{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:07:03Z","timestamp":1790006823812,"version":"4.0.1"},"reference-count":44,"publisher":"American Physiological Society","issue":"4","funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["RGPIN-2020-06443"],"award-info":[{"award-number":["RGPIN-2020-06443"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["DGECR-2020-00136"],"award-info":[{"award-number":["DGECR-2020-00136"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000196","name":"Canada Foundation for Innovation","doi-asserted-by":"publisher","award":["38351"],"award-info":[{"award-number":["38351"]}],"id":[{"id":"10.13039\/501100000196","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ontario Research Fund","award":["38351"],"award-info":[{"award-number":["38351"]}]},{"name":"York University Muscle Health Research Centre Graduate Student Fellowship"},{"name":"Ontario Graduate Scholarship"}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Cell Physiology"],"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:p>\n                    We show that 4 wk of high-intensity interval training (HIIT) or low-intensity interval training (LIIT) via electrical stimulation (ES) improves fatigue resistance in mice via enhanced sarcoplasmic reticulum (SR) Ca\n                    <jats:sup>2+<\/jats:sup>\n                    transients and increased mitochondrial complex protein content. This study demonstrates the mechanisms by which fatigue resistance is improved with chronic electrical stimulation interval training exercise.\n                  <\/jats:p>","DOI":"10.1152\/ajpcell.00795.2025","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T20:33:31Z","timestamp":1788467611000},"page":"C1027-C1036","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["High-intensity interval training via electrical stimulation enhances endurance by preserving sarcoplasmic reticulum Ca\n                    <sup>2+<\/sup>\n                    transients in mouse skeletal muscle"],"prefix":"10.1152","volume":"331","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3841-7878","authenticated-orcid":false,"given":"Luke D.","family":"Flewwelling","sequence":"first","affiliation":[{"name":"York University","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7863-9041","authenticated-orcid":false,"given":"Masih","family":"Jafari","sequence":"additional","affiliation":[{"name":"York University","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahrzad","family":"Khajehzadehshoushtar","sequence":"additional","affiliation":[{"name":"York University","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1797-3880","authenticated-orcid":false,"given":"Takashi","family":"Yamada","sequence":"additional","affiliation":[{"name":"Hiroshima University","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5745-5888","authenticated-orcid":false,"given":"Christopher G. R.","family":"Perry","sequence":"additional","affiliation":[{"name":"York University","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3862-2967","authenticated-orcid":false,"given":"Arthur J.","family":"Cheng","sequence":"additional","affiliation":[{"name":"York University","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1113\/JP273196"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.112094"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1080\/026404197367335"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-018-0936-y"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2017.056"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00015.2007"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1991.261.2.C195"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00237.2005"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/s0005-2736(00)00195-4"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1996.80.1.261"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.75.1.382"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202101204R"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1111\/sms.70017"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.00810"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2000.279.1.R152"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1123\/ijsnem.22.4.276"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2007.142109"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1113\/EP091735"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.98.3.615"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)83641-4"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2025.102211"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1002\/1878-0261.12079"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1113\/JP287912"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2008.05.003"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2013.263251"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00530.2024"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-022-02846-2"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.201812152"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2008.163162"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1007\/s002329900063"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1007\/s004249900115"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1258\/ebm.2009.009165"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1007\/BF03165758"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1507176112"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.3233\/JND-230123"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00341.2014"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1023\/a:1019932730457"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2001.0393i.x"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-006-0381-8"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1991.tb16428.x"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000004522"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1186\/s40798-021-00344-4"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1123\/japa.2019-0111"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2008.12.029"}],"container-title":["American Journal of Physiology-Cell Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpcell.00795.2025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T15:43:56Z","timestamp":1790005436000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpcell.00795.2025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,1]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,10,1]]}},"alternative-id":["10.1152\/ajpcell.00795.2025"],"URL":"https:\/\/doi.org\/10.1152\/ajpcell.00795.2025","relation":{},"ISSN":["0363-6143","1522-1563"],"issn-type":[{"value":"0363-6143","type":"print"},{"value":"1522-1563","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,1]]},"assertion":[{"value":"2025-10-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-23","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}