{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T15:48:43Z","timestamp":1780760923902,"version":"3.54.1"},"reference-count":54,"publisher":"American Physiological Society","issue":"5","funder":[{"name":"Sunshine Charitable Foundation"},{"DOI":"10.13039\/100008477","name":"Buckeye Career Center Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008477","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011860","name":"Campaign Urging Research for Eosinophilic Disease","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011860","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AI045898"],"award-info":[{"award-number":["R01 AI045898"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AI124355"],"award-info":[{"award-number":["R01 AI124355"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["U19 AI070235"],"award-info":[{"award-number":["U19 AI070235"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["P30 DK078392"],"award-info":[{"award-number":["P30 DK078392"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Gastrointestinal and Liver Physiology"],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:p> The interaction between amniotic fluid and the esophageal epithelium during pregnancy modifies esophageal epithelial differentiation and subsequent responsiveness to inflammatory stimuli, including interleukin 13 (IL-13). This interaction may predispose individuals to inflammatory conditions of the esophagus, such as eosinophilic esophagitis (EoE), in later stages of life. <\/jats:p>","DOI":"10.1152\/ajpgi.00197.2024","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T13:08:55Z","timestamp":1724764135000},"page":"G629-G639","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Amniotic fluid modifies esophageal epithelium differentiation and inflammatory responses"],"prefix":"10.1152","volume":"327","author":[{"given":"Mark","family":"Rochman","sequence":"first","affiliation":[{"name":"Division of Allergy and Immunology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea M.","family":"Klinger","sequence":"additional","affiliation":[{"name":"Division of Allergy and Immunology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie M.","family":"Caldwell","sequence":"additional","affiliation":[{"name":"Division of Allergy and Immunology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoel","family":"Sadovsky","sequence":"additional","affiliation":[{"name":"Magee-Womens Research Institute, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States"},{"name":"Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9790-6332","authenticated-orcid":false,"given":"Marc E.","family":"Rothenberg","sequence":"additional","affiliation":[{"name":"Division of Allergy and Immunology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-016-2713-y"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1071008"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(86)90189-7"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211290"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-44125-3"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2019.00497"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.08.040"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1093\/dote\/doaa074"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2021.109003"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2014.04.002"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2012.11.002"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2010.00626.x"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.06.065"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.07.021"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.10.017"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.86355"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318290d15a"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2022-327166"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2017.12.013"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp427"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac1000"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2023.06.005"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2015.00318"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-28157-3"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/3.5.517"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/0028-2243(94)90162-7"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2014.02.018"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2021.103440"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.10.024"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.04.015"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2010.12.004"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.07.010"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2023.4609"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1186\/s40659-015-0029-4"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-020-0255-7"},{"key":"B36","first-page":"2330","volume":"19","author":"Davari M","year":"2013","journal-title":"Mol Vis"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.115.9.1783"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2011.437"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1038\/gene.2014.27"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2018.01.011"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2018.08.008"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1242\/dev.178855"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29747-x"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)78805-X"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.106211"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)03265-7"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1111\/pai.12608"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-10580-y"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.3390\/cells12232745"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.36849\/JDD.7308"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3033"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.10.018"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abp9940"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2023.07.041"}],"container-title":["American Journal of Physiology-Gastrointestinal and Liver Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpgi.00197.2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T13:55:38Z","timestamp":1728568538000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpgi.00197.2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,1]]},"references-count":54,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,11,1]]}},"alternative-id":["10.1152\/ajpgi.00197.2024"],"URL":"https:\/\/doi.org\/10.1152\/ajpgi.00197.2024","relation":{},"ISSN":["0193-1857","1522-1547"],"issn-type":[{"value":"0193-1857","type":"print"},{"value":"1522-1547","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,1]]},"assertion":[{"value":"2024-07-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-15","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}