{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T06:40:01Z","timestamp":1794465601825,"version":"4.9.1"},"reference-count":45,"publisher":"American Physiological Society","issue":"5","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes for Health","doi-asserted-by":"crossref","award":["R01-DK124199"],"award-info":[{"award-number":["R01-DK124199"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes for Health","doi-asserted-by":"crossref","award":["R01HL122309"],"award-info":[{"award-number":["R01HL122309"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes for Health","doi-asserted-by":"crossref","award":["R21-AG086751"],"award-info":[{"award-number":["R21-AG086751"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:p> Hif2\u03b1 in neutrophils increases infarct size, cardiac dysfunction, and ventricular scar after myocardial infarction. Hif2\u03b1 in neutrophils supports neutrophil survival via cIAP-1 signaling and delays macrophage engulfment. <\/jats:p>","DOI":"10.1152\/ajpheart.00392.2024","type":"journal-article","created":{"date-parts":[[2024,9,27]],"date-time":"2024-09-27T14:45:09Z","timestamp":1727448309000},"page":"H1230-H1243","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Hypoxia-inducible factor-2\u03b1 enhances neutrophil survival to promote cardiac injury following myocardial infarction"],"prefix":"10.1152","volume":"327","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6283-0710","authenticated-orcid":false,"given":"Enzo B.","family":"Piccolo","sequence":"first","affiliation":[{"name":"Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7045-0846","authenticated-orcid":false,"given":"Zhi-Dong","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mallory E.","family":"Filipp","sequence":"additional","affiliation":[{"name":"Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7462-3898","authenticated-orcid":false,"given":"David P.","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1387-7058","authenticated-orcid":false,"given":"Edward B.","family":"Thorp","sequence":"additional","affiliation":[{"name":"Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5689-1100","authenticated-orcid":false,"given":"Ronen","family":"Sumagin","sequence":"additional","affiliation":[{"name":"Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.813493"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7218a3"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32284-2"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-018-0686-x"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1126\/science.1195491"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-019-0746-x"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw002"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2003.10.011"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-019-0326-7"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-022-00824-4"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3390\/cells10071676"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.303577"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2022.102191"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.120.317200"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2019.107424"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvw024"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2018.12.004"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20200667"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20040624"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-05-500207"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3322"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0608382104"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvae144"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.3791\/50586"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.108073"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M011774200"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-2518"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.216226"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-09503-8"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.04.111"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1807711115"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-012-2352-6"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-13-0798"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2020.04.002"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2022.01.012"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1186\/1755-1536-6-11"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/s0092-8674(03)00154-5"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1172\/JCI23865"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2018.05.004"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1172\/JCI39506"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020007505"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1038\/nm1468"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1038\/nm1248"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2024.02.005"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.10.037"}],"container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpheart.00392.2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T12:46:19Z","timestamp":1730119579000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpheart.00392.2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,1]]},"references-count":45,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,11,1]]}},"alternative-id":["10.1152\/ajpheart.00392.2024"],"URL":"https:\/\/doi.org\/10.1152\/ajpheart.00392.2024","relation":{},"ISSN":["0363-6135","1522-1539"],"issn-type":[{"value":"0363-6135","type":"print"},{"value":"1522-1539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,1]]},"assertion":[{"value":"2024-06-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-04","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}