{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T07:04:21Z","timestamp":1648883061335},"reference-count":0,"publisher":"American Physiological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Gastrointestinal and Liver Physiology"],"published-print":{"date-parts":[[1986,4,1]]},"abstract":"<jats:p> Thiocyanate (SCN) produced a rapid inhibition of acid secretion and a concurrent rapid increase in the transmucosal potential difference (PD) and resistance. After inhibition, resistance rapidly peaked and then decreased. In contrast, omeprazole produced a slow inhibition of secretion and a slow increase in PD and resistance. The peak increase in resistance with SCN was significantly greater than the steady-state increases for both SCN and omeprazole. All increases were significant. The increases in PD and resistance are greater at high H+ rates than at low H+ rates. We postulate that the peak SCN increase in resistance is due to the increase in resistance of the secretory membrane, which is followed by a decrease in resistance of the nutrient membrane. On this basis the omeprazole increase in resistance that occurs concurrently with the slow decrease in the H+ rate is a result of a concurrent change of the resistances of the two opposing membranes. <\/jats:p>","DOI":"10.1152\/ajpgi.1986.250.4.g511","type":"journal-article","created":{"date-parts":[[2017,12,23]],"date-time":"2017-12-23T21:03:22Z","timestamp":1514063002000},"page":"G511-G517","source":"Crossref","is-referenced-by-count":1,"title":["Effects of NaSCN and omeprazole on resistance and potential of fundus of Rana pipiens"],"prefix":"10.1152","volume":"250","author":[{"given":"W. S.","family":"Rehm","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Carrasquer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["American Journal of Physiology-Gastrointestinal and Liver Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/ajpgi.1986.250.4.G511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T21:48:02Z","timestamp":1567979282000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/ajpgi.1986.250.4.G511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1986,4,1]]}},"alternative-id":["10.1152\/ajpgi.1986.250.4.G511"],"URL":"https:\/\/doi.org\/10.1152\/ajpgi.1986.250.4.g511","relation":{},"ISSN":["0193-1857","1522-1547"],"issn-type":[{"value":"0193-1857","type":"print"},{"value":"1522-1547","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,4,1]]}}}