{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:48:11Z","timestamp":1792799291484,"version":"4.5.0"},"reference-count":61,"publisher":"American Physiological Society","issue":"4","funder":[{"name":"Minist\u00e8re de l'\u00c9ducation, du Loisir et du Sport du Qu\u00e9bec","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"https:\/\/ror.org\/00bhh3q35","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Foundation of the Institut universitaire de cardiologie et de pneumologie de Qu\u00e9bec","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"https:\/\/ror.org\/03gf7z214","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Instituts de recherche en sant\u00e9 du Canada","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"https:\/\/ror.org\/01gavpb45","id-type":"ROR","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000156","name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","doi-asserted-by":"publisher","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/501100000156","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Soci\u00e9t\u00e9 qu\u00e9b\u00e9coise d'hypertension art\u00e9rielle","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"https:\/\/ror.org\/058jpya11","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"published-print":{"date-parts":[[2019,10,1]]},"abstract":"<jats:p>\n                    High-intensity interval training (HIIT) improves physical performance of endurance athletes, although studies examining its cardiovascular effects are sparse. We evaluated the impact of HIIT on blood pressure, heart rate, and cardiac cavities\u2019 size and function in endurance-trained adults. Seventeen endurance-trained men underwent 24-h ambulatory blood pressure monitoring and Doppler echocardiography at baseline and after 6 wk of HIIT. Participants were divided into 2 groups [85% maximal aerobic power (HIIT\n                    <jats:sub>85<\/jats:sub>\n                    ), n = 8 and 115% maximal aerobic power (HIIT\n                    <jats:sub>115<\/jats:sub>\n                    ), n = 9] to compare the impact of different HIIT intensities. Ambulatory blood pressure monitoring and cardiac chambers\u2019 size and function were similar between groups at baseline. HIIT reduced heart rate (55\u2009\u00b1\u20098 vs. 51\u2009\u00b1\u20097 beats\/min; P = 0.003), systolic blood pressure (121\u2009\u00b1\u200911 vs. 118\u2009\u00b1\u20099 mmHg; P = 0.01), mean arterial pressure (90\u2009\u00b1\u20098 vs. 89\u2009\u00b1\u20096 mmHg; P = 0.03), and pulse pressure (52\u2009\u00b1\u20096 vs. 49\u2009\u00b1\u20095 mmHg; P = 0.01) irrespective of training intensity. Left atrium volumes increased after HIIT (maximal: 50\u2009\u00b1\u200914 vs. 54\u2009\u00b1\u200914 mL; P = 0.02; minimal: 15\u2009\u00b1\u20095 vs. 20\u2009\u00b1\u20098 mL; P = 0.01) in both groups. Right ventricle global longitudinal strain lowered after training in the HIIT\n                    <jats:sub>85<\/jats:sub>\n                    group only (20\u2009\u00b1\u20094 vs. 17\u2009\u00b1\u20093%, P = 0.04). In endurance-trained men, 6 wk of HIIT reduced systolic blood pressure and mean arterial pressure and increased left atrium volumes irrespective of training intensity, whereas submaximal HIIT deteriorated right ventricle systolic function.\n                  <\/jats:p>\n                  <jats:p>NEW &amp; NOTEWORTHY The novel findings of this study are that 6 wk of high-intensity interval training increases left atrial volumes irrespective of training intensity (85 or 115% maximal aerobic power), whereas the submaximal training decreases right ventricular systolic function in endurance-trained men. These results may help identify the exercise threshold for potential toxicity of intense exercise training for at-risk individuals and ideal exercise training regimens conferring optimal cardiovascular protection and adapted endurance training for athletes.<\/jats:p>","DOI":"10.1152\/ajpheart.00196.2019","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T11:49:31Z","timestamp":1564141771000},"page":"H685-H694","source":"Crossref","is-referenced-by-count":22,"title":["Cardiac remodeling after six weeks of high-intensity interval training to exhaustion in endurance-trained men"],"prefix":"10.1152","volume":"317","author":[{"given":"Ha\u00effa","family":"Mahjoub","sequence":"first","affiliation":[{"name":"Department of Medicine, Universit\u00e9 Laval, Qu\u00e9bec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Le Blanc","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, Faculty of 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