{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T18:54:36Z","timestamp":1781808876114,"version":"3.54.5"},"reference-count":41,"publisher":"American Physiological Society","issue":"1","funder":[{"DOI":"10.13039\/501100020140","name":"Amsterdam Neuroscience","doi-asserted-by":"publisher","award":["813294"],"award-info":[{"award-number":["813294"]}],"id":[{"id":"10.13039\/501100020140","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019741","name":"AUMC | Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers","doi-asserted-by":"publisher","award":["Equipment call 2021 and 2023"],"award-info":[{"award-number":["Equipment call 2021 and 2023"]}],"id":[{"id":"10.13039\/100019741","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002996","name":"Hartstichting","doi-asserted-by":"publisher","award":["03-006-2021-T019"],"award-info":[{"award-number":["03-006-2021-T019"]}],"id":[{"id":"10.13039\/501100002996","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["VENI 09150162410015"],"award-info":[{"award-number":["VENI 09150162410015"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Dutch Heart Foundation, The Brain Foundation Netherlands, Dutch CardioVascular Alliance, Stryker, Medtronic, Penumbra and CONTRAST","award":["01-002-2022-0126 CONTRAST 2.0"],"award-info":[{"award-number":["01-002-2022-0126 CONTRAST 2.0"]}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:p>This study investigated vasoconstriction in the larger pial arteries, a network relatively underexplored in vascular stroke research, during and after ischemic stroke. By measuring vessel diameters along the entire vessel length, we uncovered effects of local constriction on vessel irregularity and resistance not reported before in vascular literature. By imaging during occlusion and hyperacutely after reperfusion, this study investigated thrombi formation and flow impairments at critical time points, providing insight lacking in prior research.<\/jats:p>","DOI":"10.1152\/ajpheart.00289.2026","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T21:21:13Z","timestamp":1780435273000},"page":"H153-H165","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Cerebral vascular diameter and flow irregularities due to ischemic stroke after middle cerebral artery occlusion"],"prefix":"10.1152","volume":"331","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8507-9172","authenticated-orcid":false,"given":"Moeed Raza","family":"Khokhar","sequence":"first","affiliation":[{"name":"University of Amsterdam","place":["The Netherlands"]},{"name":"Amsterdam Neuroscience","place":["The Netherlands"]},{"name":"Amsterdam Cardiovascular Sciences","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2845-1378","authenticated-orcid":false,"given":"Paul","family":"Bloemen","sequence":"additional","affiliation":[{"name":"University of Amsterdam","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ed","family":"van Bavel","sequence":"additional","affiliation":[{"name":"University of Amsterdam","place":["The Netherlands"]},{"name":"Amsterdam Neuroscience","place":["The Netherlands"]},{"name":"Amsterdam Cardiovascular Sciences","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6609-2206","authenticated-orcid":false,"given":"Inge A.","family":"Mulder","sequence":"additional","affiliation":[{"name":"University of Amsterdam","place":["The Netherlands"]},{"name":"Amsterdam Neuroscience","place":["The Netherlands"]},{"name":"Amsterdam Cardiovascular Sciences","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1177\/17474930211065917"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411587"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.19.9.1083"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2021.5070"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.5853\/jos.2019.02978"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-199402000-00004"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A7177"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awad401"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1038\/nature13165"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1097\/00004647-200404000-00003"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.350699"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092100211"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X16680636"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1117\/1.NPh.2.2.025006"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-020-02683-3"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.108260"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-02360-6"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00719"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S56071"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2010.66"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3791\/2761"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.21037\/qims-20-920"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-019-00710-1"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0040022"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1080\/02699052.2016.1195518"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2021.109179"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-8993(00)02543-9"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-69122-8"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-018-0637-8"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.021640"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-023-01367-3"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2025.2036"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.10800"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X231208476"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.122.040972"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1177\/23969873251317347"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-012-0230-5"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2021.109434"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2017.14538"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.552513"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.32.7.1552"}],"container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpheart.00289.2026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T18:38:15Z","timestamp":1781807895000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpheart.00289.2026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,1]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7,1]]}},"alternative-id":["10.1152\/ajpheart.00289.2026"],"URL":"https:\/\/doi.org\/10.1152\/ajpheart.00289.2026","relation":{},"ISSN":["0363-6135","1522-1539"],"issn-type":[{"value":"0363-6135","type":"print"},{"value":"1522-1539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,1]]},"assertion":[{"value":"2026-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-16","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}