{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:16:23Z","timestamp":1785417383568,"version":"3.56.0"},"reference-count":46,"publisher":"American Physiological Society","issue":"3","funder":[{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["U01TR002953"],"award-info":[{"award-number":["U01TR002953"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["T32OD011130"],"award-info":[{"award-number":["T32OD011130"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["K01OD028207"],"award-info":[{"award-number":["K01OD028207"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R01HD095876"],"award-info":[{"award-number":["R01HD095876"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"U.S. Department of Agriculture","doi-asserted-by":"publisher","award":["NIFA 2019-67017-29372"],"award-info":[{"award-number":["NIFA 2019-67017-29372"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["P30DK034987"],"award-info":[{"award-number":["P30DK034987"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011490","name":"NCSU | College of Veterinary Medicine, North Carolina State University","doi-asserted-by":"publisher","award":["EFIG2202-01"],"award-info":[{"award-number":["EFIG2202-01"]}],"id":[{"id":"10.13039\/100011490","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Gastrointestinal and Liver Physiology"],"published-print":{"date-parts":[[2025,3,1]]},"abstract":"<jats:p>These studies validate an approach to identify and predict upstream regulation of restituting epithelium in a unique pig intestinal ischemic injury model. Identification of potential molecular mediators of restitution, such as CSF-1, will inform the development of targeted therapeutic interventions for the medical management of patients with ischemia-mediated intestinal injury.<\/jats:p>","DOI":"10.1152\/ajpgi.00194.2024","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T11:01:17Z","timestamp":1737716477000},"page":"G182-G196","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestine"],"prefix":"10.1152","volume":"328","author":[{"given":"Elizabeth C.","family":"Rose","sequence":"first","affiliation":[{"name":"North Carolina State University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy M.","family":"Simon","sequence":"additional","affiliation":[{"name":"University of North Carolina at Chapel Hill","place":["United States"]},{"name":"University of North Carolina at Chapel Hill","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismael","family":"Gomez-Martinez","sequence":"additional","affiliation":[{"name":"University of North Carolina at Chapel Hill","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2746-1224","authenticated-orcid":false,"given":"Scott T.","family":"Magness","sequence":"additional","affiliation":[{"name":"University of North Carolina at Chapel Hill","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4965-2096","authenticated-orcid":false,"given":"Jack","family":"Odle","sequence":"additional","affiliation":[{"name":"North Carolina State University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony T.","family":"Blikslager","sequence":"additional","affiliation":[{"name":"North Carolina State University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4450-0536","authenticated-orcid":false,"given":"Amanda L.","family":"Ziegler","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04tj63d06","id-type":"ROR","asserted-by":"publisher"}],"name":"North Carolina State University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20499"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115741"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1007\/BF01213309"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3945\/jn.111.150995"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00380.2005"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2016.09.003"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00112.2013"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1017\/S0954422416000020"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1177\/0300985811402846"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-animal-020518-115142"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0200674"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00216.2022"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2022.02.007"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1093\/jas\/skac318"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-018-0105-4"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(93)90412-6"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2017.02.011"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2019.01389"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-015-0862-3"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1009290"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.24956.2"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3192"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-005-0067-z"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2007.00359.x"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.12.029"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.440909"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.09.059"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00165.2021"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt703"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i42.9300"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(93)90136-z"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-3260com"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1159\/000188076"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1089\/jir.2013.0044"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aaz6821"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1126\/science.1223821"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0000000000000333"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2019.02.006"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00012.2006"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-27409-x"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1172\/JCI39087"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.03.004"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.2217\/fon.09.103"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056951"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.scr.2012.12.001"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/s41385-022-00563-2"}],"container-title":["American Journal of Physiology-Gastrointestinal and Liver Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpgi.00194.2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T10:48:35Z","timestamp":1744627715000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpgi.00194.2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,1]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3,1]]}},"alternative-id":["10.1152\/ajpgi.00194.2024"],"URL":"https:\/\/doi.org\/10.1152\/ajpgi.00194.2024","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.06.28.601271","asserted-by":"object"}]},"ISSN":["0193-1857","1522-1547"],"issn-type":[{"value":"0193-1857","type":"print"},{"value":"1522-1547","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,1]]},"assertion":[{"value":"2024-07-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-05","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}