{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T18:59:41Z","timestamp":1790103581689,"version":"4.0.1"},"reference-count":27,"publisher":"American Physiological Society","issue":"4","funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["RGPIN-2021-02563"],"award-info":[{"award-number":["RGPIN-2021-02563"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:p>\n                    This study evaluates ventricular-arterial coupling using traditional E\n                    <jats:sub>a<\/jats:sub>\n                    \/E\n                    <jats:sub>es<\/jats:sub>\n                    and a novel pulse wave velocity\/global longitudinal strain (PWV\/GLS) ratio during exercise and head-up tilt. E\n                    <jats:sub>a<\/jats:sub>\n                    \/E\n                    <jats:sub>es<\/jats:sub>\n                    decreased with graded exercise but was insensitive to postural stress. In contrast, PWV\/GLS detected tilt-related changes at rest but showed dampened responsiveness to exercise intensity. 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