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In this cross-sectional study we compared resting energy expenditure (REE) and energy intake in 30 HAART-treated patients with lipodystrophy (HAART+LD+) with 13 HAART-treated patients without lipodystrophy (HAART+LD\u2212). REE was measured using indirect calorimetry, and energy intake was recorded as a 3-day diary of food intake. REE (5,180 \u00b1 160 vs. 4,260 \u00b1 150 J\/min, P &lt; 0.01) and also REE expressed per fat-free mass (86 \u00b1 1 vs. 78 \u00b1 2 J\u00b7kg fat-free mass<jats:sup>\u22121<\/jats:sup>\u00b7min<jats:sup>\u22121<\/jats:sup>, P &lt; 0.01) were significantly higher in the HAART+LD+ than the HAART+LD\u2212 group. Rate of lipid oxidation was significantly higher in the HAART+LD+ than the HAART+LD\u2212 group. Total energy and fat intakes were significantly increased in the HAART+LD+ compared with the HAART+LD\u2212 group. These results imply that HAART-associated lipodystrophy is associated with increased REE and lipid oxidation and with increased caloric and fat intake.<\/jats:p>","DOI":"10.1152\/ajpendo.00219.2006","type":"journal-article","created":{"date-parts":[[2006,10,25]],"date-time":"2006-10-25T03:11:39Z","timestamp":1161745899000},"page":"E687-E692","source":"Crossref","is-referenced-by-count":27,"title":["Increased resting energy expenditure, fat oxidation, and food intake in patients with highly active antiretroviral therapy-associated 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