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The chronobiological and chronomic interpretation of ambulatory blood pressure monitoring (C-ABPM) records in the light of time-specified reference values derived from healthy peers matched by sex and age identify vascular variability anomalies (VVAs) for an assessment of cardio-, cerebro-, and renovascular disease risk. Even within the conventionally accepted normal range, VVAs have been associated with a statistically significant increase in risk. Long-term C-ABPM records help to \u201cknow ourselves,\u201d serving for relief of psychological and other strain once transient VVAs are linked to the source of a load, prompting adjustment of one's lifestyle for strain reduction. Persistent circadian VVAs can be treated, sometimes by no more than a change in timing of the daily administration of antihypertensive medication. Circadian VVA assessment is an emergency worldwide, prompted in the United States by 1,000 deaths per day every day from problems related to blood pressure. While some heads of state met under United Nation and World Health Organization sponsorship to declare that noncommunicable diseases are a slow-motion disaster, a resolution has been drafted to propose C-ABPM as an added tool complementing purely physical environmental monitoring to contribute also to the understanding of social and natural as well as personal cataclysms.<\/jats:p>","DOI":"10.1152\/ajpheart.00212.2013","type":"journal-article","created":{"date-parts":[[2013,5,25]],"date-time":"2013-05-25T03:48:32Z","timestamp":1369453712000},"page":"H279-H294","source":"Crossref","is-referenced-by-count":32,"title":["Diagnosing vascular variability anomalies, not only MESOR-hypertension"],"prefix":"10.1152","volume":"305","author":[{"given":"Franz","family":"Halberg","sequence":"first","affiliation":[{"name":"University of Minnesota Academic Health Center, Minneapolis, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Powell","sequence":"additional","affiliation":[{"name":"University of Minnesota Academic Health Center, Minneapolis, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuniaki","family":"Otsuka","sequence":"additional","affiliation":[{"name":"Tokyo Women's Medical University, Medical Center East, Tokyo, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Tokyo Women's Medical University, Medical Center East, Tokyo, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry A.","family":"Beaty","sequence":"additional","affiliation":[{"name":"University of Minnesota Academic Health Center, Minneapolis, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Rosch","sequence":"additional","affiliation":[{"name":"American Institute of Stress, Yonkers, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy","family":"Czaplicki","sequence":"additional","affiliation":[{"name":"Institute of Pharmacology and Structural Biology, Centre national de la recherche scientifique-Unit\u00e9s propres de recherche 5089, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dewayne","family":"Hillman","sequence":"additional","affiliation":[{"name":"University of Minnesota Academic Health Center, Minneapolis, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Othild","family":"Schwartzkopff","sequence":"additional","affiliation":[{"name":"University of Minnesota Academic Health Center, Minneapolis, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germaine","family":"Cornelissen","sequence":"additional","affiliation":[{"name":"University of Minnesota Academic Health Center, Minneapolis, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","first-page":"20","volume-title":"Minnesota Physician","author":"Baecher CJ","year":"2013"},{"key":"B2","doi-asserted-by":"crossref","DOI":"10.2979\/3866.0","volume-title":"Science and Russian Culture in an Age of Revolutions: V. 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