{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T11:00:48Z","timestamp":1758279648754},"reference-count":0,"publisher":"American Physiological Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Cell Physiology"],"published-print":{"date-parts":[[1986,2,1]]},"abstract":"<jats:p> Effects of postnatal development, surgical cryptorchidism, and hypophysectomy on the activity of calmodulin and of a 32,000-molecular weight (32) calmodulin-binding protein (Ono et al., J. Biol. Chem. 259: 9011-9016, 1984) were examined in rat testis. In adult rats, approximately 95% of their activities distributed in seminiferous tubule preparation, and most of them were in the 105,000-g supernatant. Both activities were low early in the development, but the calmodulin activity increased between 25 and 45 days of age, and the 32 K calmodulin-binding protein activity increased between 35 and 45 days of age. In contrast, surgical cryptorchidism caused a rapid decline in their activities in the abdominal testis, whereas their activities in a scrotal testis did not decline. Hypophysectomy similarly resulted in a gradual decline in their activities. Replacement of follicle-stimulating hormone or testosterone for 7 days from 30 days after hypophysectomy did not quantitatively restore either the testes weight or the activities of the proteins. The results indicate a primary distribution of both proteins in mature germ cells. <\/jats:p>","DOI":"10.1152\/ajpcell.1986.250.2.c299","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T09:08:22Z","timestamp":1514106502000},"page":"C299-C305","source":"Crossref","is-referenced-by-count":8,"title":["Alterations in activities of calmodulin and heat-stable calmodulin-binding protein in rat testis"],"prefix":"10.1152","volume":"250","author":[{"given":"Y.","family":"Koide","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Ono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ishinami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["American Journal of Physiology-Cell Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpcell.1986.250.2.C299","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T19:52:48Z","timestamp":1718653968000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpcell.1986.250.2.C299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1986,2,1]]}},"alternative-id":["10.1152\/ajpcell.1986.250.2.C299"],"URL":"https:\/\/doi.org\/10.1152\/ajpcell.1986.250.2.c299","relation":{},"ISSN":["0363-6143","1522-1563"],"issn-type":[{"value":"0363-6143","type":"print"},{"value":"1522-1563","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,2,1]]}}}