{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T22:16:58Z","timestamp":1767651418051},"reference-count":0,"publisher":"American Physiological Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Cell Physiology"],"published-print":{"date-parts":[[1993,2,1]]},"abstract":"<jats:p> In young rats fed a Mg(2+)-deficient diet for 3 wk, Mg2+ and K+ contents in soleus and extensor digitorum longus muscles were significantly reduced and closely correlated. In isolated soleus muscles, Mg2+ depletion induced an even more pronounced loss of K+, and Mg2+ and K+ contents were correlated over a wide range (r = 0.95, P &lt; 0.001). Extracellular Mg2+ (0-1.2 mM) caused no change in total or ouabain-suppressible 86Rb influx. After long-term incubation in Ca(2+)-Mg(2+)-free buffer with EDTA and EGTA, cellular Mg2+ and K+ contents were reduced by 35 and 15%, respectively, without any reduction in ATP and total or ouabain-suppressible 86Rb influx. In Mg(2+)-depleted muscles 42K efflux was increased by up to 42%, and repletion with Mg2+ produced a graded decrease. We conclude that Mg2+ and K+ contents are closely correlated in muscles Mg2+ depleted in vivo or in vitro and that neither extracellular nor moderate intracellular Mg2+ depletion affects total or Na(+)-K+ pump-mediated K+ influx. The reduced K+ content may rather be related to increased K+ efflux from the muscles. <\/jats:p>","DOI":"10.1152\/ajpcell.1993.264.2.c457","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T14:06:14Z","timestamp":1514124374000},"page":"C457-C463","source":"Crossref","is-referenced-by-count":31,"title":["Correlation between magnesium and potassium contents in muscle: role of Na(+)-K+ pump"],"prefix":"10.1152","volume":"264","author":[{"given":"I.","family":"Dorup","sequence":"first","affiliation":[{"name":"Institute of Physiology, University of Aarhus, Denmark."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Clausen","sequence":"additional","affiliation":[{"name":"Institute of Physiology, University of Aarhus, Denmark."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["American Journal of Physiology-Cell Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpcell.1993.264.2.C457","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T19:43:00Z","timestamp":1718653380000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpcell.1993.264.2.C457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1993,2,1]]}},"alternative-id":["10.1152\/ajpcell.1993.264.2.C457"],"URL":"https:\/\/doi.org\/10.1152\/ajpcell.1993.264.2.c457","relation":{},"ISSN":["0363-6143","1522-1563"],"issn-type":[{"value":"0363-6143","type":"print"},{"value":"1522-1563","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,2,1]]}}}