{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:43:06Z","timestamp":1792460586597,"version":"4.5.0"},"reference-count":13,"publisher":"American Physiological Society","issue":"3","funder":[{"name":"University of Texas at Arlington College of Nursing and Health Innovation"},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["827597"],"award-info":[{"award-number":["827597"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["20PRE34990010"],"award-info":[{"award-number":["20PRE34990010"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"published-print":{"date-parts":[[2021,9,1]]},"abstract":"<jats:p> This study was the first to investigate the persistent effects of COVID-19 on vascular function in otherwise healthy young adults. We demonstrated that peripheral macrovascular and microvascular vasodilation was significantly blunted in young adults still symptomatic from COVID-19 beyond the acute phase (&gt;4\u2009wk from diagnosis), whereas those who become asymptomatic have similar vascular function compared with controls who never had COVID-19. In contrast, cerebral vascular function and central arterial stiffness were unaffected irrespective of COVID-19 symptomology. <\/jats:p>","DOI":"10.1152\/ajpheart.00368.2021","type":"journal-article","created":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T14:10:13Z","timestamp":1627049413000},"page":"H479-H484","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":53,"title":["Blunted peripheral but not cerebral vasodilator function in young otherwise healthy adults with persistent symptoms following COVID-19"],"prefix":"10.1152","volume":"321","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9635-1117","authenticated-orcid":true,"given":"Damsara","family":"Nandadeva","sequence":"first","affiliation":[{"name":"Department of Kinesiology, University of Texas at Arlington, Arlington, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0239-005X","authenticated-orcid":true,"given":"Benjamin E.","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, University of Texas at Arlington, Arlington, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1624-8778","authenticated-orcid":true,"given":"Brandi Y.","family":"Stephens","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, University of Texas at Arlington, Arlington, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann-Katrin","family":"Grotle","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, University of Texas at Arlington, Arlington, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel J.","family":"Skow","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, University of Texas at Arlington, Arlington, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela J.","family":"Middleton","sequence":"additional","affiliation":[{"name":"Health Services, University of Texas at Arlington, Arlington, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence P.","family":"Haseltine","sequence":"additional","affiliation":[{"name":"North Texas Genome Center, University of Texas at Arlington, Arlington, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Fadel","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, University of Texas at Arlington, Arlington, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30937-5"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01283-z"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00897.2020"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1113\/EP089481"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.0830"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.51350"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz350"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00082.2019"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1113\/EP086446"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00906.2006"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abf8396"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2004.08.036"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.102.9.994"}],"container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpheart.00368.2021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T12:16:02Z","timestamp":1628597762000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpheart.00368.2021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,1]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,9,1]]}},"alternative-id":["10.1152\/ajpheart.00368.2021"],"URL":"https:\/\/doi.org\/10.1152\/ajpheart.00368.2021","relation":{},"ISSN":["0363-6135","1522-1539"],"issn-type":[{"value":"0363-6135","type":"print"},{"value":"1522-1539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,1]]},"assertion":[{"value":"2021-07-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}