{"key":"B262","doi-asserted-by":"crossref","DOI":"10.1097\/00004872-199212007-00002","volume":"10","author":"Manunta P","year":"1992","journal-title":"J Hypertens"},{"key":"B263","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(92)90881-7"},{"key":"B264","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.0000022659.17774.e4"},{"key":"B265","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00299.2003"},{"key":"B266","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvx214"},{"key":"B267","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0809253106"},{"key":"B268","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00322.2005"},{"key":"B269","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.17.8189"},{"key":"B270","doi-asserted-by":"publisher","DOI":"10.1124\/pr.108.000711"},{"key":"B271","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291x(92)91334-m"},{"key":"B272","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)92752-3"},{"key":"B273","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2003.022715"},{"key":"B274","doi-asserted-by":"publisher","DOI":"10.1007\/BF01900357"},{"key":"B275","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2018.05.020"},{"key":"B276","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2013.02.028"},{"key":"B277","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGENETICS.115.001217"},{"key":"B278","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(96)02257-x"},{"key":"B279","doi-asserted-by":"publisher","DOI":"10.3109\/10641969809053235"},{"key":"B280","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1958.tb01563.x"},{"key":"B281","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-198305000-00016"},{"key":"B282","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(63)90193-X"},{"key":"B283","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(64)90074-7"},{"key":"B284","first-page":"92","volume":"146","author":"Palmer RF","year":"1964","journal-title":"J Pharmacol Exp Ther"},{"key":"B285","first-page":"106","volume":"148","author":"McClane TK","year":"1965","journal-title":"J Pharmacol Exp Ther"},{"key":"B286","first-page":"581","volume":"154","author":"Oppelt WW","year":"1966","journal-title":"J Pharmacol Exp Ther"},{"key":"B287","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(66)90240-2"},{"key":"B288","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1972.sp009905"},{"key":"B289","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1976.sp011505"},{"key":"B290","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1978.sp012539"},{"key":"B291","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1979.tb13662.x"},{"key":"B292","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1983.sp014483"},{"key":"B293","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/BF01785527","volume":"65","author":"Lichtstein D","year":"1987","journal-title":"Klin Wochenschr"},{"key":"B294","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199816121-00015"},{"key":"B295","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.20028501"},{"key":"B296","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1987.tb13396.x"},{"key":"B297","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00593.2005"},{"key":"B298","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.1387"},{"key":"B299","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2009.10.021"},{"key":"B300","doi-asserted-by":"publisher","DOI":"10.1134\/S0006297916080083"},{"key":"B301","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1971.sp009317"},{"key":"B302","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.74.1.105"},{"key":"B303","first-page":"281","volume":"133","author":"Tuttle RS","year":"1961","journal-title":"J Pharmacol Exp Ther"},{"key":"B304","first-page":"142","volume":"135","author":"Tuttle RS","year":"1962","journal-title":"J Pharmacol Exp Ther"},{"key":"B305","first-page":"24","volume":"137","author":"Tuttle RS","year":"1962","journal-title":"J Pharmacol Exp Ther"},{"key":"B306","first-page":"480","volume":"242","author":"Klaus W","year":"1962","journal-title":"Arch Exp Path Pharmakol"},{"key":"B307","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196911272812203"},{"key":"B308","doi-asserted-by":"publisher","DOI":"10.1177\/1933719111424441"},{"key":"B309","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/5.9.600"},{"key":"B310","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.1998.274.1.F182"},{"key":"B311","doi-asserted-by":"publisher","DOI":"10.1042\/cs0870447"},{"key":"B312","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.23.supplement_s87"},{"key":"B313","doi-asserted-by":"publisher","DOI":"10.1578\/AM.48.2.2022.182"},{"key":"B314","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(74)90292-2"},{"key":"B315","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(83)90021-4"},{"key":"B316","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4838(83)90291-1"},{"key":"B317","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1997.tb52222.x"},{"key":"B318","first-page":"453","volume-title":"The Sodium Pump","author":"Hayashi Y","year":"1993"},{"key":"B319","first-page":"365","volume-title":"Na\/K-ATPase and related ATPases","author":"Taniguchi K","year":"2000"},{"key":"B320","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291x(69)90877-8"},{"key":"B321","first-page":"259","volume":"18","author":"Nandi DL","year":"1980","journal-title":"Mol Pharmacol"},{"key":"B322","first-page":"324","volume":"4","author":"Albers RW","year":"1968","journal-title":"Mol Pharmacol"},{"key":"B323","doi-asserted-by":"publisher","DOI":"10.1007\/s00232-021-00173-2"},{"key":"B324","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2362.2001.0310s2026.x"},{"key":"B325","first-page":"161","volume":"3","author":"Abarquez RF","year":"1967","journal-title":"Acta Med Philipp"},{"key":"B326","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.37.2.472"},{"key":"B327","first-page":"404,","volume":"20","author":"Manunta P","year":"1992","journal-title":"Hypertension"},{"key":"B328","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.34.4.733"},{"key":"B329","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2010.00701.x"},{"key":"B330","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00602.2006"},{"key":"B331","doi-asserted-by":"publisher","DOI":"10.1136\/vr.120.13.300"},{"key":"B332","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-200304000-00014"},{"key":"B333","doi-asserted-by":"publisher","DOI":"10.1124\/pr.57.4.6"},{"key":"B334","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00462.2012"},{"key":"B335","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M002950200"},{"key":"B336","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.111252"},{"key":"B337","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2000.279.2.H679"},{"key":"B338","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1979.236.4.H613"},{"key":"B339","doi-asserted-by":"publisher","DOI":"10.1590\/s0100-879x2001000800014"},{"key":"B340","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvs213"},{"key":"B341","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.29.1_supplement.984.3"},{"key":"B342","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-68166-0_10"},{"key":"B343","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.12.001"},{"key":"B344","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00158.2007"},{"key":"B345","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.964908"},{"key":"B346","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19092769"},{"key":"B347","doi-asserted-by":"publisher","DOI":"10.1124\/molpharm.120.000101"},{"key":"B348","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1975.sp011115"},{"key":"B349","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1993.265.5.C1443"},{"key":"B350","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01045.2009"},{"key":"B351","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2012.248336"},{"key":"B352","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1985.sp015672"},{"key":"B353","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(94)00735-p"},{"key":"B354","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00050.2005"},{"key":"B355","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathophys.2007.09.011"},{"key":"B356","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2015.08.011"},{"key":"B357","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.442137"},{"key":"B358","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2019.113679"},{"key":"B359","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)83247-1"},{"key":"B360","doi-asserted-by":"publisher","DOI":"10.1021\/bi3006913"},{"key":"B361","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110106"},{"key":"B362","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2018.07.002"},{"key":"B363","doi-asserted-by":"publisher","DOI":"10.1021\/bi0101751"},{"key":"B364","doi-asserted-by":"publisher","DOI":"10.1139\/cjpp-2020-0197"},{"key":"B365","doi-asserted-by":"publisher","DOI":"10.2174\/157340612799278531"},{"key":"B366","doi-asserted-by":"publisher","DOI":"10.3390\/life13071500"},{"key":"B367","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)38677-5"},{"key":"B368","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M009131200"},{"key":"B369","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2022.101865"},{"key":"B370","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvm150"},{"key":"B371","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.2004.04012.x"},{"key":"B372","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-008-0470-0"},{"key":"B373","doi-asserted-by":"publisher","DOI":"10.1134\/S0006297918020062"},{"key":"B374","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00008.2008"},{"key":"B375","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2010.01.013"},{"key":"B376","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22060990"},{"key":"B377","doi-asserted-by":"publisher","DOI":"10.1021\/bi4011804"},{"key":"B378","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.221315298"},{"key":"B379","doi-asserted-by":"publisher","DOI":"10.1111\/febs.12448"},{"key":"B380","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2014.08.006"},{"key":"B381","doi-asserted-by":"publisher","DOI":"10.1038\/ni1533"},{"key":"B382","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1721967115"},{"key":"B383","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e05-08-0735"},{"key":"B384","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M512240200"},{"key":"B385","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M609181200"},{"key":"B386","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.013821"},{"key":"B387","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00103.2015"},{"key":"B388","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M313239200"},{"key":"B389","doi-asserted-by":"publisher","DOI":"10.1021\/bi2009008"},{"key":"B390","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.721084"},{"key":"B391","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2019.102105"},{"key":"B392","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2012.01.015"},{"key":"B393","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084306"},{"key":"B394","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.03.071"},{"key":"B395","doi-asserted-by":"publisher","DOI":"10.1111\/apha.13059"},{"key":"B396","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.1996.0320"},{"key":"B397","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00555.2002"},{"key":"B398","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00130.2011"},{"key":"B399","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0600930103"},{"key":"B400","doi-asserted-by":"publisher","DOI":"10.1097\/FJC.0b013e3181ce5e14"},{"key":"B401","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0b013e318217a609"},{"key":"B402","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.08.070"},{"key":"B403","doi-asserted-by":"publisher","DOI":"10.1124\/mol.108.052597"},{"key":"B404","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2011.02.013"},{"key":"B405","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-2329com"},{"key":"B406","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2008.09.137"},{"key":"B407","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M410737200"},{"key":"B408","doi-asserted-by":"publisher","DOI":"10.1016\/s1097-2765(00)80349-4"},{"key":"B409","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.424663"},{"key":"B410","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00121.2011"},{"key":"B411","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00279.2007"},{"key":"B412","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00430.2015"},{"key":"B413","doi-asserted-by":"publisher","DOI":"10.1113\/JP272419"},{"key":"B414","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00083.2004"},{"key":"B415","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00625.2010"},{"key":"B416","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0108909"},{"key":"B417","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01216.2010"},{"key":"B418","doi-asserted-by":"publisher","DOI":"10.1161\/hyp.62.suppl_1.A400"},{"key":"B419","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-4756-6_31"},{"key":"B420","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.28.3.421"},{"key":"B421","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2011.255"},{"key":"B422","first-page":"315","volume":"15","author":"Delva P","year":"1989","journal-title":"Miner Electrolyte Metab"},{"key":"B423","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.30.4.886"},{"key":"B424","first-page":"17","volume":"2","author":"Masugi F","year":"1988","journal-title":"J Hum Hypertens"},{"key":"B425","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291x(86)90939-3"},{"key":"B426","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.23.1_suppl.i110"},{"key":"B427","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1994.266.4.H1357"},{"key":"B428","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.23.supplement_s61"},{"key":"B429","first-page":"595","volume":"113","author":"Yuan W","year":"2000","journal-title":"Chin Med J (Engl)"},{"key":"B430","doi-asserted-by":"publisher","DOI":"10.1590\/acb371102"},{"key":"B431","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2001.281.2.R635"},{"key":"B432","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.23.6.1087"},{"key":"B433","doi-asserted-by":"publisher","DOI":"10.1007\/s00360-009-0391-z"},{"key":"B434","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0704501"},{"key":"B435","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199405000-00008"},{"key":"B436","unstructured":"Kaplan NM, Victor RG. Kaplan's Clinical Hypertension (11th ed.). Philadelphia: Wolters Kluwer Health\/Lippincott Williams & Wilkins, 2015, p. 62\u2013146."},{"key":"B437","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.11.055"},{"key":"B438","first-page":"419","volume":"3","author":"Hasegawa T","year":"1987","journal-title":"J Clin Hypertens"},{"key":"B439","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1989.tb03594.x"},{"key":"B440","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000165623.72310.dd"},{"key":"B441","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-007-0041-3"},{"key":"B442","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008170.pub3"},{"key":"B443","doi-asserted-by":"publisher","DOI":"10.2147\/VHRM.S337640"},{"key":"B444","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-7061(96)00318-4"},{"key":"B445","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00256.2010"},{"key":"B446","doi-asserted-by":"publisher","DOI":"10.1161\/hyp.70.suppl_1.p331"},{"key":"B447","doi-asserted-by":"publisher","DOI":"10.1016\/0895-7061(95)00181-N"},{"key":"B448","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00518.2005"},{"key":"B449","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.12383"},{"key":"B450","doi-asserted-by":"publisher","DOI":"10.1038\/s41397-021-00214-y"},{"key":"B451","first-page":"1074","volume":"288","author":"Ferrari P","year":"1999","journal-title":"J Pharmacol Exp Ther"},{"key":"B452","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2008.224"},{"key":"B453","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1241739"},{"key":"B454","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-7061(99)00029-1"},{"key":"B455","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.18.145"},{"key":"B456","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.119.13818"},{"key":"B457","doi-asserted-by":"publisher","DOI":"10.1021\/jm970162e"},{"key":"B458","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2010.01.009"},{"key":"B459","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.104.065250"},{"key":"B460","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2008.05.005"},{"key":"B461","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00183.2008"},{"key":"B462","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00158.2011"},{"key":"B463","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2019.102151"},{"key":"B464","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2010.195"},{"key":"B465","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2013.01.012"},{"key":"B466","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2010.03.011"},{"key":"B467","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000250433.64202.78"},{"key":"B468","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000202594.82271.92"},{"key":"B469","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23094563"},{"key":"B470","doi-asserted-by":"publisher","DOI":"10.3109\/10641969809053240"},{"key":"B471","doi-asserted-by":"publisher","DOI":"10.3109\/10641963.2014.913604"},{"key":"B472","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-7061(98)00042-9"},{"key":"B473","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200402000-00025"},{"key":"B474","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.117.006704"},{"key":"B475","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199917080-00018"},{"key":"B476","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1272965"},{"key":"B477","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e328312c86a"},{"key":"B478","doi-asserted-by":"publisher","DOI":"10.1159\/000088461"},{"key":"B479","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000163153.27954.33"},{"key":"B480","doi-asserted-by":"publisher","DOI":"10.3109\/10641950802629709"},{"key":"B481","doi-asserted-by":"publisher","DOI":"10.3109\/10641955.2010.525275"},{"key":"B482","doi-asserted-by":"publisher","DOI":"10.1042\/CS20171499"},{"key":"B483","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.04.010"},{"key":"B484","doi-asserted-by":"publisher","DOI":"10.1042\/cs0740307"},{"key":"B485","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1989.tb00313.x"},{"key":"B486","doi-asserted-by":"publisher","DOI":"10.1096\/fj.14-252684"},{"key":"B487","doi-asserted-by":"publisher","DOI":"10.1126\/science.1111726"},{"key":"B488","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.853127"},{"key":"B489","doi-asserted-by":"publisher","DOI":"10.4415\/ANN_23_01_11"},{"key":"B490","doi-asserted-by":"publisher","DOI":"10.1016\/s0895-7061(97)00096-4"},{"key":"B491","doi-asserted-by":"publisher","DOI":"10.1161\/01.res.75.3.443"},{"key":"B492","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.295.6595.415-a"},{"key":"B493","first-page":"294","volume":"23","author":"Shilo L","year":"1987","journal-title":"Isr J Med Sci"},{"key":"B494","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.00282"},{"key":"B495","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00525.2006"},{"key":"B496","doi-asserted-by":"publisher","DOI":"10.1161\/01.res.84.5.562"},{"key":"B497","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvr106"},{"key":"B498","doi-asserted-by":"publisher","DOI":"10.1172\/JCI27702"},{"key":"B499","doi-asserted-by":"publisher","DOI":"10.1016\/s1050-1738(00)00057-8"},{"key":"B500","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.114.302293"},{"key":"B501","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00808.2020"},{"key":"B502","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfu200"},{"key":"B503","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00248.2013"},{"key":"B504","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22050729"},{"key":"B505","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12413"},{"key":"B506","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23031846"},{"key":"B507","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.65.1.84"},{"key":"B508","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22073462"},{"key":"B509","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.118.247692"},{"key":"B510","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2018.01.007"},{"key":"B511","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2005.04.082"},{"key":"B512","doi-asserted-by":"publisher","DOI":"10.1007\/s10517-023-05768-4"},{"key":"B513","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2010.04.013"},{"key":"B514","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2007.04.012"},{"key":"B515","doi-asserted-by":"publisher","DOI":"10.1159\/000447837"},{"key":"B516","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22126244"},{"key":"B517","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1992.tb05218.x"},{"key":"B518","doi-asserted-by":"publisher","DOI":"10.33594\/000000097"},{"key":"B519","doi-asserted-by":"publisher","DOI":"10.3390\/cimb45090475"},{"key":"B520","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8646787"},{"key":"B521","doi-asserted-by":"publisher","DOI":"10.1053\/j.ackd.2014.12.005"},{"key":"B522","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000059721.57219.C3"},{"key":"B523","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.96.5.1501"},{"key":"B524","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.824907"},{"key":"B525","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.117.309444"},{"key":"B526","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2010.12.008"},{"key":"B527","doi-asserted-by":"publisher","DOI":"10.1038\/sigtrans.2017.23"},{"key":"B528","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2010.178"},{"key":"B529","doi-asserted-by":"publisher","DOI":"10.1016\/j.cotox.2017.11.002"},{"key":"B530","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.908627"},{"key":"B531","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-05075-9"},{"key":"B532","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-017-1092-9"},{"key":"B533","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2022.108808"},{"key":"B534","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/171839"},{"key":"B535","doi-asserted-by":"publisher","DOI":"10.1111\/1440-1681.13783"},{"key":"B536","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/1094520"},{"key":"B537","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13453"},{"key":"B538","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2016.00010"},{"key":"B539","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-71027-5"},{"key":"B540","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00421.2022"},{"key":"B541","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-1109-8"},{"key":"B542","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-14243-5"},{"key":"B543","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-72879-7"},{"key":"B544","doi-asserted-by":"publisher","DOI":"10.1007\/s40011-021-01292-5"},{"key":"B545","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2023.109915"},{"key":"B546","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00693-16"},{"key":"B547","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00173.2018"},{"key":"B548","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02373-19"},{"key":"B549","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M305378200"},{"key":"B550","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.114.217133"},{"key":"B551","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17101728"},{"key":"B552","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.00995.x"},{"key":"B553","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00475.2007"},{"key":"B554","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008020174"},{"key":"B555","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2010.02.004"},{"key":"B556","doi-asserted-by":"publisher","DOI":"10.1016\/s0014-5793(99)00925-4"},{"key":"B557","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1997.273.5.C1458"},{"key":"B558","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00308.x"},{"key":"B559","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.2010.05364.x"},{"key":"B560","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.85.5.1912"},{"key":"B561","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.38.2.198"},{"key":"B562","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2010.03.001"},{"key":"B563","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32833ea821"},{"key":"B564","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-010-0161-z"},{"key":"B565","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200308000-00010"},{"key":"B566","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9440(10)64726-8"},{"key":"B567","doi-asserted-by":"publisher","DOI":"10.1007\/s00232-015-9832-7"},{"key":"B568","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2013.13"},{"key":"B569","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq772"},{"key":"B570","first-page":"684","volume":"81","author":"Romagnoli S","year":"2015","journal-title":"Minerva Anestesiol"},{"key":"B571","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.07830814"},{"key":"B572","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2018.10.012"},{"key":"B573","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.03.026"},{"key":"B574","doi-asserted-by":"publisher","DOI":"10.1159\/000294891"},{"key":"B575","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2019.04.021"},{"key":"B576","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2012.11.022"},{"key":"B577","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2020.144812"},{"key":"B578","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2018.12.003"},{"key":"B579","doi-asserted-by":"publisher","DOI":"10.1007\/s00232-021-00181-2"},{"key":"B580","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2000.00225.x"},{"key":"B581","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00018.x"},{"key":"B582","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007020252"},{"key":"B583","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2014.251"},{"key":"B584","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00462.2009"},{"key":"B585","doi-asserted-by":"publisher","DOI":"10.1007\/s43032-020-00280-w"},{"key":"B586","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0804150106"},{"key":"B587","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22083920"},{"key":"B588","doi-asserted-by":"publisher","DOI":"10.1042\/CS20220796"},{"key":"B589","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.525444"},{"key":"B590","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00454.2002"},{"key":"B591","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00487.2020"},{"key":"B592","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2018.08.008"},{"key":"B593","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31544-0"},{"key":"B594","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1996.0160"},{"key":"B595","doi-asserted-by":"publisher","DOI":"10.1016\/s0165-0327(98)00208-0"},{"key":"B596","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2009.03.032"},{"key":"B597","doi-asserted-by":"publisher","DOI":"10.1159\/000517343"},{"key":"B598","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci12111476"},{"key":"B599","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-015-4098-4"},{"key":"B600","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.306.6882.896"},{"key":"B601","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0000000000000104"},{"key":"B602","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0000000000000568"},{"key":"B603","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2021.112657"},{"key":"B604","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-5618.2003.00053.x"},{"key":"B605","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2019.09.016"},{"key":"B606","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-010-0455-0"},{"key":"B607","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2016.10.015"},{"key":"B608","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-019-0494-6"},{"key":"B609","doi-asserted-by":"publisher","DOI":"10.1124\/pr.111.005397"},{"key":"B610","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2011.05.007"},{"key":"B611","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4464-06.2007"},{"key":"B612","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-11-04667.2003"},{"key":"B613","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-183X.2011.00691.x"},{"key":"B614","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2016.00239"},{"key":"B615","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-3400986"},{"key":"B616","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.777607"},{"key":"B617","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2011.10.005"},{"key":"B618","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(14)70011-0"},{"key":"B619","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2017.12.009"},{"key":"B620","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000029413"},{"key":"B621","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000200927"},{"key":"B622","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182698d6c"},{"key":"B623","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0904817106"},{"key":"B624","doi-asserted-by":"publisher","DOI":"10.1007\/s10048-015-0461-1"},{"key":"B625","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00059.2021"},{"key":"B626","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15419"},{"key":"B627","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000036903.22461.39"},{"key":"B628","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2019.109430"},{"key":"B629","doi-asserted-by":"publisher","DOI":"10.3233\/VES-200788"},{"key":"B630","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003925"},{"key":"B631","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-017-2902-0"},{"key":"B632","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-018-1927-7"},{"key":"B633","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0218041"},{"key":"B634","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-019-09399-6"},{"key":"B635","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000908"},{"key":"B636","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181c0eaba"},{"key":"B637","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00445.x"},{"key":"B638","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(79)90996-6"},{"key":"B639","volume":"306","author":"Stenkvist B","year":"1982","journal-title":"N Engl J Med"},{"key":"B640","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-014-3058-8"},{"key":"B641","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.30520"},{"key":"B642","doi-asserted-by":"publisher","DOI":"10.1021\/cb500665r"},{"key":"B643","doi-asserted-by":"publisher","DOI":"10.1038\/cddiscovery.2017.9"},{"key":"B644","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.11.046"},{"key":"B645","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8274.CD-10-0020"},{"key":"B646","doi-asserted-by":"publisher","DOI":"10.1002\/pros.22733"},{"key":"B647","doi-asserted-by":"publisher","DOI":"10.1097\/JCMA.0000000000000288"},{"key":"B648","doi-asserted-by":"publisher","DOI":"10.1111\/and.14217"},{"key":"B649","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12287"},{"key":"B650","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2016.328"},{"key":"B651","doi-asserted-by":"publisher","DOI":"10.1002\/pds.4018"},{"key":"B652","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2017.01.004"},{"key":"B653","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-019-0122-z"},{"key":"B654","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12888-x"},{"key":"B655","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27196586"},{"key":"B656","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2022.106442"},{"key":"B657","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2682"},{"key":"B658","doi-asserted-by":"publisher","DOI":"10.1002\/tox.23130"},{"key":"B659","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2017.7070"},{"key":"B660","first-page":"5495","volume":"34","author":"Ninsontia C","year":"2014","journal-title":"Anticancer Res"},{"key":"B661","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-023-01317-8"},{"key":"B662","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.30762"},{"key":"B663","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-021-01841-2"},{"key":"B664","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000001879"},{"key":"B665","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2016.5426"},{"key":"B666","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.24157"},{"key":"B667","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2021-004297"},{"key":"B668","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000016969"},{"key":"B669","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8852261"},{"key":"B670","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2018.11.429"},{"key":"B671","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00548.2021"}],"container-title":["American Journal of Physiology-Cell Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpcell.00273.2023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T10:45:07Z","timestamp":1718621107000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpcell.00273.2023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,1]]},"references-count":671,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4,1]]}},"alternative-id":["10.1152\/ajpcell.00273.2023"],"URL":"https:\/\/doi.org\/10.1152\/ajpcell.00273.2023","relation":{},"ISSN":["0363-6143","1522-1563"],"issn-type":[{"value":"0363-6143","type":"print"},{"value":"1522-1563","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,1]]},"assertion":[{"value":"2023-06-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-22","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}