{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:46:40Z","timestamp":1782841600711,"version":"3.54.5"},"reference-count":18,"publisher":"American Physiological Society","issue":"1","funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["25SFRNPCKMS1469680"],"award-info":[{"award-number":["25SFRNPCKMS1469680"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["AHA 1362572"],"award-info":[{"award-number":["AHA 1362572"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["AHA1192508"],"award-info":[{"award-number":["AHA1192508"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"HHS | NIH | National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R00HL146948"],"award-info":[{"award-number":["R00HL146948"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017540","name":"HHS | NIH | NHLBI | Division of Intramural Research","doi-asserted-by":"publisher","award":["R01HL169576"],"award-info":[{"award-number":["R01HL169576"]}],"id":[{"id":"10.13039\/100017540","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["AHA 1196923"],"award-info":[{"award-number":["AHA 1196923"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Endocrinology and Metabolism"],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:p>Black patients in United States are at a discrepant high risk for preeclampsia, via mechanisms unknown. We found that White patients with preeclampsia had significantly higher changes in gene and placental morphological expressions compared with healthy pregnancy than observed in Black patients with preeclampsia. These data indicate that placental damage in preeclampsia in our cohort was less evident in Black patients with preeclampsia compared with White patients with preeclampsia and that nonplacental mechanisms for disease may be predominate in Black patients with preeclampsia.<\/jats:p>","DOI":"10.1152\/ajpendo.00476.2025","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:31:06Z","timestamp":1780403466000},"page":"E87-E97","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Placental discrepancies between Black and White patients with preeclampsia in a southeastern US cohort"],"prefix":"10.1152","volume":"331","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4166-1821","authenticated-orcid":false,"given":"Madison","family":"Ives","sequence":"first","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gibson","family":"Cooper","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8828-0488","authenticated-orcid":false,"given":"Cayman","family":"Bickerstaff","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Elgazzaz","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra","family":"Sam","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1416-1003","authenticated-orcid":false,"given":"Amalia","family":"Brawley","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safia","family":"Ogbi","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3692-5905","authenticated-orcid":false,"given":"Elisabeth","family":"Mellott","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8134-0645","authenticated-orcid":false,"given":"Desmond","family":"Moronge","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Stokes","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Hitchings","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Valesquez Zarate","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sravankumar","family":"Kavuri","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6942-2074","authenticated-orcid":false,"given":"Padmashree C.","family":"Woodham","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Maher","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3362-412X","authenticated-orcid":false,"given":"Jessica L.","family":"Faulkner","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University","place":["United States"]},{"name":"Medical College of Georgia at Augusta University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1161\/RES.0000000000000315"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.124.321676"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003891"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/OGX.0000000000000747"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.07.038"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s40615-019-00619-3"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12758"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1080\/15513815.2019.1710880"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1159\/000477933"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2010.01.040"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2023.10.008"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2015-0225-CC"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.34067\/KID.0000102019"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2025.2466210"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1007\/s40615-019-00580-1"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.121.18451"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.3109\/10641955.2014.925564"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21532"}],"container-title":["American Journal of Physiology-Endocrinology and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpendo.00476.2025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T17:06:36Z","timestamp":1782839196000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpendo.00476.2025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7,1]]}},"alternative-id":["10.1152\/ajpendo.00476.2025"],"URL":"https:\/\/doi.org\/10.1152\/ajpendo.00476.2025","relation":{},"ISSN":["0193-1849","1522-1555"],"issn-type":[{"value":"0193-1849","type":"print"},{"value":"1522-1555","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,1]]},"assertion":[{"value":"2025-10-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-01","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}