{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:13:25Z","timestamp":1793330005616,"version":"4.5.0"},"reference-count":29,"publisher":"American Physiological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Gastrointestinal and Liver Physiology"],"published-print":{"date-parts":[[1998,4]]},"DOI":"10.1152\/ajpgi.1998.274.4.g669","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T03:49:07Z","timestamp":1514087347000},"page":"G669-G676","source":"Crossref","is-referenced-by-count":57,"title":["Estrogen increases sensitivity of hepatic Kupffer cells to endotoxin"],"prefix":"10.1152","volume":"274","author":[{"given":"Kenichi","family":"Ikejima","sequence":"first","affiliation":[{"name":"Laboratory of Hepatobiology and Toxicology, Department of Pharmacology,"},{"name":"Division of Digestive Diseases and Nutrition, Department of Medicine, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyuki","family":"Enomoto","sequence":"additional","affiliation":[{"name":"Laboratory of Hepatobiology and Toxicology, Department of Pharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Iimuro","sequence":"additional","affiliation":[{"name":"Laboratory of Hepatobiology and Toxicology, Department of Pharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Ikejima","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases and Nutrition, Department of Medicine, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawn","family":"Fang","sequence":"additional","affiliation":[{"name":"Laboratory of Hepatobiology and Toxicology, Department of Pharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Xu","sequence":"additional","affiliation":[{"name":"Laboratory of Hepatobiology and Toxicology, Department of Pharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald T.","family":"Forman","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7365"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Brenner","sequence":"additional","affiliation":[{"name":"Division of Digestive Diseases and Nutrition, Department of Medicine, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald G.","family":"Thurman","sequence":"additional","affiliation":[{"name":"Laboratory of Hepatobiology and Toxicology, Department of Pharmacology,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.4049\/jimmunol.29.3.255","volume":"29","author":"Apitz K.","year":"1935","journal-title":"J. Immunol."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00591a005"},{"key":"B3","first-page":"820","volume":"81","author":"Cutolo M.","year":"1996","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1126\/science.8456300"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1990.tb19222.x"},{"key":"B6","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.4049\/jimmunol.141.7.2407","volume":"141","author":"Ding A. H.","year":"1988","journal-title":"J. Immunol."},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830181018"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(82)90118-X"},{"key":"B9","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1016\/S0021-9258(19)83641-4","volume":"260","author":"Grynkiewicz G.","year":"1985","journal-title":"J. Biol. Chem."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.1990.tb02820.x"},{"key":"B11","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0026-895X(25)08927-8","volume":"41","author":"Hijioka T.","year":"1992","journal-title":"Mol. Pharmacol."},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510240217"},{"key":"B13","doi-asserted-by":"crossref","first-page":"328A","DOI":"10.1016\/S0168-8278(96)80013-4","volume":"24","author":"Ikejima K.","year":"1996","journal-title":"Hepatology"},{"issue":"34","key":"B14","first-page":"G97","volume":"271","author":"Ikejima K.","year":"1996","journal-title":"Am. J. Physiol."},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/0952-3278(92)90241-A"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.9.3629"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(90)91565-A"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1084\/jem.170.3.827"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-999718"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840010516"},{"key":"B22","first-page":"501","volume":"71","author":"Nolan J. P.","year":"1968","journal-title":"J. Lab. Clin. Med."},{"key":"B24","first-page":"5398","volume":"5","author":"Savier E.","year":"1992","journal-title":"Transpl. Int."},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1126\/science.3764421"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1038\/330662a0"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32330-4"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(62)90034-0"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1995.tb14955.x"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1084\/jem.177.6.1779"},{"key":"B32","first-page":"18","volume":"86","author":"Zuckerman S. H.","year":"1995","journal-title":"Immunology"}],"container-title":["American Journal of Physiology-Gastrointestinal and Liver Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.physiology.org\/doi\/pdf\/10.1152\/ajpgi.1998.274.4.G669","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T01:03:00Z","timestamp":1751158980000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.physiology.org\/doi\/10.1152\/ajpgi.1998.274.4.G669"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,4]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1998,4]]}},"alternative-id":["10.1152\/ajpgi.1998.274.4.G669"],"URL":"https:\/\/doi.org\/10.1152\/ajpgi.1998.274.4.g669","relation":{},"ISSN":["0193-1857","1522-1547"],"issn-type":[{"value":"0193-1857","type":"print"},{"value":"1522-1547","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,4]]}}}